Metformin inhibits the proliferation, metastasis, and cancer stem-like sphere formation in osteosarcoma MG63 cells in vitro (Q38854319)

7 September 2017

title

Metformin inhibits the proliferation, metastasis, and cancer stem-like sphere formation in osteosarcoma MG63 cells in vitro (English)

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7 September 2017

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Xu Chen

1

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7 September 2017

Chuanzhen Hu

2

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7 September 2017

Weibin Zhang

3

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7 September 2017

Yuhui Shen

4

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7 September 2017

Jun Wang

5

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7 September 2017

Fangqiong Hu

6

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7 September 2017

Pei Yu

7

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7 September 2017

publication date

13 July 2015

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7 September 2017

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7 September 2017

volume

36

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7 September 2017

issue

12

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7 September 2017

page(s)

9873-9883

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CXCL5/CXCR2 axis promotes bladder cancer cell migration and invasion by activating PI3K/AKT-induced upregulation of MMP2/MMP9.

7 September 2017

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Cadmium exposure inhibits MMP2 and MMP9 activities in the prostate and testis.

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Icaritin suppresses the proliferation of human osteosarcoma cells in vitro by increasing apoptosis and decreasing MMP expression

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Metformin targets ovarian cancer stem cells in vitro and in vivo

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AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

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Metformin synergistically enhances antitumor activity of histone deacetylase inhibitor trichostatin a against osteosarcoma cell line

21 January 2018

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Metformin sensitizes human bladder cancer cells to TRAIL-induced apoptosis through mTOR/S6K1-mediated downregulation of c-FLIP.

21 January 2018

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AMPK/mTOR-mediated inhibition of survivin partly contributes to metformin-induced apoptosis in human gastric cancer cell

21 January 2018

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Metformin displays anti-myeloma activity and synergistic effect with dexamethasone in in vitro and in vivo xenograft models.

21 January 2018

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Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expression

21 January 2018

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Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

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CXCR4 regulates the early extravasation of metastatic tumor cells in vivo

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MiR-210 expression reverses radioresistance of stem-like cells of oesophageal squamous cell carcinoma

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Bufalin inhibits the differentiation and proliferation of human osteosarcoma cell line hMG63-derived cancer stem cells

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Berberis libanotica Ehrenb extract shows anti-neoplastic effects on prostate cancer stem/progenitor cells.

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21 January 2018

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The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

21 January 2018

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TOR signaling in growth and metabolism

21 January 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

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PTEN deficiency is associated with reduced sensitivity to mTOR inhibitor in human bladder cancer through the unhampered feedback loop driving PI3K/Akt activation

21 January 2018

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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

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Clinicopathological significance of MMP-2 and its specific inhibitor TIMP-2 in gastric cancer

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12 December 2020

Pattern of relapse in patients with osteosarcoma of the extremities treated with neoadjuvant chemotherapy

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12 December 2020

Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.

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12 December 2020

Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines

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12 December 2020

Effects of metformin on retinoblastoma growth in vitro and in vivo.

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12 December 2020

A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer

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12 December 2020

Metformin decreases lung cancer risk in diabetic patients in a dose-dependent manner

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12 December 2020

Metformin inhibits cell growth by upregulating microRNA-26a in renal cancer cells.

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12 December 2020

Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer

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12 December 2020

Metformin may function as anti-cancer agent via targeting cancer stem cells: the potential biological significance of tumor-associated miRNAs in breast and pancreatic cancers

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12 December 2020

Cisplatin combined with metformin inhibits migration and invasion of human nasopharyngeal carcinoma cells by regulating E-cadherin and MMP-9.

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12 December 2020

Effect of metformin on apoptosis, cell cycle arrest migration and invasion of A498 cells

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12 December 2020

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12 December 2020

Metformin inhibits ovarian cancer growth and increases sensitivity to paclitaxel in mouse models.

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12 December 2020

Dual effect of metformin on growth inhibition and oestradiol production in breast cancer cells.

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12 December 2020

Low concentrations of metformin selectively inhibit CD133⁺ cell proliferation in pancreatic cancer and have anticancer action

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12 December 2020

Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells

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12 December 2020

Glioblastoma stem cells: a new target for metformin and arsenic trioxide.

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12 December 2020

Metformin inhibits growth and sensitizes osteosarcoma cell lines to cisplatin through cell cycle modulation

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12 December 2020

Metformin: actions and indications for use in non-insulin-dependent diabetes mellitus

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12 December 2020

Patterns of MMP-2 and MMP-9 expression in human cancer cell lines

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12 December 2020

Baicalein inhibits the invasion and metastatic capabilities of hepatocellular carcinoma cells via down-regulation of the ERK pathway

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12 December 2020

Common musculoskeletal tumors of childhood and adolescence

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12 December 2020

Metformin inhibits tumor cell migration via down-regulation of MMP9 in tamoxifen-resistant breast cancer cells

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12 December 2020

Osteosarcoma relapse after combined modality therapy: an analysis of unselected patients in the Cooperative Osteosarcoma Study Group (COSS)

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12 December 2020

Knockdown of IRX2 inhibits osteosarcoma cell proliferation and invasion by the AKT/MMP9 signaling pathway

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12 December 2020

10.1007/S13277-015-3751-1

Identifiers

DOI

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Dimensions Publication ID

7 September 2017

1022680919

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