3,4-dihydroxybenzalacetone protects against Parkinson's disease-related neurotoxin 6-OHDA through Akt/Nrf2/glutathione pathway (Q39107984)

9 September 2017

title

3,4-dihydroxybenzalacetone protects against Parkinson's disease-related neurotoxin 6-OHDA through Akt/Nrf2/glutathione pathway (English)

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9 September 2017

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ChEBI release 2020-05-28

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Kei Gunjima

1

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9 September 2017

Ryoichi Tomiyama

2

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9 September 2017

Ken Takakura

3

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9 September 2017

Takashi Yamada

4

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9 September 2017

Koji Hashida

5

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9 September 2017

Yutaka Nakamura

6

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9 September 2017

Tetsuya Konishi

7

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9 September 2017

Seiichi Matsugo

8

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9 September 2017

Osamu Hori

9

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9 September 2017

publication date

1 January 2014

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Journal of Cellular Biochemistry

9 September 2017

published in

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9 September 2017

volume

115

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9 September 2017

issue

1

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9 September 2017

page(s)

151-160

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N-acetylcysteine and neurodegenerative diseases: basic and clinical pharmacology

9 September 2017

cites work

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Acute depletion of reduced glutathione causes extensive carbonylation of rat brain proteins

21 January 2018

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Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

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Parkinson's disease: mechanisms and models

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6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta

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Anti-cancer effect and structural characterization of endo-polysaccharide from cultivated mycelia of Inonotus obliquus

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Ethanol extract of Inonotus obliquus inhibits lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells.

21 January 2018

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Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents

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Glutathione depletion and oxidative stress

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Cancer cell cytotoxicity of extracts and small phenolic compounds from Chaga [Inonotus obliquus (persoon) Pilat].

21 January 2018

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Prevention of hydrogen peroxide-induced oxidative stress in PC12 cells by 3,4-dihydroxybenzalacetone isolated from Chaga (Inonotus obliquus (persoon) Pilat).

21 January 2018

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Biological effects of pramipexole on dopaminergic neuron-associated genes: relevance to neuroprotection.

21 January 2018

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Chaga mushroom extract inhibits oxidative DNA damage in human lymphocytes as assessed by comet assay.

21 January 2018

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In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus

21 January 2018

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Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients

21 January 2018

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Modulation of Nrf2/ARE pathway by food polyphenols: a nutritional neuroprotective strategy for cognitive and neurodegenerative disorders

21 January 2018

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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

21 January 2018

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Identification of a novel blocker of IkappaBalpha kinase activation that enhances apoptosis and inhibits proliferation and invasion by suppressing nuclear factor-kappaB.

21 January 2018

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A dibenzoylmethane derivative protects dopaminergic neurons against both oxidative stress and endoplasmic reticulum stress

21 January 2018

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Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2.

21 January 2018

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Cytotoxic constituents of propolis inducing anticancer effects: a review

21 January 2018

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Antioxidant Small Phenolic Ingredients in Inonotus obliquus (persoon) Pilat (Chaga)

21 January 2018

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/CPB.55.1222

Identifiers

DOI

10.1002/JCB.24643

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9 September 2017

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