Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL. (Q38908846)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25688158%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL (English)

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1 March 2020

11

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1 March 2020

Janna Minehart

6

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1 March 2020

Matthew Witkin

7

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1 March 2020

author name string

Matthew C Stubbs

1

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1 March 2020

Wonil Kim

2

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1 March 2020

Megan Bariteau

3

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1 March 2020

Tina Davis

4

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1 March 2020

Sridhar Vempati

5

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1 March 2020

Jun Qi

8

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1 March 2020

Andrei V Krivtsov

9

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James E Bradner

10

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1 March 2020

Scott A Armstrong

12

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1 March 2020

language of work or name

English

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publication date

16 February 2015

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1 March 2020

published in

Clinical Cancer Research

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1 March 2020

volume

21

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issue

10

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1 March 2020

page(s)

2348-2358

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A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests

1 March 2020

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Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

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Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability

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Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair.

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Downregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factor

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9 September 2017

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CBP/p300-mediated acetylation of histone H3 on lysine 56

9 September 2017

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Development of vorinostat: current applications and future perspectives for cancer therapy

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Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization

9 September 2017

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HOXA9 is required for survival in human MLL-rearranged acute leukemias

9 September 2017

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H3K79 methylation profiles define murine and human MLL-AF4 leukemias

9 September 2017

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Histone deacetylase inhibitors in cancer therapy: new compounds and clinical update of benzamide-type agents

9 September 2017

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Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

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9 September 2017

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9 September 2017

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9 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Use of a novel histone deacetylase inhibitor to induce apoptosis in cell lines of acute lymphoblastic leukemia.

14 September 2017

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HDACs link the DNA damage response, processing of double-strand breaks and autophagy

14 September 2017

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Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia

17 June 2018

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Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice

22 August 2018

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Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2).

22 August 2018

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Histone deacetylase inhibitors (HDI) cause DNA damage in leukemia cells: a mechanism for leukemia-specific HDI-dependent apoptosis?

22 August 2018

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FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases

22 August 2018

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10.1158/1078-0432.CCR-14-1290

22 August 2018

Identifiers

DOI

1 reference

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1 March 2020

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1 March 2020

PubMed publication ID

25688158

1 reference