Human anti-CAIX antibodies mediate immune cell inhibition of renal cell carcinoma in vitro and in a humanized mouse model in vivo (Q38865279)

7 September 2017

Human anti-CAIX antibodies mediate immune cell inhibition of renal cell carcinoma in vitro and in a humanized mouse model in vivo (English)

1 reference

7 September 2017

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5

Sabina Signoretti

1 reference

7 September 2017

De-Kuan Chang

1

1 reference

7 September 2017

Raymond J Moniz

2

1 reference

7 September 2017

Zhongyao Xu

3

1 reference

7 September 2017

Jiusong Sun

4

1 reference

7 September 2017

Quan Zhu

6

1 reference

7 September 2017

Wayne A Marasco

7

1 reference

7 September 2017

language of work or name

1 reference

11 June 2015

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7 September 2017

1 reference

7 September 2017

14

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7 September 2017

119

1 reference

Creative Commons Attribution 4.0 International

7 September 2017

start time

11 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/s12943-015-0384-3

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cites work

Immunotherapeutic strategies for the treatment of renal cell carcinoma: where are we now?

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Application of monoclonal antibody G250 recognizing carbonic anhydrase IX in renal cell carcinoma

9 September 2017

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Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: clinical evaluation and management of on-target toxicity

9 September 2017

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Humanization of an anti-CCR4 antibody that kills cutaneous T-cell lymphoma cells and abrogates suppression by T-regulatory cells

9 September 2017

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A validated tumorgraft model reveals activity of dovitinib against renal cell carcinoma

9 September 2017

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Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

9 September 2017

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9 September 2017

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Patient-derived tumour xenografts as models for oncology drug development

9 September 2017

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Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy

9 September 2017

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Immunological heterogeneity of the RCC microenvironment: do targeted therapies influence immune response?

9 September 2017

1 reference

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Human allograft rejection in humanized mice: a historical perspective

9 September 2017

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Recent developments in targeting carbonic anhydrase IX for cancer therapeutics

9 September 2017

1 reference

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Targeted therapies for renal cell carcinoma: review of adverse event management strategies

9 September 2017

1 reference

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Therapeutic mechanism and efficacy of the antibody-drug conjugate BAY 79-4620 targeting human carbonic anhydrase 9.

9 September 2017

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Targeted therapies in metastatic renal cell carcinoma: overview of the past year

9 September 2017

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Interfering with pH regulation in tumours as a therapeutic strategy

9 September 2017

1 reference

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Therapeutic vaccines in renal cell carcinoma

9 September 2017

1 reference

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The epidemiology of renal cell carcinoma.

9 September 2017

1 reference

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Orthotopic xenografts of RCC retain histological, immunophenotypic and genetic features of tumours in patients

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Inhibition of angiogenic and non-angiogenic targets by sorafenib in renal cell carcinoma (RCC) in a RCC xenograft model

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX.

9 September 2017

1 reference

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Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Carbonic anhydrase 9 in clear cell renal cell carcinoma: a marker for diagnosis, prognosis and treatment

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Complement and its role in innate and adaptive immune responses

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Vaccine therapy in patients with renal cell carcinoma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Carbonic anhydrase IX and renal cell carcinoma: prognosis, response to systemic therapy, and future vaccine strategies

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

PD-1 and its ligands in tolerance and immunity

9 September 2017

1 reference

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Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

9 September 2017

1 reference

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A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.

9 September 2017

1 reference

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Humanized mice in translational biomedical research

9 September 2017

1 reference

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Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

FcgammaRIV: a novel FcR with distinct IgG subclass specificity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Fc receptors are required in passive and active immunity to melanoma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Genetic and pathogenic basis of autoimmune diabetes in NOD mice

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Immune checkpoint inhibitors as novel targets for renal cell carcinoma therapeutics

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Carbonic anhydrase IX interacts with bicarbonate transporters in lamellipodia and increases cell migration via its catalytic domain.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Signal transduction during natural killer cell activation: inside the mind of a killer

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Development and characterization of clinically relevant tumor models from patients with renal cell carcinoma.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

A clinical phase I/II trial with the monoclonal antibody cG250 (RENCAREX®) and interferon-alpha-2a in metastatic renal cell carcinoma patients

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Soluble form of carbonic anhydrase IX (CAIX) in transitional cell carcinoma of urinary tract.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

HIF-1alpha and CA IX staining in invasive breast carcinomas: prognosis and treatment outcome.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Expression of carbonic anhydrase IX in breast is associated with malignant tissues and is related to overexpression of c-erbB2.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464115

Regression of established renal cell carcinoma in nude mice using lentivirus-transduced human T cells expressing a human anti-CAIX chimeric antigen receptor

22 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12943-015-0384-3

Hypoxia-Inducible Factor-1 Expression Predicts a Poor Response to Primary Chemoendocrine Therapy and Disease-Free Survival in Primary Human Breast Cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12943-015-0384-3

A clinical trial with chimeric monoclonal antibody WX-G250 and low dose interleukin-2 pulsing scheme for advanced renal cell carcinoma

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26062742

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26062742

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S12943-015-0384-3

1 reference

Dimensions Publication ID

7 September 2017

0 references

1 reference

7 September 2017

1 reference