The MAP kinase-interacting kinases regulate cell migration, vimentin expression and eIF4E/CYFIP1 binding (Q38920048)

7 September 2017

title

The MAP kinase-interacting kinases regulate cell migration, vimentin expression and eIF4E/CYFIP1 binding (English)

1 reference

7 September 2017

8

1 reference

7 September 2017

Valentina Iadevaia

5

0 references

Jianling Xie

object named as

Jianling Xie

4

0 references

author name string

James E Beggs

1

1 reference

7 September 2017

Shuye Tian

2

1 reference

7 September 2017

Greg G Jones

3

1 reference

7 September 2017

Veronika Jenei

6

1 reference

7 September 2017

Gareth Thomas

7

1 reference

7 September 2017

language of work or name

English

0 references

publication date

1 April 2015

1 reference

7 September 2017

1 reference

7 September 2017

volume

467

1 reference

7 September 2017

issue

1

1 reference

7 September 2017

page(s)

63-76

1 reference

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

7 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases).

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Cap in hand: targeting eIF4E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Influence of electric charge variation at residues 209 and 159 on the interaction of eIF4E with the mRNA 5' terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Targeting Mnks for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

MAP kinase-interacting kinase 1 regulates SMAD2-dependent TGF-β signaling pathway in human glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

FMRP targets distinct mRNA sequence elements to regulate protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

The fragile X protein binds mRNAs involved in cancer progression and modulates metastasis formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Impairing the production of ribosomal RNA activates mammalian target of rapamycin complex 1 signalling and downstream translation factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

alpha v beta 6 Integrin upregulates matrix metalloproteinase 9 and promotes migration of normal oral keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Rapamycin enhances eIF4E phosphorylation by activating MAP kinase-interacting kinase 2a (Mnk2a).

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

The selectivity of protein kinase inhibitors: a further update

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

MNK1 pathway activity maintains protein synthesis in rapalog-treated gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Epithelial to mesenchymal transition in human skin wound healing is induced by tumor necrosis factor-alpha through bone morphogenic protein-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Epithelial-mesenchymal transitions in tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

The Role of Snail in EMT and Tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Complex networks orchestrate epithelial-mesenchymal transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Regulation of vimentin by SIP1 in human epithelial breast tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

WASP and SCAR/WAVE proteins: the drivers of actin assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Targeting the MAPK-RAS-RAF signaling pathway in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Fragile X mental retardation protein regulates translation by binding directly to the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

mRNA encoding WAVE-Arp2/3-associated proteins is co-localized with foci of active protein synthesis at the leading edge of MRC5 fibroblasts during cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

First MNKs degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

Essential role for Mnk kinases in type II interferon (IFNgamma) signaling and its suppressive effects on normal hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20141066

21 January 2018

Identifiers

DOI

10.1042/BJ20141066

1 reference

7 September 2017

1 reference