Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity (Q38839149)

6 September 2017

Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity (English)

1 reference

6 September 2017

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4

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1 June 2020

Christian Touriol

11

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1 June 2020

author name string

Arnaud Jabouille

1

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1 June 2020

Maylis Delugin

2

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1 June 2020

Raphaël Pineau

3

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1 June 2020

Fabienne Soulet

5

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1 June 2020

Stéphanie Lhomond

6

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1 June 2020

Nestor Pallares-Lupon

7

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1 June 2020

Hervé Prats

8

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1 June 2020

Andreas Bikfalvi

9

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1 June 2020

Eric Chevet

10

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1 June 2020

Michel Moenner

12

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1 June 2020

language of work or name

English

0 references

publication date

23 July 2015

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6 September 2017

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1 June 2020

volume

6

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1 June 2020

issue

28

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1 June 2020

page(s)

24922-24934

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describes a project that uses

1 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4694804/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

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Getting RIDD of RNA: IRE1 in cell fate regulation

9 September 2017

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Endoplasmic reticulum stress-activated transcription factor ATF6α requires the disulfide isomerase PDIA5 to modulate chemoresistance

9 September 2017

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Multiple autophosphorylations significantly enhance the endoribonuclease activity of human inositol requiring enzyme 1α.

9 September 2017

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Induction of the unfolded protein response drives enhanced metabolism and chemoresistance in glioma cells

9 September 2017

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Targeting the unfolded protein response in disease.

9 September 2017

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Acquired resistance to anti-VEGF therapy in glioblastoma is associated with a mesenchymal transition

9 September 2017

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Posttranscriptional regulation of PER1 underlies the oncogenic function of IREα.

9 September 2017

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Mechanisms of evasive resistance to anti-VEGF therapy in glioblastoma

9 September 2017

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Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesis

9 September 2017

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Multiple roles of the ER stress sensor IRE1 demonstrated by gene targeting in rice

9 September 2017

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ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK.

9 September 2017

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Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors

9 September 2017

1 reference

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A systematic review of microRNA in glioblastoma multiforme: micro-modulators in the mesenchymal mode of migration and invasion

9 September 2017

1 reference

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IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

9 September 2017

1 reference

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The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

9 September 2017

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miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

9 September 2017

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The unfolded protein response: from stress pathway to homeostatic regulation

9 September 2017

1 reference

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PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolism

9 September 2017

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Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity

9 September 2017

1 reference

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Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response

9 September 2017

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Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma

9 September 2017

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microRNA-34a is tumor suppressive in brain tumors and glioma stem cells

9 September 2017

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The transcriptional network for mesenchymal transformation of brain tumours.

9 September 2017

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Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme

9 September 2017

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IRE1alpha controls cyclin A1 expression and promotes cell proliferation through XBP-1.

9 September 2017

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Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome

9 September 2017

1 reference

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Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

9 September 2017

1 reference

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The unfolded protein response signals through high-order assembly of Ire1

9 September 2017

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Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing

9 September 2017

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XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks

9 September 2017

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The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis

9 September 2017

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Patterns of somatic mutation in human cancer genomes

9 September 2017

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Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression

9 September 2017

1 reference

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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

9 September 2017

1 reference

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Discordance of UPR signaling by ATF6 and Ire1p-XBP1 with levels of target transcripts

9 September 2017

1 reference

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694804

The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694804

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694804

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694804

IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694804

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694804

The glial precursor proteoglycan, NG2, is expressed on tumour neovasculature by vascular pericytes in human malignant brain tumours.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694804

Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth.

14 September 2017

1 reference

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Autocrine control of glioma cells adhesion and migration through IRE1α-mediated cleavage of SPARC mRNA.

17 June 2018

1 reference

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Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness.

22 August 2018

1 reference

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Gene expression profiling of gliomas strongly predicts survival

22 August 2018

1 reference

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Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

22 August 2018

1 reference

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22 August 2018

Identifiers

DOI

10.18632/ONCOTARGET.4679

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26325176%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26325176%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

26325176

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26325176%20AND%20SRC:MED&resulttype=core&format=json