Cloning, heterologous expression, and substrate specificities of protein farnesyltransferases from Trypanosoma cruzi and Leishmania major (Q38924927)

7 September 2017

title

Cloning, heterologous expression, and substrate specificities of protein farnesyltransferases from Trypanosoma cruzi and Leishmania major (English)

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7 September 2017

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Leishmania major

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5

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1

Frederick S Buckner

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7 September 2017

2

Richard T Eastman

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7 September 2017

author name string

José L Nepomuceno-Silva

3

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7 September 2017

Emily C Speelmon

4

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Wesley C Van Voorhis

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7 September 2017

Kohei Yokoyama

7

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7 September 2017

language of work or name

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1 July 2002

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Molecular and Biochemical Parasitology

7 September 2017

published in

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7 September 2017

volume

122

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7 September 2017

issue

2

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page(s)

181-188

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Protein isoprenylation in Trypanosoma brucei brucei

7 September 2017

cites work

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Protein prenyl transferase activities of Plasmodium falciparum

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Isoprenylation of proteins in the protozoan Giardia lamblia

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7 January 2021

Role of protein modification reactions in programming interactions between ras-related GTPases and cell membranes

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7 January 2021

Protein prenylation: molecular mechanisms and functional consequences

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7 January 2021

The effects of protein farnesyltransferase inhibitors on trypanosomatids: inhibition of protein farnesylation and cell growth

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7 January 2021

Protein farnesyltransferase from Trypanosoma brucei. A heterodimer of 61- and 65-kda subunits as a new target for antiparasite therapeutics

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7 January 2021

Blocking oncogenic Ras signaling for cancer therapy

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7 January 2021

Farnesyltransferase inhibitors: potential role in the treatment of cancer

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7 January 2021

Cloning, heterologous expression, and distinct substrate specificity of protein farnesyltransferase from Trypanosoma brucei

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7 January 2021

Fl-160. A surface antigen of Trypanosoma cruzi that mimics mammalian nervous tissue

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Consensus-degenerate hybrid oligonucleotide primers for amplification of distantly related sequences

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Virulence in Trypanosoma cruzi infection correlates with the expression of a distinct family of sialidase superfamily genes

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7 January 2021

A physical map of the Leishmania major Friedlin genome

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7 January 2021

Leishmania major Friedlin chromosome 1 has an unusual distribution of protein-coding genes

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7 January 2021

TcRho1, a farnesylated Rho family homologue from Trypanosoma cruzi: cloning, trans-splicing, and prenylation studies

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7 January 2021

Isoprenoid diphosphate utilization by recombinant human farnesyl:protein transferase: interactive binding between substrates and a preferred kinetic pathway.

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7 January 2021

A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity

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7 January 2021

Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue

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7 January 2021

Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity

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7 January 2021

Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution

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7 January 2021

Amino acid substitutions that convert the protein substrate specificity of farnesyltransferase to that of geranylgeranyltransferase type I.

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7 January 2021

Ras farnesyltransferase: a new therapeutic target

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7 January 2021

Current status of clinical trials of farnesyltransferase inhibitors.

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7 January 2021

10.1016/S0166-6851(02)00099-3

Identifiers

DOI

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7 September 2017

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