Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma. (Q39042485)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24346431%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24346431%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

1 reference

1 reference

Kristina Y Aguilera

1

1 reference

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3 March 2020

Lee B Rivera

2

1 reference

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3 March 2020

Juliet G Carbon

4

1 reference

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3 March 2020

Jason E Toombs

5

1 reference

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3 March 2020

Courtney D Goldstein

6

1 reference

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3 March 2020

Diego H Castrillon

8

1 reference

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3 March 2020

Rolf A Brekken

9

1 reference

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3 March 2020

language of work or name

English

0 references

publication date

17 December 2013

1 reference

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3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24346431%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

74

1 reference

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3 March 2020

issue

4

1 reference

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3 March 2020

page(s)

1032-1044

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24346431%20AND%20SRC:MED&resulttype=core&format=json

Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer

3 March 2020

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9 September 2017

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9 September 2017

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9 September 2017

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Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activation

9 September 2017

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9 September 2017

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9 September 2017

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Anti-VEGF treatment-resistant pancreatic cancers secrete proinflammatory factors that contribute to malignant progression by inducing an EMT cell phenotype.

9 September 2017

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SPARC regulates collagen interaction with cardiac fibroblast cell surfaces

9 September 2017

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9 September 2017

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Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma

9 September 2017

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PEAK1, a novel kinase target in the fight against cancer

9 September 2017

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r84, a novel therapeutic antibody against mouse and human VEGF with potent anti-tumor activity and limited toxicity induction

9 September 2017

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Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303).

9 September 2017

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Methylation of the SPARC gene promoter and its clinical implication in pancreatic cancer

9 September 2017

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Smac mimetic increases chemotherapy response and improves survival in mice with pancreatic cancer

9 September 2017

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Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma

9 September 2017

1 reference

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Crystallographic insight into collagen recognition by discoidin domain receptor 2

9 September 2017

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SPARC: a matricellular regulator of tumorigenesis

9 September 2017

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

9 September 2017

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Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

9 September 2017

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Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

9 September 2017

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Structural basis of sequence-specific collagen recognition by SPARC

9 September 2017

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Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1

9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

9 September 2017

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9 September 2017

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The discoidin domain receptor tyrosine kinases are activated by collagen

9 September 2017

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Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

9 September 2017

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Tumor angiogenesis: therapeutic implications

9 September 2017

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Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

9 September 2017

1 reference

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PG545, an angiogenesis and heparanase inhibitor, reduces primary tumor growth and metastasis in experimental pancreatic cancer.

9 September 2017

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9 September 2017

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Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway

9 September 2017

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Native type IV collagen induces cell migration through a CD9 and DDR1-dependent pathway in MDA-MB-231 breast cancer cells

9 September 2017

1 reference

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An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies

14 September 2017

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14 September 2017

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Transforming growth factor-beta induces collagen synthesis without inducing IL-8 production in mesothelial cells.

14 September 2017

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TGF-β and αvβ6 integrin act in a common pathway to suppress pancreatic cancer progression

14 September 2017

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Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer

17 June 2018

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Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice.

21 August 2018

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SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength

21 August 2018

1 reference

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SPARC deficiency leads to early-onset cataractogenesis.

21 August 2018

1 reference

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Monoclonal antibodies recognizing transforming growth factor-beta. Bioactivity neutralization and transforming growth factor beta 2 affinity purification

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24346431

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24346431

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-13-2800

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24346431%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24346431%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference