Pin1, the Master Orchestrator of Bone Cell Differentiation (Q38844443)

6 September 2017

1 reference

title

Pin1, the Master Orchestrator of Bone Cell Differentiation (English)

1 reference

6 September 2017

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27225727%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Won-Joon Yoon

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27225727%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Hyun-Mo Ryoo

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27225727%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

publication date

25 May 2016

1 reference

Journal of Cellular Physiology

6 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27225727%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

232

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27225727%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27225727%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

2339-2347

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27225727%20AND%20SRC:MED&resulttype=core&format=json

Prolyl isomerase pin1 protects mice from endotoxin shock

7 June 2020

cites work

1 reference

Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT.

21 January 2018

1 reference

A Smad action turnover switch operated by WW domain readers of a phosphoserine code

21 January 2018

1 reference

Mechanisms for the bone anabolic effect of parathyroid hormone treatment in humans

21 January 2018

1 reference

The prolyl isomerase Pin1 modulates development of CD8+ cDC in mice

21 January 2018

1 reference

Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction

21 January 2018

1 reference

Wnt3a stimulates Mepe, matrix extracellular phosphoglycoprotein, expression directly by the activation of the canonical Wnt signaling pathway and indirectly through the stimulation of autocrine Bmp-2 expression.

21 January 2018

1 reference

PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter.

21 January 2018

1 reference

Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells

21 January 2018

1 reference

Effects of FGF-2/-9 in calvarial bone cell cultures: differentiation stage-dependent mitogenic effect, inverse regulation of BMP-2 and noggin, and enhancement of osteogenic potential

21 January 2018

1 reference

Role of fibroblast growth factor 2 and Wnt signaling in anabolic effects of parathyroid hormone on bone formation

21 January 2018

1 reference

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

21 January 2018

1 reference

Vitamin E decreases bone mass by stimulating osteoclast fusion.

21 January 2018

1 reference

Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling

21 January 2018

1 reference

Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development

21 January 2018

1 reference

Identification and functional characterization of ERK/MAPK phosphorylation sites in the Runx2 transcription factor.

21 January 2018

1 reference

Treatment needs and current options for postmenopausal osteoporosis.

21 January 2018

1 reference

Mitogen-activated protein kinase pathways in osteoblasts

21 January 2018

1 reference

How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow

21 January 2018

1 reference

Nuclear exclusion of Smad2 is a mechanism leading to loss of competence

21 January 2018

1 reference

Multisite protein phosphorylation makes a good threshold but can be a poor switch

21 January 2018

1 reference

Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors

21 January 2018

1 reference

Opposing TNF-α/IL-1β- and BMP-2-activated MAPK signaling pathways converge on Runx2 to regulate BMP-2-induced osteoblastic differentiation

21 January 2018

1 reference

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

21 January 2018

1 reference

Pin1 regulates osteoclast fusion through suppression of the master regulator of cell fusion DC-STAMP.

21 January 2018

1 reference

Pin1-mediated prolyl isomerization of Runx1 affects PU.1 expression in pre-monocytes.

21 January 2018

1 reference

Bone morphogenetic protein-2 stimulates Runx2 acetylation

21 January 2018

1 reference

The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2

21 January 2018

1 reference

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

21 January 2018

1 reference

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

21 January 2018

1 reference

Fibroblast growth factor expression in the postnatal growth plate

21 January 2018

1 reference

PI3-kinase/p38 kinase-dependent E2F1 activation is critical for Pin1 induction in tamoxifen-resistant breast cancer cells

21 January 2018

1 reference

Prolyl isomerase Pin1 enhances osteoblast differentiation through Runx2 regulation

21 January 2018

1 reference

Prolyl isomerase Pin1 regulates the osteogenic activity of Osterix

21 January 2018

1 reference

Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function

21 January 2018

1 reference

Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease

21 January 2018

1 reference

Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance

21 January 2018

1 reference

Pin1 acts as a negative regulator of the G2/M transition by interacting with the Aurora-A-Bora complex.

21 January 2018

1 reference

Differentiation-dependent association of phosphorylated extracellular signal-regulated kinase with the chromatin of osteoblast-related genes

21 January 2018

1 reference

Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins

21 January 2018

1 reference

Pin1: Intimate involvement with the regulatory protein kinase networks in the global phosphorylation landscape

21 January 2018

1 reference

Prolyl cis-trans isomerization as a molecular timer

21 January 2018

1 reference

A human peptidyl-prolyl isomerase essential for regulation of mitosis

21 January 2018

1 reference

The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease

21 January 2018

1 reference

Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function

21 January 2018

1 reference

Prolyl isomerase Pin1 in cancer

21 January 2018

1 reference

The Rab2A GTPase promotes breast cancer stem cells and tumorigenesis via Erk signaling activation

21 January 2018

1 reference

Structural determinants of Smad function in TGF-β signaling.

