Loss of IGFBP7 expression and persistent AKT activation contribute to SMARCB1/Snf5-mediated tumorigenesis (Q39126217)

9 September 2017

Loss of IGFBP7 expression and persistent AKT activation contribute to SMARCB1/Snf5-mediated tumorigenesis (English)

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9 September 2017

J Darr

1

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9 September 2017

A Klochendler

series ordinal

2

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9 September 2017

S Isaac

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3

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9 September 2017

A Eden

series ordinal

4

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9 September 2017

language of work or name

English

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publication date

15 July 2013

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9 September 2017

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9 September 2017

33

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9 September 2017

3024-3032

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9 September 2017

23

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https://scigraph.springernature.com/pub.10.1038/onc.2013.261

9 September 2017

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cites work

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression

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Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

21 January 2018

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SWI/SNF nucleosome remodellers and cancer.

21 January 2018

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Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

The tumor suppressor hSNF5/INI1 modulates cell growth and actin cytoskeleton organization

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Increased DNA damage sensitivity and apoptosis in cells lacking the Snf5/Ini1 subunit of the SWI/SNF chromatin remodeling complex

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Expression of SMARCB1 (INI1) mutations in familial schwannomatosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

INI1 expression induces cell cycle arrest and markers of senescence in malignant rhabdoid tumor cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

P-Akt expression distinguishes two types of malignant rhabdoid tumors

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Dependence on PI3K/Akt signaling for malignant rhabdoid tumor cell survival

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

The protein kinase B/Akt signalling pathway in human malignancy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Cellular survival: a play in three Akts

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Oncogenic kinase signalling

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

The BRG1- and hBRM-associated factor BAF57 induces apoptosis by stimulating expression of the cylindromatosis tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Role for BRG1 in cell cycle control and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Oncogenesis caused by loss of the SNF5 tumor suppressor is dependent on activity of BRG1, the ATPase of the SWI/SNF chromatin remodeling complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Endocytosis of membrane receptors: two pathways are better than one.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.261

Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7. Recombinant human mac25 protein specifically binds IGF-I and -II

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Recombinant insulin-like growth factor binding protein-1 inhibits IGF-I, serum, and estrogen-dependent growth of MCF-7 human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Insulin-like growth factor binding protein 7 exhibits tumor suppressive and vessel stabilization properties in U87MG and T98G glioblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Insulin-like growth factor-binding protein-7 functions as a potential tumor suppressor in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Insulin-like growth factor binding protein-7 (IGFBP7) blocks vascular endothelial cell growth factor (VEGF)-induced angiogenesis in human vascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Promoter chromatin remodeling of immediate-early genes is mediated through H3 phosphorylation at either serine 28 or 10 by the MSK1 multi-protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

A novel role of Brg1 in the regulation of SRF/MRTFA-dependent smooth muscle-specific gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Apoptotic response of malignant rhabdoid tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Novel role for insulin as an autocrine growth factor for malignant brain tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

IGFBP7: an oncosuppressor gene in thyroid carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Strong suppression of tumor growth by insulin-like growth factor-binding protein-related protein 1/tumor-derived cell adhesion factor/mac25.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

IGFBP7 reduces breast tumor growth by induction of senescence and apoptosis pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Essential roles of IGFBP-3 and IGFBP-rP1 in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Inhibition of insulin receptor activation by insulin-like growth factor binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Proteolytic processing of IGFBP-related protein-1 (TAF/angiomodulin/mac25) modulates its biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

IGFBP-3 and IGFBP-5 associate with the cell binding domain (CBD) of fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

The role of the insulin-like growth factor binding proteins and the IGFBP proteases in modulating IGF action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

INI1-deficient tumors: diagnostic features and molecular genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Tumor measurement in the nude mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

A human protein with homology to Saccharomyces cerevisiae SNF5 interacts with the potential helicase hbrm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Synergism between DNA methylation and macroH2A1 occupancy in epigenetic silencing of the tumor suppressor gene p16(CDKN2A).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

Chromatin remodeling factor encoded by ini1 induces G1 arrest and apoptosis in ini1-deficient cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.261

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.261

1 reference

9 September 2017

1 reference