A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity (Q38843089)

6 September 2017

A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity (English)

1 reference

6 September 2017

5

Bert Vogelstein

0 references

Ivana Bozic

object named as

Ivana Bozic

series ordinal

2

0 references

Bartłomiej Waclaw

object named as

Bartlomiej Waclaw

series ordinal

1

0 references

Ralph H. Hruban

series ordinal

4

object named as

Ralph H Hruban

1 reference

6 September 2017

6

Martin A Nowak

1 reference

6 September 2017

3

Meredith E Pittman

1 reference

6 September 2017

language of work or name

English

0 references

publication date

26 August 2015

1 reference

6 September 2017

1 reference

6 September 2017

525

1 reference

6 September 2017

7568

1 reference

6 September 2017

261-264

1 reference

describes a project that uses

6 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4782800/fullTextXML

inferred from PubMed Central ID database lookup

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Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

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Evolution and phenotypic selection of cancer stem cells

9 September 2017

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Physical influences of the extracellular environment on cell migration

9 September 2017

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Timing and heterogeneity of mutations associated with drug resistance in metastatic cancers

9 September 2017

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PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

9 September 2017

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Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis

9 September 2017

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Spatial interactions and cooperation can change the speed of evolution of complex phenotypes

9 September 2017

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Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change.

9 September 2017

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Mechanical properties of growing melanocytic nevi and the progression to melanoma

9 September 2017

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Evolution of acquired resistance to anti-cancer therapy

9 September 2017

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Tumor genetic analyses of patients with metastatic renal cell carcinoma and extended benefit from mTOR inhibitor therapy

9 September 2017

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The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration

9 September 2017

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A multiphase model for three-dimensional tumor growth.

9 September 2017

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Physical biology in cancer. 5. The rocky road of metastasis: the role of cytoskeletal mechanics in cell migratory response to 3D matrix topography

9 September 2017

1 reference

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Combining two strategies to improve perfusion and drug delivery in solid tumors

9 September 2017

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Gene of the month: E-cadherin (CDH1).

9 September 2017

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Spatial stochastic models of cancer: fitness, migration, invasion

9 September 2017

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Tumor growth dynamics: insights into evolutionary processes

9 September 2017

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Evolutionary dynamics of cancer in response to targeted combination therapy

9 September 2017

1 reference

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A single institution's 26-year experience with nonfunctional pancreatic neuroendocrine tumors: a validation of current staging systems and a new prognostic nomogram.

9 September 2017

1 reference

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Modeling Tumor-Associated Edema in Gliomas during Anti-Angiogenic Therapy and Its Impact on Imageable Tumor

9 September 2017

1 reference

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9 September 2017

Cancer genome landscapes

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Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.

9 September 2017

1 reference

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Fine tuning of tissues' viscosity and surface tension through contractility suggests a new role for α-catenin

9 September 2017

1 reference

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New insight into Ki67 expression at the invasive front in breast cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Soft matter models of developing tissues and tumors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

The impact of phenotypic switching on glioblastoma growth and invasion

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Diversity of dynamics and morphologies of invasive solid tumors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Selective sweeps in growing microbial colonies

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

9 September 2017

1 reference

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Model for in vivo progression of tumors based on co-evolving cell population and vasculature

9 September 2017

1 reference

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A quantitative test of population genetics using spatiogenetic patterns in bacterial colonies.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

RGB marking facilitates multicolor clonal cell tracking

9 September 2017

1 reference

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iDynoMiCS: next-generation individual-based modelling of biofilms

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Tumour evolution inferred by single-cell sequencing

9 September 2017

1 reference

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Toward an Ising model of cancer and beyond

9 September 2017

1 reference

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Fluidization of tissues by cell division and apoptosis

9 September 2017

1 reference

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Distant metastasis occurs late during the genetic evolution of pancreatic cancer

9 September 2017

1 reference

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Accumulation of driver and passenger mutations during tumor progression

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

AACR centennial series: the biology of cancer metastasis: historical perspective

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Selection in spatial stochastic models of cancer: migration as a key modulator of fitness

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Migration rules: tumours are conglomerates of self-metastases.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Multi-scale modelling of cancer cell intravasation: the role of cadherins in metastasis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Comparative lesion sequencing provides insights into tumor evolution

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Genetic progression and the waiting time to cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

A multiscale model for avascular tumor growth

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Drug resistance in cancer: principles of emergence and prevention

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Metapopulation dynamics and spatial heterogeneity in cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Prevalence of somatic alterations in the colorectal cancer cell genome

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Elasticity of normal and cancerous human bladder cells studied by scanning force microscopy.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Modeling the effect of deregulated proliferation and apoptosis on the growth dynamics of epithelial cell populations in vitro

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Spatial Moran models, II: cancer initiation in spatially structured tissue

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Multifocality and recurrence risk: a quantitative model of field cancerization

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Spatial invasion dynamics on random and unstructured meshes: implications for heterogeneous tumor populations

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

The effect of one additional driver mutation on tumor progression.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Spatial structure increases the waiting time for cancer.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Dynamics of targeted cancer therapy

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Quantifying the role of angiogenesis in malignant progression of gliomas: in silico modeling integrates imaging and histology

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Simulated brain tumor growth dynamics using a three-dimensional cellular automaton.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

A stochastic model for the origin and treatment of tumors containing drug-resistant cells.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Spatial evolution of tumors with successive driver mutations.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Survival probabilities at spherical frontiers.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Long-term dynamics of adaptation in asexual populations

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

A hybrid model of tumor-stromal interactions in breast cancer.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Clinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Reproduction-time statistics and segregation patterns in growing populations.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Evolution of resistance and progression to disease during clonal expansion of cancer.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Comparing the growth kinetics of cell populations in two and three dimensions.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Spatial stochastic models for cancer initiation and progression

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Mathematical modelling of dynamic adaptive tumour-induced angiogenesis: clinical implications and therapeutic targeting strategies.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

A single-cell-based model of tumor growth in vitro: monolayers and spheroids

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Multicellular tumor spheroid in an off-lattice Voronoi-Delaunay cell model.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

An ordinary differential equation model for the multistep transformation to cancer.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

An evolutionary model of carcinogenesis

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Buckling instabilities of one-layered growing tissues.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

BacSim, a simulator for individual-based modelling of bacterial colony growth.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

The genetic origin of drug resistance in neoplasms: implications for systemic therapy.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782800

Mutational Pathway Determines Whether Drug Gradients Accelerate Evolution of Drug-Resistant Cells

22 August 2018

1 reference

12 December 2020

Emergence of a subpopulation in a computational model of tumor growth

1 reference

12 December 2020

Measuring the elastic modulus of ex vivo small tissue samples

1 reference

12 December 2020

Establishment of epidermal cell columns in mammalian skin: Computer simulation

1 reference

12 December 2020

A hybrid mathematical model of solid tumour invasion: the importance of cell adhesion

1 reference

12 December 2020

Undulation instability of epithelial tissues

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE14971

1 reference

journals/nature/WaclawBPHVN15

6 September 2017

1 reference

1 reference

DBLP Dataset 2021-01-02

release_nqsmzagktzh5vdudqm565o5cwy

28 January 2021

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nqsmzagktzh5vdudqm565o5cwy

24 November 2022

mapped directly with Wikidata item

0 references

1 reference

6 September 2017

PubMed publication ID

26308893

1 reference