Stimulation of EphB2 attenuates tau phosphorylation through PI3K/Akt-mediated inactivation of glycogen synthase kinase-3β. (Q38859228)

7 September 2017

Stimulation of EphB2 attenuates tau phosphorylation through PI3K/Akt-mediated inactivation of glycogen synthase kinase-3β. (English)

1 reference

7 September 2017

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6

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14 June 2020

author name string

Jun Jiang

1

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14 June 2020

Zhi-Hao Wang

2

1 reference

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14 June 2020

Min Qu

3

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14 June 2020

Di Gao

4

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14 June 2020

Xiu-Ping Liu

5

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14 June 2020

Jian-Zhi Wang

7

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14 June 2020

language of work or name

English

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publication date

29 June 2015

1 reference

7 September 2017

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14 June 2020

volume

5

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14 June 2020

page(s)

11765

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Creative Commons Attribution 4.0 International

14 June 2020

copyright license

start time

29 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

EphB2 activation is required for ependymoma development as well as inhibits differentiation and promotes proliferation of the transformed cell

1 reference

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EphB2 receptor forward signaling controls cortical growth cone collapse via Nck and Pak.

9 September 2017

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PI3K contributed to modulation of spinal nociceptive information related to ephrinBs/EphBs

9 September 2017

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Expression and Function of Ephrin-B1 and Its Cognate Receptor EphB2 in Human Abdominal Aortic Aneurysm

9 September 2017

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Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

9 September 2017

1 reference

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Peptide EphB2/CTF2 generated by the gamma-secretase processing of EphB2 receptor promotes tyrosine phosphorylation and cell surface localization of N-methyl-D-aspartate receptors.

9 September 2017

1 reference

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The role of GSK3 in Alzheimer disease.

9 September 2017

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EphB receptors couple dendritic filopodia motility to synapse formation

9 September 2017

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Microtubule-associated protein tau in development, degeneration and protection of neurons

9 September 2017

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Bidirectional Eph-ephrin signaling during axon guidance

9 September 2017

1 reference

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Phosphorylation of tau antagonizes apoptosis by stabilizing beta-catenin, a mechanism involved in Alzheimer's neurodegeneration

9 September 2017

1 reference

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Eph receptor signalling casts a wide net on cell behaviour

9 September 2017

1 reference

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Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators

9 September 2017

1 reference

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Ephrin signaling in vivo: look both ways

9 September 2017

1 reference

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Mechanisms and functions of Eph and ephrin signalling

9 September 2017

1 reference

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Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity

9 September 2017

1 reference

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Multiple roles of EPH receptors and ephrins in neural development

9 September 2017

1 reference

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EphB receptors interact with NMDA receptors and regulate excitatory synapse formation

9 September 2017

1 reference

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Protein tyrosine kinase structure and function

9 September 2017

1 reference

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Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Identifying transient protein-protein interactions in EphB2 signaling by blue native PAGE and mass spectrometry

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

GSK-3 beta inhibits presynaptic vesicle exocytosis by phosphorylating P/Q-type calcium channel and interrupting SNARE complex formation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Notch signaling promotes the generation of EphrinB1-positive intestinal epithelial cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Pre-synaptic and post-synaptic localization of EphA4 and EphB2 in adult mouse forebrain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Estradiol attenuates tau hyperphosphorylation induced by upregulation of protein kinase-A.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

17 June 2018

1 reference

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Disease-modified glycogen synthase kinase-3β intervention by melatonin arrests the pathology and memory deficits in an Alzheimer's animal model.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Reduction and the intracellular translocation of EphB2 in Tg2576 mice and the effects of β-amyloid

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Activation of glycogen synthase kinase-3 inhibits long-term potentiation with synapse-associated impairments

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Glycogen synthase kinase-3 plays a crucial role in tau exon 10 splicing and intranuclear distribution of SC35. Implications for Alzheimer's disease

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Alzheimer's neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Restoration of biological activity of Alzheimer abnormally phosphorylated tau by dephosphorylation with protein phosphatase-2A, -2B and -1.

22 August 2018

1 reference

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Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484244

Mutagenesis of Fujinami Sarcoma Virus: Evidence that tyrosine phosphorylation of P130gag-fps modulates its biological activity

22 August 2018

1 reference

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The pathological process underlying Alzheimer's disease in individuals under thirty

22 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26119563

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12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP11765

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119563%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

14 June 2020

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1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119563%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

PubMed publication ID

26119563

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119563%20AND%20SRC:MED&resulttype=core&format=json