Small molecule-facilitated degradation of ANO1 protein: a new targeting approach for anticancer therapeutics. (Q39018217)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24599954%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Small molecule-facilitated degradation of ANO1 protein: a new targeting approach for anticancer therapeutics (English)

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9 March 2020

12

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9 March 2020

author name string

Anke Bill

1

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9 March 2020

Michelle Lynn Hall

2

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9 March 2020

Jason Borawski

3

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9 March 2020

Catherine Hodgson

4

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9 March 2020

Jeremy Jenkins

5

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9 March 2020

Philippe Piechon

6

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9 March 2020

Oana Popa

7

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9 March 2020

Christopher Rothwell

8

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9 March 2020

Pamela Tranter

9

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9 March 2020

Scott Tria

10

1 reference

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9 March 2020

Trixie Wagner

11

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9 March 2020

L Alex Gaither

13

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9 March 2020

language of work or name

English

0 references

publication date

5 March 2014

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Journal of Biological Chemistry

9 March 2020

number of pages

13

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based on heuristic

inferred from page(s)

published in

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9 March 2020

volume

289

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9 March 2020

issue

16

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9 March 2020

page(s)

11029-11041

1 reference

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Consistent and differential genetic aberrations between esophageal dysplasia and squamous cell carcinoma detected by array comparative genomic hybridization

9 March 2020

cites work

1 reference

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Activation of the Cl- channel ANO1 by localized calcium signals in nociceptive sensory neurons requires coupling with the IP3 receptor

9 September 2017

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Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC)

9 September 2017

1 reference

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Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling

9 September 2017

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The transmembrane protein 16A Ca(2+)-activated Cl- channel in airway smooth muscle contributes to airway hyperresponsiveness

9 September 2017

1 reference

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Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction

9 September 2017

1 reference

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Control of TMEM16A by INO-4995 and other inositolphosphates

9 September 2017

1 reference

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Anoctamins are a family of Ca2+-activated Cl- channels

9 September 2017

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Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network

9 September 2017

1 reference

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The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons

9 September 2017

1 reference

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International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels.

9 September 2017

1 reference

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Protein quality control in the ER: balancing the ubiquitin checkbook

9 September 2017

1 reference

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Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins.

9 September 2017

1 reference

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TMEM16A Inhibitors Reveal TMEM16A as a Minor Component of Calcium-activated Chloride Channel Conductance in Airway and Intestinal Epithelial Cells

9 September 2017

1 reference

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Characterization of the Oligomeric Structure of the Ca2+-activated Cl− Channel Ano1/TMEM16A

9 September 2017

1 reference

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TMEM16A(a)/anoctamin-1 Shares a Homodimeric Architecture with CLC Chloride Channels

9 September 2017

1 reference

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Cytohesins are cytoplasmic ErbB receptor activators

9 September 2017

1 reference

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Inhibition of Ca2+-activated Cl- channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea.

9 September 2017

1 reference

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Analysis and comparison of 2D fingerprints: insights into database screening performance using eight fingerprint methods

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036244

Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose.

9 September 2017

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QPatch: the missing link between HTS and ion channel drug discovery.

9 September 2017

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FieldScreen: virtual screening using molecular fields. Application to the DUD data set.

9 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036244

Genomewide mRNA profiling of esophageal squamous cell carcinoma for identification of cancer biomarkers.

9 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036244

Expression cloning of TMEM16A as a calcium-activated chloride channel subunit

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036244

TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036244

TMEM16A confers receptor-activated calcium-dependent chloride conductance

9 September 2017

1 reference

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The transmembrane protein TMEM16A is required for normal development of the murine trachea

9 September 2017

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Ubiquitylation of ion channels

9 September 2017

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Oncogene addiction: sometimes a temporary slavery

9 September 2017

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The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status

9 September 2017

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High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells.

9 September 2017

1 reference

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Degradation of CFTR by the ubiquitin-proteasome pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036244

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin A suggests an ER recycling pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036244

Inhibition of cell proliferation by a selective inhibitor of the Ca(2+)-activated Cl(-) channel, Ano1.

9 September 2017

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Novel 5-substituted benzyloxy-2-arylbenzofuran-3-carboxylic acids as calcium activated chloride channel inhibitors

9 September 2017

1 reference

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TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036244

The hydrophobic effect in protein folding

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036244

Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036244

Molecular field extrema as descriptors of biological activity: definition and validation.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036244

Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display.

21 August 2018

1 reference

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UA62784, a novel inhibitor of centromere protein E kinesin-like protein

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.549188

Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.549188

Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24599954

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Large-scale systematic analysis of 2D fingerprint methods and parameters to improve virtual screening enrichments

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24599954

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.549188

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24599954%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

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9 March 2020

PubMed publication ID

24599954

1 reference

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