Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth. (Q41844309)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20028872%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth (English)

1 reference

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15 January 2020

9

1 reference

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15 January 2020

6

Geoffrey C Gurtner

1 reference

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15 January 2020

author name string

Michael T Spiotto

1

1 reference

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15 January 2020

Alice Banh

2

1 reference

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15 January 2020

Ioanna Papandreou

3

1 reference

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15 January 2020

Hongbin Cao

4

1 reference

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15 January 2020

Michael G Galvez

5

1 reference

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15 January 2020

Nicholas C Denko

7

1 reference

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15 January 2020

Quynh Thu Le

8

1 reference

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15 January 2020

language of work or name

English

0 references

publication date

22 December 2009

1 reference

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15 January 2020

1 reference

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15 January 2020

volume

70

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15 January 2020

issue

1

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15 January 2020

page(s)

78-88

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Targeting of mRNAs to their sites of unconventional splicing in the unfolded protein response.

15 January 2020

cites work

1 reference

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pXBP1(U), a negative regulator of the unfolded protein response activator pXBP1(S), targets ATF6 but not ATF4 in proteasome-mediated degradation.

6 June 2018

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Co-evolution of tumor cells and their microenvironment

6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer

6 June 2018

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"Translating" tumor hypoxia: unfolded protein response (UPR)-dependent and UPR-independent pathways

6 June 2018

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Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress

6 June 2018

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pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response

6 June 2018

1 reference

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The unfolded protein response: a novel component of the hypoxic stress response in tumors.

6 June 2018

1 reference

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ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

6 June 2018

1 reference

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XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

6 June 2018

1 reference

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Molecular characterization of the tumor microenvironment in breast cancer

6 June 2018

1 reference

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Hypoxia and glucose metabolism in malignant tumors: evaluation by [18F]fluoromisonidazole and [18F]fluorodeoxyglucose positron emission tomography imaging

6 June 2018

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Upregulation and overexpression of human X-box binding protein 1 (hXBP-1) gene in primary breast cancers

6 June 2018

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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

6 June 2018

1 reference

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Investigating hypoxic tumor physiology through gene expression patterns

6 June 2018

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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

6 June 2018

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Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development

6 June 2018

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

6 June 2018

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

6 June 2018

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6 June 2018

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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18 August 2018

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18 August 2018

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Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer

18 August 2018

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B- and T-cell development both involve activity of the unfolded protein response pathway.

18 August 2018

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Prediction of prognosis using standardized uptake value of 2-[(18)F] fluoro-2-deoxy-d-glucose positron emission tomography for nasopharyngeal carcinomas

18 August 2018

1 reference

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Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development.

18 August 2018

1 reference

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Involvement of endoplasmic reticulum stress after middle cerebral artery occlusion in mice.

18 August 2018

1 reference

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Analysis of the XBP1 splicing mechanism using endoplasmic reticulum stress-indicators.

18 August 2018

1 reference

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FDG-PET prediction of head and neck squamous cell cancer outcomes

18 August 2018

1 reference

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A transgenic mouse model for monitoring endoplasmic reticulum stress

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943832

Coevolution in the tumor microenvironment

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20028872

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The standardized uptake value for F-18 fluorodeoxyglucose is a sensitive predictive biomarker for cervical cancer treatment response and survival

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20028872

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-09-2747

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20028872%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20028872%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference