Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells (Q38982374)

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scientific article published in June 2014

Language	Label	Description	Also known as
English	Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells	scientific article published in June 2014

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scholarly article

1 reference

Europe PubMed Central

8 September 2017

Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells (English)

1 reference

Europe PubMed Central

8 September 2017

apoptotic process

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Douglas R. Green

object named as

Douglas R Green

8

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author name string

Wei Qian

1

1 reference

Europe PubMed Central

8 September 2017

Jingnan Wang

2

1 reference

Europe PubMed Central

8 September 2017

Vera Roginskaya

3

1 reference

Europe PubMed Central

8 September 2017

Lee A McDermott

4

1 reference

Europe PubMed Central

8 September 2017

Robert P Edwards

5

1 reference

Europe PubMed Central

8 September 2017

Donna B Stolz

6

1 reference

Europe PubMed Central

8 September 2017

Fabien Llambi

7

1 reference

Europe PubMed Central

8 September 2017

Bennett Van Houten

9

1 reference

Europe PubMed Central

8 September 2017

language of work or name

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publication date

1 June 2014

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

5

1 reference

Europe PubMed Central

8 September 2017

4180-4194

1 reference

Europe PubMed Central

8 September 2017

12

1 reference

Europe PubMed Central

8 September 2017

Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

NOXA-induced alterations in the Bax/Smac axis enhance sensitivity of ovarian cancer cells to cisplatin

1 reference

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Minireview: human ovarian cancer: biology, current management, and paths to personalizing therapy

1 reference

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9 September 2017

Minireview: animal models and mechanisms of ovarian cancer development

1 reference

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9 September 2017

Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Molecular mechanisms of cisplatin resistance

1 reference

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9 September 2017

Role of Drp1, a key mitochondrial fission protein, in neuropathic pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

A selective inhibitor of drp1, mdivi-1, increases retinal ganglion cell survival in acute ischemic mouse retina

1 reference

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9 September 2017

Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine

1 reference

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9 September 2017

Alterations in bioenergetics due to changes in mitochondrial DNA copy number

1 reference

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9 September 2017

Drug combination studies and their synergy quantification using the Chou-Talalay method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Noxa: at the tip of the balance between life and death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Primary culture of ovarian surface epithelial cells and ascites-derived ovarian cancer cells from patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Mitochondrial membrane permeabilization in cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Cellular processing of platinum anticancer drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Transcription-coupled nucleotide excision repair as a determinant of cisplatin sensitivity of human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Advances in the screening and treatment of ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Cisplatin hypersensitivity of testicular germ cell tumors is determined by high constitutive Noxa levels mediated by Oct-4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

9 September 2017

Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

14 September 2017

Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

14 September 2017

PKD2 mediates multi-drug resistance in breast cancer cells through modulation of P-glycoprotein expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

14 September 2017

The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes

1 reference

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14 September 2017

Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

25 September 2017

Influence of cis-diamminedichloroplatinum(II) on DNA synthesis and cell cycle progression in excision repair proficient and deficient Chinese hamster ovary cells.

1 reference

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25 September 2017

An ERK-dependent pathway to Noxa expression regulates apoptosis by platinum-based chemotherapeutic drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

21 August 2018

Intraperitoneal cisplatin and paclitaxel in ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

21 August 2018

Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

21 August 2018

Abrogation of mitochondrial cytochrome c release and caspase-3 activation in acquired multidrug resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

21 August 2018

Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4147315

21 August 2018

A prospective study evaluating the clinical relevance of a chemoresponse assay for treatment of patients with persistent or recurrent ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24952704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct diffusion of cis-diamminedichloroplatinum(II) in intraperitoneal rat tumors after intraperitoneal chemotherapy: a comparison with systemic chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24952704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.1944

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1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

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