21 January 2018

1 reference

Cadherins and Wnt signalling: a functional link controlling bone formation

21 January 2018

1 reference

TGFβ signalling in context

21 January 2018

1 reference

Pin1 promotes transforming growth factor-beta-induced migration and invasion

21 January 2018

1 reference

Cyclin-dependent kinases regulate the antiproliferative function of Smads

21 January 2018

1 reference

Linear Motif Atlas for Phosphorylation-Dependent Signaling

21 January 2018

1 reference

Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.

21 January 2018

1 reference

Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation

21 January 2018

1 reference

Pin1 inhibitors: Pitfalls, progress and cellular pharmacology

21 January 2018

1 reference

Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin

21 January 2018

1 reference

Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins

21 January 2018

1 reference

The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism.

21 January 2018

1 reference

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

21 January 2018

1 reference

PIN1 overexpression and beta-catenin gene mutations are distinct oncogenic events in human hepatocellular carcinoma

21 January 2018

1 reference

A critical step for JNK activation: isomerization by the prolyl isomerase Pin1

21 January 2018

1 reference

FGF2-activated ERK mitogen-activated protein kinase enhances Runx2 acetylation and stabilization

21 January 2018

1 reference

Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

21 January 2018

1 reference

Pin1 promotes GR transactivation by enhancing recruitment to target genes

21 January 2018

1 reference

Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent

21 January 2018

1 reference

Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

21 January 2018

1 reference

Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

21 January 2018

1 reference

Critical molecular switches involved in BMP-2-induced osteogenic differentiation of mesenchymal cells

21 January 2018

1 reference

The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins

21 January 2018

1 reference

Pin1 protein regulates Smad protein signaling and pulmonary fibrosis

21 January 2018

1 reference

Pin1 null mice exhibit low bone mass and attenuation of BMP signaling

21 January 2018

1 reference

Serine/threonine phosphatases: mechanism through structure

21 January 2018

1 reference

Pin1-mediated Modification Prolongs the Nuclear Retention of β-Catenin in Wnt3a-induced Osteoblast Differentiation.

21 January 2018

1 reference

Pin1 facilitates NF-κB activation and promotes tumour progression in human hepatocellular carcinoma

21 January 2018

1 reference

Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation

21 January 2018

1 reference

Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models

21 January 2018

1 reference

Dipentamethylene thiuram monosulfide is a novel inhibitor of Pin1.

21 January 2018

1 reference

Focus on the p38 MAPK signaling pathway in bone development and maintenance

21 January 2018

1 reference

Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation

21 January 2018

1 reference

Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

21 January 2018

1 reference

Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation

21 January 2018

1 reference

Opposing effects of Wnt and MAPK on BMP/Smad signal duration

21 January 2018

1 reference

Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

21 January 2018

1 reference

Wnt signaling in osteoblasts and bone diseases

21 January 2018

1 reference

Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis.

21 January 2018

1 reference

Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling.

21 January 2018

1 reference

Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2.

21 January 2018

1 reference

Pin1 as an anticancer drug target

21 January 2018

1 reference

Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

21 January 2018

1 reference

Role of DC-STAMP in cellular fusion of osteoclasts and macrophage giant cells

21 January 2018

1 reference

Axin2 controls bone remodeling through the beta-catenin-BMP signaling pathway in adult mice.

21 January 2018

1 reference

The loss of PIN1 deregulates cyclin E and sensitizes mouse embryo fibroblasts to genomic instability

21 January 2018

1 reference

PIN1, the cell cycle and cancer.

21 January 2018

1 reference

Prolyl isomerase Pin1-mediated conformational change and subnuclear focal accumulation of Runx2 are crucial for fibroblast growth factor 2 (FGF2)-induced osteoblast differentiation

21 January 2018

1 reference

Pin1 plays a critical role as a molecular switch in canonical BMP signaling.

21 January 2018

1 reference

Pin1-mediated Runx2 modification is critical for skeletal development

21 January 2018

1 reference

Alterations in intranuclear localization of Runx2 affect biological activity

21 January 2018

1 reference

Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

21 January 2018

1 reference

Bone and haematopoietic defects in mice lacking c-fos

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCP.25442

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27225727%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference