IGFBP7 reduces breast tumor growth by induction of senescence and apoptosis pathways (Q39458425)

12 September 2017

title

IGFBP7 reduces breast tumor growth by induction of senescence and apoptosis pathways (English)

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12 September 2017

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Tania Benatar

1

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12 September 2017

Wenyi Yang

2

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12 September 2017

Yutaka Amemiya

3

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12 September 2017

Valentina Evdokimova

4

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12 September 2017

Harriette Kahn

5

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12 September 2017

Claire Holloway

6

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12 September 2017

Arun Seth

7

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12 September 2017

language of work or name

English

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publication date

14 October 2011

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Breast Cancer Research and Treatment

12 September 2017

published in

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12 September 2017

volume

133

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12 September 2017

issue

2

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12 September 2017

page(s)

563-573

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Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

12 September 2017

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Downregulation of the potential suppressor gene IGFBP-rP1 in human breast cancer is associated with inactivation of the retinoblastoma protein, cyclin E overexpression and increased proliferation in estrogen receptor negative tumors

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Down-regulation of T1A12/mac25, a novel insulin-like growth factor binding protein related gene, is associated with disease progression in breast carcinomas

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Insulin like growth factor binding protein-7 reduces growth of human breast cancer cells and xenografted tumors

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p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms

21 January 2018

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In-vivo transfection of pcDNA3.1-IGFBP7 inhibits melanoma growth in mice through apoptosis induction and VEGF downexpression

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Insulin-like growth factor binding protein-related protein 1 mediates VEGF-induced proliferation, migration and tube formation of retinal endothelial cells

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Insulin-like growth factor binding protein-7 (IGFBP7) blocks vascular endothelial cell growth factor (VEGF)-induced angiogenesis in human vascular endothelial cells.

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Reactivation of IGFBP7 by DNA demethylation inhibits human colon cancer cell growth in vitro

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Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase

21 January 2018

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Influence of induced reactive oxygen species in p53-mediated cell fate decisions.

21 January 2018

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A model for p53-induced apoptosis

21 January 2018

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Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway

21 January 2018

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Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

21 January 2018

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The insulin-like growth factor-binding protein (IGFBP) superfamily

21 January 2018

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Over-expression of insulin-like growth factor binding protein-related protein-1(IGFBP-rP1/mac25) in the M12 prostate cancer cell line alters tumor growth by a delay in G1 and cyclin A associated apoptosis

21 January 2018

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Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer

21 January 2018

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Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression

21 January 2018

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21 January 2018

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Tumor suppressor gene insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) induces senescence-like growth arrest in colorectal cancer cells

21 January 2018

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Enhanced expression of an insulin growth factor-like binding protein (mac25) in senescent human mammary epithelial cells and induced expression with retinoic acid

21 January 2018

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Insulin-like growth factor binding protein 3 accumulates to high levels in culture medium of senescent and quiescent human fibroblasts.

21 January 2018

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Proteolytic processing of IGFBP-related protein-1 (TAF/angiomodulin/mac25) modulates its biological activity

21 January 2018

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Interaction of IGF-Binding Protein-Related Protein 1 with a Novel Protein, Neuroendocrine Differentiation Factor, Results in Neuroendocrine Differentiation of Prostate Cancer Cells

21 January 2018

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Insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 share a common nuclear transport pathway in T47D human breast carcinoma cells

21 January 2018

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Cellular internalization of insulin-like growth factor binding protein-3: distinct endocytic pathways facilitate re-uptake and nuclear localization

21 January 2018

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Nuclear insulin-like growth factor binding protein-3 induces apoptosis and is targeted to ubiquitin/proteasome-dependent proteolysis.

21 January 2018

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10.1007/S10549-011-1816-4

21 January 2018

Identifiers

DOI

1 reference

12 September 2017

1 reference