6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta (Q40339108)

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scientific article published on 16 December 2005

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English	6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta	scientific article published on 16 December 2005

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

apoptotic process

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based on heuristic

inferred from title

author name string

Katharine Hanrott

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Louise Gudmunsen

2

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Europe PubMed Central

PubMed publication ID

19 September 2017

Michael J O'Neill

3

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Susan Wonnacott

4

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Europe PubMed Central

PubMed publication ID

19 September 2017

language of work or name

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publication date

16 December 2005

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Europe PubMed Central

PubMed publication ID

19 September 2017

number of pages

10

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inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

19 September 2017

281

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Europe PubMed Central

PubMed publication ID

19 September 2017

9

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Europe PubMed Central

PubMed publication ID

19 September 2017

5373-5382

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Europe PubMed Central

PubMed publication ID

19 September 2017

Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

6-Hydroxydopamine increases ubiquitin-conjugates and protein degradation: implications for the pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Bcl-x L blocks mitochondrial multiple conductance channel activation and inhibits 6-OHDA-induced death in SH-SY5Y cells

1 reference

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21 January 2018

Effects of 6-hydroxydopamine on primary cultures of substantia nigra: specific damage to dopamine neurons and the impact of glial cell line-derived neurotrophic factor

1 reference

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21 January 2018

Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine-induced neuronal death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

6-hydroxydopamine-induced nuclear factor-kappa B activation in PC12 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Induced expression of early response genes/oxidative injury in rat pheochromocytoma (PC12) cell line by 6-hydroxydopamine: implication for Parkinson's disease

1 reference

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21 January 2018

Autoradiographic demonstration of uptake and accumulation of3H-6-hydroxydopamine in adrenergic nerves

1 reference

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21 January 2018

Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

1 reference

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21 January 2018

Extracellular toxicity of 6-hydroxydopamine on PC12 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

The toxicity of 6-hydroxydopamine on PC12 and P19 cells

1 reference

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21 January 2018

Caspase-3-like proteases and 6-hydroxydopamine induced neuronal cell death

1 reference

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21 January 2018

JNK2 translocates to the mitochondria and mediates cytochrome c release in PC12 cells in response to 6-hydroxydopamine

1 reference

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21 January 2018

6-Hydroxydopamine induces dopaminergic cell degeneration via a caspase-9-mediated apoptotic pathway that is attenuated by caspase-9dn expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Regulation of cell apoptosis by protein kinase c delta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

The proteolytic cleavage of protein kinase C isotypes, which generates kinase and regulatory fragments, correlates with Fas-mediated and 12-O-tetradecanoyl-phorbol-13-acetate-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cdelta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Nuclear import of PKCdelta is required for apoptosis: identification of a novel nuclear import sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide

1 reference

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21 January 2018

Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Caspase‐3 dependent proteolytic activation of protein kinase Cδ mediates and regulates 1‐methyl‐4‐phenylpyridinium (MPP+)‐induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration

1 reference

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21 January 2018

Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration

1 reference

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21 January 2018

Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Toxic effects of MPP(+) and MPTP in PC12 cells independent of reactive oxygen species formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Nonspecific effects of the selective kappa-opioid receptor agonist U-50,488H on dopamine uptake and release in PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Inhibition of T cell apoptosis by IFN-beta rapidly reverses nuclear translocation of protein kinase C-delta.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

PKC-δ is an apoptotic lamin kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

PKCdelta is required for mitochondrial-dependent apoptosis in salivary epithelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Cholecystokinin-stimulated protein kinase C-delta kinase activation, tyrosine phosphorylation, and translocation are mediated by Src tyrosine kinases in pancreatic acinar cells

1 reference

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21 January 2018

Regulation of cadmium-induced apoptosis by PKCdelta in U937 human promonocytic cells

1 reference

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21 January 2018

Cephaloridine induces translocation of protein kinase C delta into mitochondria and enhances mitochondrial generation of free radicals in the kidney cortex of rats causing renal dysfunction

1 reference

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21 January 2018

Rottlerin, a novel protein kinase inhibitor

1 reference

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21 January 2018

Dieldrin promotes proteolytic cleavage of poly(ADP-ribose) polymerase and apoptosis in dopaminergic cells: protective effect of mitochondrial anti-apoptotic protein Bcl-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.

1 reference

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21 January 2018

Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase Cdelta tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

The PKC delta inhibitor, rottlerin, induces apoptosis of haematopoietic cell lines through mitochondrial membrane depolarization and caspases' cascade

1 reference

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21 January 2018

Down-regulation of Bcl-2, activation of caspases, and involvement of reactive oxygen species in 6-hydroxydopamine-induced thymocyte apoptosis

1 reference

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21 January 2018

The role of oxidative stress, impaired glycolysis and mitochondrial respiratory redox failure in the cytotoxic effects of 6-hydroxydopamine in vitro

1 reference

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21 January 2018

p-Quinone mediates 6-hydroxydopamine-induced dopaminergic neuronal death and ferrous iron accelerates the conversion of p-quinone into melanin extracellularly.

1 reference

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21 January 2018

Systemic administration of N-acetylcysteine protects dopaminergic neurons against 6-hydroxydopamine-induced degeneration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

The cytotoxicity of dopamine may be an artefact of cell culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Acute effects of 6-hydroxydopamine on dopaminergic neurons of the rat substantia nigra pars compacta in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

p53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PC12 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Exacerbated vein graft arteriosclerosis in protein kinase Cdelta-null mice

1 reference

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21 January 2018

Opposing effects of protein kinase C delta and protein kinase B alpha on H(2)O(2)-induced apoptosis in CHO cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

UV-induced tyrosine phosphorylation of PKC delta and promotion of apoptosis in the HaCaT cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Role of Proteolytic Activation of Protein Kinase Cδ in Oxidative Stress-Induced Apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

Tissue-specific developmental regulation of protein kinase C isoforms.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511560200

21 January 2018

p73β Is Regulated by Protein Kinase Cδ Catalytic Fragment Generated in the Apoptotic Response to DNA Damage

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M511560200

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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