Histone deacetylases and cancer (Q28240447)

GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer

Europe PubMed Central

title

Histone deacetylases and cancer (English)

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author name string

M A Glozak

series ordinal

1

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E Seto

series ordinal

2

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language of work or name

English

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publication date

13 August 2007

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published in

Oncogene

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volume

26

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issue

37

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page(s)

5420-32

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cites work

1 reference

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ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

21 April 2017

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Retinoblastoma protein recruits histone deacetylase to repress transcription

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Duration of nuclear NF-kappaB action regulated by reversible acetylation

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Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.

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Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

21 April 2017

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The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain

21 April 2017

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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

21 April 2017

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Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 April 2017

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The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3

21 April 2017

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Histone deacetylase activity is required for full transcriptional repression by mSin3A

21 April 2017

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HDAC6 is a microtubule-associated deacetylase

21 April 2017

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MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

21 April 2017

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Translating the Histone Code

21 April 2017

1 reference

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Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210610

Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65

21 April 2017

1 reference

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HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor

21 April 2017

1 reference

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Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

21 April 2017

1 reference

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Class II histone deacetylases are directly recruited by BCL6 transcriptional repressor

21 April 2017

1 reference

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Negative control of p53 by Sir2alpha promotes cell survival under stress

21 April 2017

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Rb interacts with histone deacetylase to repress transcription

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210610

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

21 April 2017

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In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

21 April 2017

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The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210610

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210610

Tumor suppressor SMAR1 mediates cyclin D1 repression by recruitment of the SIN3/histone deacetylase 1 complex

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210610

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210610

A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210610

A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210610

SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210610

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210610

Colorectal cancer in mice genetically deficient in the mucin Muc2

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210610

Altered interaction of HDAC5 with GATA-1 during MEL cell differentiation

21 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1210610

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210610

Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210610

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210610

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210610

Acetylation and deacetylation of non-histone proteins

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

Acetylation: a regulatory modification to rival phosphorylation?

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

Histone H4-K16 acetylation controls chromatin structure and protein interactions

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

Modification of the phenotype of murine sarcoma virus-transformed cells by sodium butyrate. Effects on morphology and cytoskeletal elements

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Restoration of transforming growth factor-beta signaling through receptor RI induction by histone deacetylase activity inhibition in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Peroxisome proliferator-activated receptor gamma regulates E-cadherin expression and inhibits growth and invasion of prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Repression of MUC2 gene expression by butyrate, a physiological regulator of intestinal cell maturation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Acetylation inactivates the transcriptional repressor BCL6.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Regulation of activity of the transcription factor GATA-1 by acetylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Histone modifications silence the GATA transcription factor genes in ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

ETO protein of t(8;21) AML is a corepressor for Bcl-6 B-cell lymphoma oncoprotein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Histone deacetylase inhibitors potently repress CXCR4 chemokine receptor expression and function in acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Epigenetic consequences of AML1-ETO action at the human c-FMS locus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Growth inhibition and morphological changes caused by lipophilic acids in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Nuclear factor-kappaB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-kappaB-dependent transcription in cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Adenomatous polyposis coli determines sensitivity to histone deacetylase inhibitor-induced apoptosis in colon cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

CREB-Binding protein acetylates hematopoietic transcription factor GATA-1 at functionally important sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Smad3 is acetylated by p300/CBP to regulate its transactivation activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Apicidin is a histone deacetylase inhibitor with anti-invasive and anti-angiogenic potentials

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Acetylation of Stat1 modulates NF-kappaB activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Acetylation of GATA-1 is required for chromatin occupancy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Invasion of v-Fos(FBR)-transformed cells is dependent upon histone deacetylase activity and suppression of histone deacetylase regulated genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Valproic acid inhibits angiogenesis in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Histone deacetylase inhibitors radiosensitize human melanoma cells by suppressing DNA repair activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Stat3 activation of NF-{kappa}B p100 processing involves CBP/p300-mediated acetylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Site-specific acetylation of p53 directs selective transcription complex assembly.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

DNA damage activates p53 through a phosphorylation-acetylation cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

RUNX3 protein is overexpressed in human basal cell carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

An acetylation site in the middle domain of Hsp90 regulates chaperone function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Global histone modification patterns predict risk of prostate cancer recurrence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Increased expression of histone deacetylase 2 is found in human gastric cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Acetylation of the p53 DNA-binding domain regulates apoptosis induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

The histone deacetylase-3 complex contains nuclear receptor corepressors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Regulation of tissue-specific and extracellular matrix-related genes by a class I histone deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

AML1 is functionally regulated through p300-mediated acetylation on specific lysine residues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Histone deacetylase inhibitors induce the degradation of the t(8;21) fusion oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Stat3 dimerization regulated by reversible acetylation of a single lysine residue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Two catalytic domains are required for protein deacetylation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210610

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210610

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1734261

1023418889

0 references

1734261

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference