LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells (Q38976444)

8 September 2017

title

LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells (English)

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8 September 2017

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hepatocellular carcinoma

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H Xiong

1

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8 September 2017

Z Ni

2

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8 September 2017

J He

3

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8 September 2017

S Jiang

4

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8 September 2017

X Li

5

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8 September 2017

J He

6

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8 September 2017

W Gong

7

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8 September 2017

L Zheng

8

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8 September 2017

S Chen

9

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8 September 2017

B Li

10

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8 September 2017

N Zhang

11

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8 September 2017

X Lyu

12

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8 September 2017

G Huang

13

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8 September 2017

B Chen

14

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8 September 2017

Y Zhang

15

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8 September 2017

F He

16

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8 September 2017

language of work or name

English

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publication date

6 February 2017

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8 September 2017

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8 September 2017

volume

36

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8 September 2017

issue

25

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8 September 2017

page(s)

3528-3540

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Epidemiology of viral hepatitis and hepatocellular carcinoma

8 September 2017

cites work

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PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression

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Inhibition of p53 increases chemosensitivity to 5-FU in nutrient-deprived hepatocarcinoma cells by suppressing autophagy

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Long noncoding RNAs: cellular address codes in development and disease

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CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer

21 January 2018

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Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1).

21 January 2018

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Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18.

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Long noncoding RNA HULC modulates abnormal lipid metabolism in hepatoma cells through an miR-9-mediated RXRA signaling pathway

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Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth.

21 January 2018

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Ubiquitinated sirtuin 1 (SIRT1) function is modulated during DNA damage-induced cell death and survival

21 January 2018

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USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development.

21 January 2018

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Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity

21 January 2018

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A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

21 January 2018

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Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

21 January 2018

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Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway

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Heparanase Enhances Tumor Growth and Chemoresistance by Promoting Autophagy

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Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy

21 January 2018

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SIRT1 is a regulator of autophagy: Implications in gastric cancer progression and treatment

21 January 2018

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MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT1 in hepatocellular carcinoma

21 January 2018

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SIRT1 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma and its expression predicts poor prognosis

21 January 2018

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The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression

21 January 2018

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USP22 regulates oncogenic signaling pathways to drive lethal cancer progression

21 January 2018

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High USP22 expression indicates poor prognosis in hepatocellular carcinoma.

21 January 2018

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SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells

21 January 2018

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A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex

21 January 2018

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A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets

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Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding

21 January 2018

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LXRα-mediated downregulation of FOXM1 suppresses the proliferation of hepatocellular carcinoma cells

21 January 2018

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MicroRNA-363-mediated downregulation of S1PR1 suppresses the proliferation of hepatocellular carcinoma cells.

21 January 2018

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Burkholderia pseudomallei survival in lung epithelial cells benefits from miRNA-mediated suppression of ATG10.

21 January 2018

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hTERT promotes the invasion of gastric cancer cells by enhancing FOXO3a ubiquitination and subsequent ITGB1 upregulation

21 January 2018

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CARL lncRNA inhibits anoxia-induced mitochondrial fission and apoptosis in cardiomyocytes by impairing miR-539-dependent PHB2 downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.521

LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28166203

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Long non-coding RNA HULC promotes tumor angiogenesis in liver cancer by up-regulating sphingosine kinase 1 (SPHK1)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28166203

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2016.521

1 reference

Dimensions Publication ID

8 September 2017

1083686801

0 references

1 reference