Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease (Q37891181)

24 August 2017

1 reference

title

Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease (English)

1 reference

24 August 2017

0 references

Tae Ho Lee

1

1 reference

PubMed ID

21682951

24 August 2017

Lucia Pastorino

series ordinal

2

1 reference

PubMed ID

21682951

24 August 2017

Kun Ping Lu

series ordinal

3

1 reference

24 August 2017

20 June 2011

1 reference

Expert Reviews in Molecular Medicine

24 August 2017

1 reference

24 August 2017

13

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24 August 2017

e21

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Alzheimer disease and cancer

24 August 2017

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The functional promoter polymorphism (-842G>C) in the PIN1 gene is associated with decreased risk of breast cancer in non-Hispanic white women 55 years and younger

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

p25/cyclin-dependent kinase 5 induces production and intraneuronal accumulation of amyloid beta in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

A novel functional variant (-842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

APP processing is regulated by cytoplasmic phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Regulation of amyloid beta-protein precursor by phosphorylation and protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Amyloid precursor protein trafficking, processing, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 regulates centrosome duplication, and its overexpression induces centrosome amplification, chromosome instability, and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

A common biological mechanism in cancer and Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Phosphorylation-specific prolyl isomerization: is there an underlying theme?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 interacts with c-Myb in a phosphorylation-dependent manner and regulates its transactivation activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

FAK phosphorylation by ERK primes ras-induced tyrosine dephosphorylation of FAK mediated by PIN1 and PTP-PEST

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Control of telomere length by the human telomeric protein TRF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Tau is essential to beta -amyloid-induced neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Mouse mutants reveal that putative protein interaction sites in the p53 proline-rich domain are dispensable for tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Shelterin: the protein complex that shapes and safeguards human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Essential role of mouse telomerase in highly proliferative organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 protein associates with neuronal lipofuscin: potential consequences in age-related neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Association study of the PIN1 gene with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Replicative senescence: the human fibroblast comes of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Regulation of telomerase by telomeric proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Switching and signaling at the telomere

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pinning down cell signaling, cancer and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

A role for Pin1 in mammalian germ cell development and spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Tau pathology in a family with dementia and a P301L mutation in tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

A human peptidyl-prolyl isomerase essential for regulation of mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The peptidylprolyl cis/trans-isomerase Pin1 modulates stress-induced dephosphorylation of Tau in neurons. Implication in a pathological mechanism related to Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 colocalization with phosphorylated tau in Alzheimer's disease and other tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Proline-directed pseudo-phosphorylation at AT8 and PHF1 epitopes induces a compaction of the paperclip folding of Tau and generates a pathological (MC-1) conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Evidence for a novel late-onset Alzheimer disease locus on chromosome 19p13.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Cdk5 deregulation in the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Mechanisms of tau-induced neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Prolyl cis-trans isomerization as a molecular timer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Oxidative stress signalling in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Association studies between common variants in prolyl isomerase Pin1 and the risk for late-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The role of mitogen-activated protein kinase pathways in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

DNA sequence variations in the prolyl isomerase Pin1 gene and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Centrosome aberrations: cause or consequence of cancer progression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Protein phosphorylation in signaling--50 years and counting

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Oncogenic kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

PIN1 promoter polymorphisms are associated with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Utilizing the peptidyl-prolyl cis-trans isomerase pin1 as a probe of its phosphorylated target proteins. Examples of binding to nuclear proteins in a human kidney cell line and to tau in Alzheimer's diseased brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Coactivator and corepressor complexes in nuclear receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pinning down HER2-ER crosstalk in SMRT regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

A protein kinase associated with paired helical filaments in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Duplicating dangerously: linking centrosome duplication and aneuploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Cdk5 is a key factor in tau aggregation and tangle formation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Insights into the catalytic mechanism of peptidyl prolyl cis/trans isomerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 affects Tau phosphorylation in response to Abeta oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Spermatogonial depletion in adult Pin1-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 promotes production of Alzheimer's amyloid beta from beta-cleaved amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 regulates the timing of mammalian primordial germ cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

21 January 2018

The genetics of ageing

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Phosphorylation-induced structural changes in the amyloid precursor protein cytoplasmic tail detected by NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Proteasomal degradation of human peptidyl prolyl isomerase pin1-pointing phospho Bcl2 toward dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

An immunohistochemical scoring system of prolyl isomerase Pin1 for predicting relapse of prostate carcinoma after radical prostatectomy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Prevalent overexpression of prolyl isomerase Pin1 in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 links the activities of c-Abl and p300 in regulating p73 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

On the shoulders of giants: p63, p73 and the rise of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

p73: Friend or foe in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The p53 pathway: positive and negative feedback loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

To die or not to die: how does p53 decide?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Oxidative stress and vascular smooth muscle cell growth: a mechanistic linkage by cyclophilin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The prolyl isomerase Pin1 in breast development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Membrane permeable cyclic peptidyl inhibitors against human Peptidylprolyl Isomerase Pin1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Structural Basis for High-Affinity Peptide Inhibition of Human Pin1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The p66shc adaptor protein controls oxidative stress response and life span in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

An essential role for Pin1 in Xenopus laevis embryonic development revealed by specific inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 as an anticancer drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

FOXO transcription factors in ageing and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

A phosphorylated prodrug for the inhibition of Pin1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The peptidyl-isomerase Pin1 regulates p27kip1 expression through inhibition of Forkhead box O tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Structure-based design of novel human Pin1 inhibitors (I)

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Protein oxidation and proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Structure-guided design of alpha-amino acid-derived Pin1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Nanomolar inhibitors of the peptidyl prolyl cis/trans isomerase Pin1 from combinatorial peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Redox homeostasis and cellular stress response in aging and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Stable suppression of tumorigenicity by Pin1-targeted RNA interference in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Telomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 expression contributes to lung cancer: Prognosis and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

TRF2 Protects Human Telomeres from End-to-End Fusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Centrosomes in cellular regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Centrosome composition and microtubule anchoring mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The rotamase Pin1 is up-regulated, hypophosphorylated and required for cell cycle progression in head and neck squamous cell carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Cdk2 and Pin1 negatively regulate the transcriptional corepressor SMRT

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Peptidyl-prolyl isomerase Pin1 markedly enhances the oncogenic activity of the rel proteins in the nuclear factor-kappaB family

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The peptidyl-prolyl isomerase Pin1 regulates phospho-Ser77 retinoic acid receptor alpha stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARalpha and PML-RARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Regulation of Raf-1 by direct feedback phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

Pin1 promoter polymorphisms in hepatocellular carcinoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

High Pin1 expression is associated with tumor progression in colorectal cancer

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

Apoptosis and cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

Ablation of a peptidyl prolyl isomerase Pin1 from p53-null mice accelerated thymic hyperplasia by increasing the level of the intracellular form of Notch1

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

Pin1 is required for the Ser727 phosphorylation-dependent Stat3 activity

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

Inverse association of Pin1 and tau accumulation in Alzheimer's disease hippocampus

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

Earliest stages of tau conformational changes are related to the appearance of a sequence of specific phospho-dependent tau epitopes in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

Transient structure of the amyloid precursor protein cytoplasmic tail indicates preordering of structure for binding to cytosolic factors

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

Pin1: a new genetic link between Alzheimer's disease, cancer and aging.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411001906

7 January 2021

10.1017/S1462399411001906

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21682951