Nanodiscs for structural and functional studies of membrane proteins (Q38858495)

7 September 2017

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title

Nanodiscs for structural and functional studies of membrane proteins (English)

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7 September 2017

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1

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7 September 2017

Stephen G Sligar

2

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7 September 2017

publication date

7 June 2016

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Nature Structural & Molecular Biology

7 September 2017

published in

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7 September 2017

volume

23

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7 September 2017

issue

6

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7 September 2017

page(s)

481-486

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Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold Proteins

7 September 2017

cites work

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Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size

21 January 2018

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Membrane protein assembly into Nanodiscs

21 January 2018

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Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers

21 January 2018

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The styrene-maleic acid copolymer: a versatile tool in membrane research

21 January 2018

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The use of amphipols for solution NMR studies of membrane proteins: advantages and constraints as compared to other solubilizing media

21 January 2018

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Magic-angle spinning solid-state NMR spectroscopy of nanodisc-embedded human CYP3A4.

21 January 2018

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Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions

21 January 2018

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The Local Phospholipid Environment Modulates the Activation of Blood Clotting

21 January 2018

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Conformational analysis of human ATP-binding cassette transporter ABCB1 in lipid nanodiscs and inhibition by the antibodies MRK16 and UIC2.

21 January 2018

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Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

21 January 2018

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Advances in the use of nanoscale bilayers to study membrane protein structure and function.

21 January 2018

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Characterization of the insertase BamA in three different membrane mimetics by solution NMR spectroscopy

21 January 2018

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Smaller Nanodiscs are Suitable for Studying Protein Lipid Interactions by Solution NMR.

21 January 2018

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Influences of membrane mimetic environments on membrane protein structures.

21 January 2018

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Following Natures Lead: On the Construction of Membrane-Inserted Toxins in Lipid Bilayer Nanodiscs.

21 January 2018

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Architecture and conformational switch mechanism of the ryanodine receptor

21 January 2018

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Identification of GPCR-interacting cytosolic proteins using HDL particles and mass spectrometry-based proteomic approach

21 January 2018

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Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

21 January 2018

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Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs

21 January 2018

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Cryo-EM structure of the ribosome–SecYE complex in the membrane environment

21 January 2018

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Three dimensional structure of the anthrax toxin translocon-lethal factor complex by cryo-electron microscopy

21 January 2018

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Three-dimensional structure of the anthrax toxin pore inserted into lipid nanodiscs and lipid vesicles

21 January 2018

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Recreation of the terminal events in physiological integrin activation

21 January 2018

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Factor VIII organisation on nanodiscs with different lipid composition.

21 January 2018

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An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes

21 January 2018

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Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.

21 January 2018

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Structural analysis of nanoscale self-assembled discoidal lipid bilayers by solid-state NMR spectroscopy.

21 January 2018

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Solid-state NMR of the Yersinia pestis outer membrane protein Ail in lipid bilayer nanodiscs sedimented by ultracentrifugation

21 January 2018

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Optimizing nanodiscs and bicelles for solution NMR studies of two β-barrel membrane proteins

21 January 2018

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NMR Dynamics of Transmembrane and Intracellular Domains of p75NTR in Lipid-Protein Nanodiscs.

21 January 2018

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Full engagement of liganded maltose-binding protein stabilizes a semi-open ATP-binding cassette dimer in the maltose transporter

21 January 2018

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Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

21 January 2018

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Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site

21 January 2018

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Modulation of the cytochrome P450 reductase redox potential by the phospholipid bilayer

21 January 2018

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Thermotropic phase transition in soluble nanoscale lipid bilayers.

21 January 2018

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Cell-free protein synthesis of membrane (1,3)-β-d-glucan (curdlan) synthase: co-translational insertion in liposomes and reconstitution in nanodiscs

21 January 2018

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Small-angle scattering determination of the shape and localization of human cytochrome P450 embedded in a phospholipid nanodisc environment

21 January 2018

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Stealth carriers for low-resolution structure determination of membrane proteins in solution

21 January 2018

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Monitoring shifts in the conformation equilibrium of the membrane protein cytochrome P450 reductase (POR) in nanodiscs

21 January 2018

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Single molecule activity measurements of cytochrome P450 oxidoreductase reveal the existence of two discrete functional states

21 January 2018

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Allosteric effects on substrate dissociation from cytochrome P450 3A4 in nanodiscs observed by ensemble and single-molecule fluorescence spectroscopy

21 January 2018

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Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β2AR.

21 January 2018

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Single-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks

21 January 2018

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Characterizing the membrane-bound state of cytochrome P450 3A4: structure, depth of insertion, and orientation

21 January 2018

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Rhodopsin in nanodiscs has native membrane-like photointermediates

21 January 2018

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Green proteorhodopsin reconstituted into nanoscale phospholipid bilayers (nanodiscs) as photoactive monomers

21 January 2018

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Unveiling the crucial intermediates in androgen production

21 January 2018

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Active site proton delivery and the lyase activity of human CYP17A1.

21 January 2018

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Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins

21 January 2018

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Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding

21 January 2018

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Mechanism of drug-drug interactions mediated by human cytochrome P450 CYP3A4 monomer

21 January 2018

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Phage display selections for affinity reagents to membrane proteins in nanodiscs

21 January 2018

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Reconstitution of respiratory oxidases in membrane nanodiscs for investigation of proton-coupled electron transfer

21 January 2018

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Photoelectrochemical complexes for solar energy conversion that chemically and autonomously regenerate

21 January 2018

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Selective allosteric coupling in core chemotaxis signaling complexes

21 January 2018

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Modified lipid and protein dynamics in nanodiscs

21 January 2018

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Active plasma membrane P-type H+-ATPase reconstituted into nanodiscs is a monomer.

21 January 2018

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Trimerization of the HIV Transmembrane Domain in Lipid Bilayers Modulates Broadly Neutralizing Antibody Binding

21 January 2018

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Nanodiscs as a Modular Platform for Multimodal MR-Optical Imaging

21 January 2018

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The photocycle and ultrafast vibrational dynamics of bacteriorhodopsin in lipid nanodiscs

21 January 2018

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The One-electron Autoxidation of Human Cytochrome P450 3A4

21 January 2018

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Cooperativity in Cytochrome P450 3A4

21 January 2018

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Assembly of single bacteriorhodopsin trimers in bilayer nanodiscs

21 January 2018

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The stability and activity of respiratory Complex II is cardiolipin-dependent

31 March 2020

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Helical rearrangement of photoactivated rhodopsin in monomeric and dimeric forms probed by high-angle X-ray scattering

31 March 2020

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Nanodiscs as a therapeutic delivery agent: inhibition of respiratory syncytial virus infection in the lung

31 March 2020

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27273631

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lipid-protein nanodiscs offer new perspectives for structural and functional studies of water-soluble membrane-active peptides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27273631

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.3195

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7 September 2017

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