Application of bee venom and its main constituent melittin for cancer treatment (Q38966140)

8 September 2017

1 reference

title

Application of bee venom and its main constituent melittin for cancer treatment (English)

1 reference

8 September 2017

0 references

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Cui-Cui Liu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Qian Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Jing An

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Jing-Jing Zhao

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Bo Chen

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Ling-Ling Zhang

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Hao Yang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

27 September 2016

1 reference

Cancer Chemotherapy and Pharmacology

8 September 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

78

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

1113-1130

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012

1 June 2020

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Enhanced anticancer efficacy of snake venom combined with silica nanoparticles in a murine model of human multiple myeloma: molecular targets for cell cycle arrest and apoptosis induction.

21 January 2018

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Review of the anticancer activities of bee products

21 January 2018

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Potentiation of anticancer-drug cytotoxicity by sea anemone pore-forming proteins in human glioblastoma cells

21 January 2018

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Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: melittin, apamin and mastoparan

21 January 2018

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Melittin has a chondroprotective effect by inhibiting MMP-1 and MMP-8 expressions via blocking NF-κB and AP-1 signaling pathway in chondrocytes.

21 January 2018

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Bee venom acupuncture for rheumatoid arthritis: a systematic review of randomised clinical trials

21 January 2018

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Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds

21 January 2018

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Effect of polypeptides in bee venom on growth inhibition and apoptosis induction of the human hepatoma cell line SMMC-7721 in-vitro and Balb/c nude mice in-vivo

21 January 2018

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Anti-cancer effect of bee venom in prostate cancer cells through activation of caspase pathway via inactivation of NF-κB.

21 January 2018

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Honeybee venom induces calcium-dependent but caspase-independent apoptotic cell death in human melanoma A2058 cells

21 January 2018

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Bee venom induces apoptosis and inhibits expression of cyclooxygenase-2 mRNA in human lung cancer cell line NCI-H1299.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Bee venom induces apoptosis through intracellular Ca2+ -modulated intrinsic death pathway in human bladder cancer cells

21 January 2018

1 reference

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Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Cancer cell growth inhibitory effect of bee venom via increase of death receptor 3 expression and inactivation of NF-kappa B in NSCLC cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Inhibition of mammary carcinoma cell proliferation in vitro and tumor growth in vivo by bee venom.

21 January 2018

1 reference

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Effect of honey bee venom on proliferation of K1735M2 mouse melanoma cells in-vitro and growth of murine B16 melanomas in-vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Co-culture with NK-92MI cells enhanced the anti-cancer effect of bee venom on NSCLC cells by inactivation of NF-κB.

21 January 2018

1 reference

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21 January 2018

1 reference

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Antimicrobial peptide melittin against Xanthomonas oryzae pv. oryzae, the bacterial leaf blight pathogen in rice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Cationic membrane-active peptides - anticancer and antifungal activity as well as penetration into human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Perspective of Use of Antiviral Peptides against Influenza Virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin induces in vitro death of Leishmania (Leishmania) infantum by triggering the cellular innate immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin peptide kills Trypanosoma cruzi parasites by inducing different cell death pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin: a lytic peptide with anticancer properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Site of fluorescent label modifies interaction of melittin with live cells and model membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Mechanism of membrane damage induced by the amphipathic peptides gramicidin S and melittin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin exerts multiple effects on the release of free fatty acids from L1210 cells: lack of selective activation of phospholipase A2 by melittin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin triggers apoptosis in Candida albicans through the reactive oxygen species-mediated mitochondria/caspase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin peptides exhibit different activity on different cells and model membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Cationic amphiphilic peptides with cancer-selective toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

The membrane-lytic peptides K8L9 and melittin enter cancer cells via receptor endocytosis following subcytotoxic exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Bee venom in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Apoptosis: a review of programmed cell death

21 January 2018

1 reference

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Ion channels in the regulation of apoptosis.

21 January 2018

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Selective inhibitors of Bcl-2 and Bcl-xL: Balancing antitumor activity with on-target toxicity

21 January 2018

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Apoptosis: programmed cell death at a molecular level

21 January 2018

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Mitochondrial control of apoptosis: an introduction

21 January 2018

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Major apoptotic mechanisms and genes involved in apoptosis

21 January 2018

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Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

21 January 2018

1 reference

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Mitochondrial calcium signalling and cell death: approaches for assessing the role of mitochondrial Ca2+ uptake in apoptosis

21 January 2018

1 reference

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A historical review of cellular calcium handling, with emphasis on mitochondria.

