BET bromodomain inhibition of MYC-amplified medulloblastoma. (Q39050679)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297863%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

BET bromodomain inhibition of MYC-amplified medulloblastoma (English)

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2 March 2020

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20

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2 March 2020

Fredrik J Swartling

21

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2 March 2020

Mark W. Kieran

22

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2 March 2020

24

Rameen Beroukhim

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2 March 2020

Pratiti Bandopadhayay

1

object named as

Pratiti Bandopadhayay

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2 March 2020

Robert J Wechsler-Reya

19

object named as

Robert Wechsler-Reya

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2 March 2020

author name string

Guillaume Bergthold

2

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2 March 2020

Brian Nguyen

3

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2 March 2020

Simone Schubert

4

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2 March 2020

Sharareh Gholamin

5

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2 March 2020

Yujie Tang

6

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2 March 2020

Sara Bolin

7

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2 March 2020

Steven E Schumacher

8

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2 March 2020

Rhamy Zeid

9

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2 March 2020

Sabran Masoud

10

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2 March 2020

Furong Yu

11

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2 March 2020

Nujsaubnusi Vue

12

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2 March 2020

William J Gibson

13

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2 March 2020

Brenton R Paolella

14

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2 March 2020

Siddhartha S Mitra

15

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2 March 2020

Samuel H Cheshier

16

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2 March 2020

Jun Qi

17

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2 March 2020

Kun-Wei Liu

18

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2 March 2020

James E Bradner

23

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2 March 2020

Yoon-Jae Cho

25

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2 March 2020

language of work or name

English

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publication date

2 December 2013

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2 March 2020

published in

Clinical Cancer Research

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2 March 2020

volume

20

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2 March 2020

issue

4

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2 March 2020

page(s)

912-925

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The role of chromatin remodeling in medulloblastoma.

2 March 2020

cites work

1 reference

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Targeting MYCN in neuroblastoma by BET bromodomain inhibition

9 September 2017

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Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers

9 September 2017

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Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML.

9 September 2017

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Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.

9 September 2017

1 reference

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Survival and secondary tumors in children with medulloblastoma receiving radiotherapy and adjuvant chemotherapy: results of Children's Oncology Group trial A9961.

9 September 2017

1 reference

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Subgroup-specific structural variation across 1,000 medulloblastoma genomes

9 September 2017

1 reference

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The bromodomain interaction module

9 September 2017

1 reference

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K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

9 September 2017

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Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.

9 September 2017

1 reference

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Absolute quantification of somatic DNA alterations in human cancer

9 September 2017

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Histone recognition and large-scale structural analysis of the human bromodomain family

9 September 2017

1 reference

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Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

9 September 2017

1 reference

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An animal model of MYC-driven medulloblastoma

9 September 2017

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Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

9 September 2017

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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

9 September 2017

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Molecular subgroups of medulloblastoma: the current consensus

9 September 2017

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Mutual exclusivity analysis identifies oncogenic network modules

9 September 2017

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BET bromodomain inhibition as a therapeutic strategy to target c-Myc

9 September 2017

1 reference

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Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

9 September 2017

1 reference

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Medulloblastoma comprises four distinct molecular variants

9 September 2017

1 reference

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9 September 2017

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9 September 2017

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The landscape of somatic copy-number alteration across human cancers

9 September 2017

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Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs

9 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198154

Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

9 September 2017

1 reference

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A faster circular binary segmentation algorithm for the analysis of array CGH data

9 September 2017

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

9 September 2017

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9 September 2017

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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

9 September 2017

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Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors

9 September 2017

1 reference

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A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

9 September 2017

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Comprehensive molecular cytogenetic investigation of chromosomal abnormalities in human medulloblastoma cell lines and xenograft

9 September 2017

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9 September 2017

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Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

9 September 2017

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Noncanonical regulation of the Hedgehog mediator GLI1 by c-MYC in Burkitt lymphoma

9 September 2017

1 reference

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Pleiotropic effects of miR-183~96~182 converge to regulate cell survival, proliferation and migration in medulloblastoma

9 September 2017

1 reference

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Sequential activation of Snail1 and N-Myc modulates sonic hedgehog-induced transformation of neural cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198154

Pleiotropic role for MYCN in medulloblastoma.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198154

Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198154

Algorithms for detecting significantly mutated pathways in cancer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198154

Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198154

Comparative gene marker selection suite.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198154

Neurocognitive consequences of risk-adapted therapy for childhood medulloblastoma.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198154

Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198154

Establishment and characterization of the human medulloblastoma cell line and transplantable xenograft D283 Med.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4198154

10.1158/1078-0432.CCR-13-2281

21 August 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297863%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

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2 March 2020

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