CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in mice (Q39003107)

8 September 2017

CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in mice (English)

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Per-Olof Berggren

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Pann-Ghill Suh

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Kyungmoo Yea

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Jaeyoon Kim

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Jaewang Ghim

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Parkyong Song

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Areum Lee

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Dayea Kim

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Yonghoon Kwon

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Jong Hyuk Yoon

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Soyeon Park

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Chun-Pyo Hong

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Min Seong Jang

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Sehoon Park

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Myoung Ho Jang

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18 April 2014

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1456-1465

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https://scigraph.springernature.com/pub.10.1007/s00125-014-3237-5

8 September 2017

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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Obesity is associated with macrophage accumulation in adipose tissue

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Mechanisms of inflammatory responses in obese adipose tissue

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The cellular and signaling networks linking the immune system and metabolism in disease

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JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

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JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation

21 January 2018

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Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals

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Macrophage-mediated inflammation in metabolic disease

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MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

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CCR2 modulates inflammatory and metabolic effects of high-fat feeding

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Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.

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Monocyte chemoattractant protein deficiency fails to restrain macrophage infiltration into adipose tissue [corrected].

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Bone marrow as a source of circulating CXCR4+ tissue-committed stem cells

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

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Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100

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Macrophages, inflammation, and insulin resistance

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CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

21 January 2018

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Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system

21 January 2018

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Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

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Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4.

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Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12.

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Chemokines in vascular dysfunction and remodeling.

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MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment

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MIF deficiency does not alter glucose homeostasis or adipose tissue inflammatory cell infiltrates during diet-induced obesity

21 January 2018

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The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes

21 January 2018

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The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer

21 January 2018

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CXCR7 protein is not expressed on human or mouse leukocytes

21 January 2018

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A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

21 January 2018

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Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands

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Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

21 January 2018

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Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes

21 January 2018

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Monocyte chemoattractant protein 1 in obesity and insulin resistance

21 January 2018

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Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance

21 January 2018

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Synergy between coproduced CC and CXC chemokines in monocyte chemotaxis through receptor-mediated events.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-014-3237-5

Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity

21 January 2018

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Recombinant IFN-alpha (2b) increases the expression of apoptosis receptor CD95 and chemokine receptors CCR1 and CCR3 in monocytoid cells

21 January 2018

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12 December 2020

Clinical analysis of systemic and adipose tissue levels of selected hormones/adipokines and stromal-derived factor-1

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12 December 2020

Interferon-gamma increases expression of chemokine receptors CCR1, CCR3, and CCR5, but not CXCR4 in monocytoid U937 cells

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12 December 2020

SDF-1 (CXCL12) is upregulated in the ischemic penumbra following stroke: association with bone marrow cell homing to injury

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12 December 2020

Hypoxia-induced production of stromal cell-derived factor 1 (CXCL12) and vascular endothelial growth factor by synovial fibroblasts

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12 December 2020

10.1007/S00125-014-3237-5

Identifiers

DOI

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8 September 2017

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