Decitabine induces delayed reactive oxygen species (ROS) accumulation in leukemia cells and induces the expression of ROS generating enzymes (Q38971726)

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English	Decitabine induces delayed reactive oxygen species (ROS) accumulation in leukemia cells and induces the expression of ROS generating enzymes	scientific article

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scholarly article

1 reference

Europe PubMed Central

8 September 2017

Decitabine induces delayed reactive oxygen species (ROS) accumulation in leukemia cells and induces the expression of ROS generating enzymes (English)

1 reference

Europe PubMed Central

8 September 2017

reactive oxygen species

1 reference

based on heuristic

inferred from title

author name string

Tamer E Fandy

1

1 reference

Europe PubMed Central

8 September 2017

Anchalee Jiemjit

2

1 reference

Europe PubMed Central

8 September 2017

Manjusha Thakar

3

1 reference

Europe PubMed Central

8 September 2017

Paulette Rhoden

4

1 reference

Europe PubMed Central

8 September 2017

Lauren Suarez

5

1 reference

Europe PubMed Central

8 September 2017

Steven D Gore

6

1 reference

Europe PubMed Central

8 September 2017

language of work or name

0 references

publication date

14 January 2014

1 reference

Europe PubMed Central

8 September 2017

Clinical Cancer Research

1 reference

Europe PubMed Central

8 September 2017

20

1 reference

Europe PubMed Central

8 September 2017

5

1 reference

Europe PubMed Central

8 September 2017

1249-1258

1 reference

Europe PubMed Central

8 September 2017

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

1 reference

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Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.

1 reference

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Regulation of cell proliferation by NADPH oxidase-mediated signaling: potential roles in tissue repair, regenerative medicine and tissue engineering

1 reference

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NOX4 mediates hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: the role of autocrine production of transforming growth factor-{beta}1 and insulin-like growth factor binding protein-3.

1 reference

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9 September 2017

Nucleoside analogs: molecular mechanisms signaling cell death.

1 reference

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9 September 2017

Mechanisms of resistance to 5-aza-2'-deoxycytidine in human cancer cell lines

1 reference

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Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity

1 reference

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Redox regulation of cell survival

1 reference

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9 September 2017

Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia

1 reference

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9 September 2017

Mitochondrial membrane permeabilization in cell death

1 reference

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Mechanisms of cell death in oxidative stress

1 reference

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9 September 2017

Reactive oxygen species in cancer cells: live by the sword, die by the sword.

1 reference

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Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors

1 reference

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Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells

1 reference

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Hydrogen peroxide as second messenger in lymphocyte activation

1 reference

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Identification of renox, an NAD(P)H oxidase in kidney

1 reference

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NADPH oxidase: an update

1 reference

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Biological defense mechanisms. The effect of bacteria and serum on superoxide production by granulocytes

1 reference

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DNA methyltransferase 1 knockdown activates a replication stress checkpoint.

1 reference

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9 September 2017

Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000016

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p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage.

1 reference

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14 September 2017

DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

1 reference

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14 September 2017

Apoptosis by cisplatin requires p53 mediated p38alpha MAPK activation through ROS generation.

1 reference

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14 September 2017

Decitabine activates specific caspases downstream of p73 in myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000016

14 September 2017

5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia.

1 reference

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Oxidative stress attenuates Fas-mediated apoptosis in Jurkat T cell line through Bfl-1 induction.

1 reference

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14 September 2017

5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000016

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Induction of gene expression by 5-Aza-2'-deoxycytidine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) but not epithelial cells by DNA-methylation-dependent and -independent mechanisms

1 reference

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5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells

1 reference

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14 September 2017

5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation.

1 reference

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JNK1 activity lowers the cellular production of H2O2 and modulates the growth arrest response to scavenging of H2O2 by catalase

1 reference

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Potentiation of reactive oxygen species is a marker for synergistic cytotoxicity of MS-275 and 5-azacytidine in leukemic cells

1 reference

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17 June 2018

p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.

1 reference

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Comparison of the substrate specificities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs

1 reference

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17 June 2018

The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000016

21 August 2018

NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells

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21 August 2018

Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000016

21 August 2018

Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome

1 reference

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Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3'-azido-2',3'-dideoxythymidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24423613

12 December 2020

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Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/24423613

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inferred from PubMed ID database lookup

Nox 4 regulation of vascular smooth muscle cell differentiation marker gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24423613

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CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24423613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-13-1453

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

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