Endothelial-targeted Gene Transfer of Hypoxia-inducible Factor-1α Augments Ischemic Neovascularization Following Systemic Administration (Q38966065)

8 September 2017

title

Endothelial-targeted Gene Transfer of Hypoxia-inducible Factor-1α Augments Ischemic Neovascularization Following Systemic Administration (English)

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8 September 2017

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2

Aviv Shaish

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7

Iris Barshack

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6

Arnon Afek

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8 September 2017

Reshef Tal

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8 September 2017

Karen Rofe

3

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8 September 2017

Erez Feige

4

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Nira Varda-Bloom

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8 September 2017

Livnat Bangio

8

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8 September 2017

Israel Hodish

9

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Shoshana Greenberger

10

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Michael Peled

11

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Eyal Breitbart

12

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8 September 2017

Dror Harats

13

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8 September 2017

publication date

1 December 2008

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8 September 2017

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8 September 2017

volume

16

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8 September 2017

issue

12

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8 September 2017

page(s)

1927-1936

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Therapeutic angiogenesis and vasculogenesis for ischemic disease. Part I: angiogenic cytokines

8 September 2017

cites work

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7 January 2021

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Regional Angiogenesis with Vascular Endothelial Growth Factor (VEGF) in peripheral arterial disease: Design of the RAVE trial

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A conserved family of prolyl-4-hydroxylases that modify HIF

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7 January 2021

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

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7 January 2021

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

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7 January 2021

Intramyocardial injection of naked DNA encoding HIF-1alpha/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat.

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7 January 2021

Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1alpha/VP16 hybrid transcription factor

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7 January 2021

Constitutively active HIF-1alpha improves perfusion and arterial remodeling in an endovascular model of limb ischemia

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7 January 2021

Stabilized HIF-1alpha is superior to VEGF for angiogenesis in skeletal muscle via adeno-associated virus gene transfer

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7 January 2021

Use of a constitutively active hypoxia-inducible factor-1alpha transgene as a therapeutic strategy in no-option critical limb ischemia patients: phase I dose-escalation experience

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OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

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7 January 2021

Activation of C-transactivation domain is essential for optimal HIF-1 alpha-mediated transcriptional and angiogenic effects

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7 January 2021

Gene transfer as a tool to induce therapeutic vascular growth

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7 January 2021

Biodistribution of an adenoviral vector carrying the luciferase reporter gene following intravesical or intravenous administration to a mouse

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7 January 2021

Angiopoietin-1 protects the adult vasculature against plasma leakage.

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7 January 2021

Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter

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7 January 2021

Tissue-specific gene therapy directed to tumor angiogenesis.

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7 January 2021

Endothelial cell-specific transcriptional targeting from a hybrid long terminal repeat retrovirus vector containing human prepro-endothelin-1 promoter sequences

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7 January 2021

Transcription-controlled gene therapy against tumor angiogenesis.

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7 January 2021

Antiangiogenic systemic gene therapy combined with doxorubicin administration induced caspase 8 and 9-mediated apoptosis in endothelial cells and an anti-metastasis effect.

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7 January 2021

Vascular wall maturation and prolonged angiogenic effect by endothelial-specific platelet-derived growth factor expression

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7 January 2021

Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo

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7 January 2021

Analysis of cell-specific promoters for viral gene therapy targeted at the vascular endothelium

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7 January 2021

A novel combination of promoter and enhancers increases transgene expression in vascular smooth muscle cells in vitro and coronary arteries in vivo after adenovirus-mediated gene transfer

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https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Transcriptional targeting of replication-defective adenovirus transgene expression to smooth muscle cells in vivo.

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https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies

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https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

A targetable, injectable adenoviral vector for selective gene delivery to pulmonary endothelium in vivo

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7 January 2021

Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105).

1 reference

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7 January 2021

Development of efficient viral vectors selective for vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Identification of an endothelial cell-specific regulatory region in the murine endothelin-1 gene

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

CoCl2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Hypoxia stimulates proliferation of human hepatoma cells through the induction of hexokinase II expression.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Brain-specific knock-out of hypoxia-inducible factor-1alpha reduces rather than increases hypoxic-ischemic damage.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Impaired collateral vessel development associated with reduced expression of vascular endothelial growth factor in ApoE-/- mice

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Angiogenic gene therapy for experimental critical limb ischemia: acceleration of limb loss by overexpression of vascular endothelial growth factor 165 but not of fibroblast growth factor-2.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Gene transfer of stromal cell-derived factor-1alpha enhances ischemic vasculogenesis and angiogenesis via vascular endothelial growth factor/endothelial nitric oxide synthase-related pathway: next-generation chemokine therapy for therapeutic neovasc

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Salvage angiogenesis induced by adenovirus-mediated gene transfer of vascular endothelial growth factor protects against ischemic vascular occlusion

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Role of inflammatory mediators in angiogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.191

7 January 2021

Identifiers

DOI

10.1038/MT.2008.191

1 reference

release_idp3vcuy7nhq7kmipzj64wmfdy

8 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/idp3vcuy7nhq7kmipzj64wmfdy

24 November 2022

mapped directly with Wikidata item

1 reference