21 January 2018

1 reference

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Phospholipase A2-independent Ca2+ entry and subsequent apoptosis induced by melittin in human MG63 osteosarcoma cells

21 January 2018

1 reference

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Inhibition of growth of C6 astrocytoma cells by inhibitors of calmodulin

21 January 2018

1 reference

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Melittin induces human gastric cancer cell apoptosis via activation of mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Modulation of death receptors by cancer therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IkappaBalpha kinase-NFkap

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin induces Bcl-2 and caspase-3-dependent apoptosis through downregulation of Akt phosphorylation in human leukemic U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Two E-selectin ligands, BST-2 and LGALS3BP, predict metastasis and poor survival of ER-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Gene products which play a role in cancer invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin prevents liver cancer cell metastasis through inhibition of the Rac1-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin has an inhibitory effect on TNF-α-induced migration of human aortic smooth muscle cells by blocking the MMP-9 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin suppresses EGF-induced cell motility and invasion by inhibiting PI3K/Akt/mTOR signaling pathway in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin suppresses PMA-induced tumor cell invasion by inhibiting NF-kappaB and AP-1-dependent MMP-9 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin suppresses VEGF-A-induced tumor growth by blocking VEGFR-2 and the COX-2-mediated MAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin suppresses HIF-1α/VEGF expression through inhibition of ERK and mTOR/p70S6K pathway in human cervical carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Cell Cycle Regulation and Melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin induces PTCH1 expression by down-regulating MeCP2 in human hepatocellular carcinoma SMMC-7721 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin restores PTEN expression by down-regulating HDAC2 in human hepatocelluar carcinoma HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Potentiation of bleomycin lethality in HeLa and V79 cells by bee venom

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin radiosensitizes esophageal squamous cell carcinoma with induction of apoptosis in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Dissection of antibacterial and toxic activity of melittin: a leucine zipper motif plays a crucial role in determining its hemolytic activity but not antibacterial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Antigen binding and cytotoxic properties of a recombinant immunotoxin incorporating the lytic peptide, melittin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Hybrid melittin cytolytic Peptide-driven ultrasmall lipid nanoparticles block melanoma growth in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Eukaryotic expression vectors bearing genes encoding cytotoxic proteins for cancer gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

First-in-man phase 1 clinical trial of gene therapy for advanced pancreatic cancer: safety, biodistribution, and preliminary clinical findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Inhibitory effect of recombinant adenovirus carrying melittin gene on hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Cytotoxic properties of immunoconjugates containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Construction and characterization of an anti-asialoglycoprotein receptor single-chain variable-fragment-targeted melittin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Enhanced binding to and killing of hepatocellular carcinoma cells in vitro by melittin when linked with a novel targeting peptide screened from phage display

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Melittin-MIL-2 fusion protein as a candidate for cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Nanoparticle-mediated delivery of suicide genes in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Synthesis and characterization of stable fluorocarbon nanostructures as drug delivery vehicles for cytolytic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Cytolytic peptide nanoparticles ('NanoBees') for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Delivery of a Protease-Activated Cytolytic Peptide Prodrug by Perfluorocarbon Nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Synthesis and preliminary evaluation of poly(amidoamine)-melittin conjugates as endosomolytic polymers and/or potential anticancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Poly(I:C)-mediated tumor growth suppression in EGF-receptor overexpressing tumors using EGF-polyethylene glycol-linear polyethylenimine as carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Defined nanoscale chemistry influences delivery of peptido-toxins for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

RGD-modified lipid disks as drug carriers for tumor targeted drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Design of high payload PLGA nanoparticles containing melittin/sodium dodecyl sulfate complex by the hydrophobic ion-pairing technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Oncolytic activities of host defense peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

Suicide cancer gene therapy using pore-forming toxin, streptolysin O.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-016-3160-1

10.1007/S00280-016-3160-1

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677623%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 June 2020

1022554337

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Fatcat ID

release_ltk7cmo37jdfxemwdyiucmrcxe

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https://api.fatcat.wiki/v0/release/ltk7cmo37jdfxemwdyiucmrcxe

mapped directly with Wikidata item

24 November 2022

based on heuristic

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