Activation of the FGFR1 signalling pathway by the Epstein-Barr virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells. (Q38861579)

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English	Activation of the FGFR1 signalling pathway by the Epstein-Barr virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells.	scientific article

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17 February 2020

Activation of the FGFR1 signalling pathway by the Epstein-Barr virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells (English)

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17 February 2020

Epstein–Barr virus

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Lawrence S Young

3

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5

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17 February 2020

author name string

Angela Kwok-Fung Lo

1

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17 February 2020

Christopher W Dawson

2

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17 February 2020

Chuen-Wai Ko

4

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17 February 2020

Kwok-Wai Lo

6

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publication date

3 August 2015

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17 February 2020

Journal of Pathology

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17 February 2020

237

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238-248

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2

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17 February 2020

The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC).

1 reference

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21 January 2018

Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches

1 reference

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The significance of LMP1 expression in nasopharyngeal carcinoma

1 reference

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Regulation of cancer cell metabolism

1 reference

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Roles of p53, MYC and HIF-1 in regulating glycolysis - the seventh hallmark of cancer

1 reference

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Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

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Post-translational modifications and the Warburg effect

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21 January 2018

De-regulated FGF receptors as therapeutic targets in cancer

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Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells

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21 January 2018

Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism

1 reference

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21 January 2018

Epstein-Barr virus infection alters cellular signal cascades in human nasopharyngeal epithelial cells

1 reference

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21 January 2018

Inhibition of the LKB1-AMPK pathway by the Epstein-Barr virus-encoded LMP1 promotes proliferation and transformation of human nasopharyngeal epithelial cells

1 reference

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21 January 2018

Phenotypic alterations induced by the Hong Kong-prevalent Epstein-Barr virus-encoded LMP1 variant (2117-LMP1) in nasopharyngeal epithelial cells

1 reference

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21 January 2018

Emerging roles of PKM2 in cell metabolism and cancer progression

1 reference

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21 January 2018

Targeting Epstein-Barr virus oncoprotein LMP1-mediated glycolysis sensitizes nasopharyngeal carcinoma to radiation therapy

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21 January 2018

IKKβ and NF-κB transcription govern lymphoma cell survival through AKT-induced plasma membrane trafficking of GLUT1.

1 reference

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21 January 2018

c-Myc and EBV-LMP1: two opposing regulators of the HLA class I antigen presentation machinery in epithelial cells

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21 January 2018

EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells

1 reference

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21 January 2018

A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-Barr virus.

1 reference

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21 January 2018

Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha

1 reference

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21 January 2018

Latent membrane protein 1 of Epstein-Barr virus coordinately regulates proliferation with control of apoptosis.

1 reference

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21 January 2018

Modulation of LMP1 protein expression by EBV-encoded microRNAs

1 reference

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21 January 2018

Fibroblast growth factor receptors, developmental corruption and malignant disease

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21 January 2018

Role of FGF receptors as an emerging therapeutic target in lung squamous cell carcinoma.

1 reference

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21 January 2018

Epstein-Barr virus immortalization of human B-cells leads to stabilization of hypoxia-induced factor 1 alpha, congruent with the Warburg effect

1 reference

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21 January 2018

Metabolism and proliferation share common regulatory pathways in cancer cells

1 reference

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21 January 2018

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

1 reference

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21 January 2018

Sp1 is required for transcriptional activation of the fibroblast growth factor receptor 1 gene in neonatal cardiomyocytes.

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21 January 2018

Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-1.

1 reference

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21 January 2018

Sp1 phosphorylation and its regulation of gene transcription.

1 reference

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21 January 2018

Induction of Id1 and Id3 by latent membrane protein 1 of Epstein-Barr virus and regulation of p27/Kip and cyclin-dependent kinase 2 in rodent fibroblast transformation

1 reference

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21 January 2018

Unique signaling properties of CTAR1 in LMP1-mediated transformation

1 reference

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21 January 2018

LMP1 strain variants: biological and molecular properties.

1 reference

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21 January 2018

Nuclear epidermal growth factor receptor interacts with transcriptional intermediary factor 2 to activate cyclin D1 gene expression triggered by the oncoprotein latent membrane protein 1.

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21 January 2018

Epstein-Barr Virus encoded LMP1 regulates cyclin D1 promoter activity by nuclear EGFR and STAT3 in CNE1 cells

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21 January 2018

Epstein-Barr virus latent membrane protein 1 (CAO) up-regulates VEGF and TGF alpha concomitant with hyperlasia, with subsequent up-regulation of p16 and MMP9.

1 reference

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21 January 2018

The pathological roles of BART miRNAs in nasopharyngeal carcinoma

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21 January 2018

FGFR signalling in women's cancers

1 reference

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Identifiers

10.1002/PATH.4575

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26096068%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26096068%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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