Absolute determination of single-stranded and self-complementary adeno-associated viral vector genome titers by droplet digital PCR. (Q38831889)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24328707%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Absolute determination of single-stranded and self-complementary adeno-associated viral vector genome titers by droplet digital PCR (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24328707%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

4

1 reference

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3 March 2020

author name string

Martin Lock

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24328707%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Mauricio R Alvira

series ordinal

2

1 reference

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3 March 2020

Shu-Jen Chen

series ordinal

3

1 reference

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3 March 2020

publication date

14 February 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24328707%20AND%20SRC:MED&resulttype=core&format=json

Human gene therapy methods

3 March 2020

published in

1 reference

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3 March 2020

volume

25

1 reference

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3 March 2020

issue

2

1 reference

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3 March 2020

page(s)

115-125

1 reference

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describes a project that uses

3 March 2020

1 reference

Viral diagnostics in the era of digital polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Limitations of encapsidation of recombinant self-complementary adeno-associated viral genomes in different serotype capsids and their quantitation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Systemic errors in quantitative polymerase chain reaction titration of self-complementary adeno-associated viral vectors and improved alternative methods

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Evaluation of a droplet digital polymerase chain reaction format for DNA copy number quantification

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

High-throughput droplet digital PCR system for absolute quantitation of DNA copy number

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Native molecular state of adeno-associated viral vectors revealed by single-molecule sequencing

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Good manufacturing practice production of self-complementary serotype 8 adeno-associated viral vector for a hemophilia B clinical trial

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Safety and tolerability of putaminal AADC gene therapy for Parkinson disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Effect of gene therapy on visual function in Leber's congenital amaurosis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Safety and efficacy of gene transfer for Leber's congenital amaurosis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Results from a phase I safety trial of hAADC gene therapy for Parkinson disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Analysis of particle content of recombinant adeno-associated virus serotype 8 vectors by ion-exchange chromatography.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Molecular quantification of environmental DNA using microfluidics and digital PCR.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Evaluation of digital PCR for absolute DNA quantification

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Quantification of adeno-associated virus particles and empty capsids by optical density measurement

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3991984

Gene therapies advance, but some see manufacturing challenges

22 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24328707

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1089/HGTB.2013.131

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24328707%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24328707%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

24328707

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24328707%20AND%20SRC:MED&resulttype=core&format=json