Hispidulin inhibits proliferation and enhances chemosensitivity of gallbladder cancer cells by targeting HIF-1α. (Q38929424)

7 September 2017

Hispidulin inhibits proliferation and enhances chemosensitivity of gallbladder cancer cells by targeting HIF-1α. (English)

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7 September 2017

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Hui Gao

1

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7 September 2017

Jing Xie

2

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7 September 2017

Jianjun Peng

3

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7 September 2017

Yantao Han

4

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7 September 2017

Qixiao Jiang

5

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7 September 2017

Mei Han

6

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7 September 2017

Chunbo Wang

7

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7 September 2017

language of work or name

English

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publication date

8 December 2014

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Experimental Cell Research

7 September 2017

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7 September 2017

332

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7 September 2017

2

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7 September 2017

236-246

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Diagnosis and surgical management of gallbladder cancer: a review

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Expression of hypoxia-inducible factor-1 alpha (HIF-1alpha) in patients with the gallbladder carcinoma.

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Inhibition of epidermal growth factor receptor signaling by Saussurea involucrata, a rare traditional Chinese medicinal herb, in human hormone-resistant prostate cancer PC-3 cells

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The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects

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Hispidulin exerts anti-osteoporotic activity in ovariectomized mice via activating AMPK signaling pathway.

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Hispidulin attenuates bone resorption and osteoclastogenesis via the RANKL-induced NF-κB and NFATc1 pathways.

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Hispidulin sensitizes human ovarian cancer cells to TRAIL-induced apoptosis by AMPK activation leading to Mcl-1 block in translation

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Hispidulin potently inhibits human glioblastoma multiforme cells through activation of AMP-activated protein kinase (AMPK).

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Hispidulin, a small flavonoid molecule, suppresses the angiogenesis and growth of human pancreatic cancer by targeting vascular endothelial growth factor receptor 2-mediated PI3K/Akt/mTOR signaling pathway.

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Potential Therapeutic Role of Hispidulin in Gastric Cancer through Induction of Apoptosis via NAG-1 Signaling

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Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells

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Icariin potentiates the antitumor activity of gemcitabine in gallbladder cancer by suppressing NF-κB

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Mitochondrial dysfunction represses HIF-1α protein synthesis through AMPK activation in human hepatoma HepG2 cells.

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Cordycepin down-regulates multiple drug resistant (MDR)/HIF-1α through regulating AMPK/mTORC1 signaling in GBC-SD gallbladder cancer cells

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Recent advances in systemic therapies and radiotherapy for gallbladder cancer

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Dietary flavonoids as cancer prevention agents

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HIF-1α knockdown by miRNA decreases survivin expression and inhibits A549 cell growth in vitro and in vivo

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Apigenin down-regulates the hypoxia response genes: HIF-1α, GLUT-1, and VEGF in human pancreatic cancer cells

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Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis.

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Knockdown of hypoxia-inducible factor-1alpha in breast carcinoma MCF-7 cells results in reduced tumor growth and increased sensitivity to methotrexate

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10.1016/J.YEXCR.2014.11.021

7 January 2021

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DOI

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7 September 2017

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