Desmoglein 3 promotes cancer cell migration and invasion by regulating activator protein 1 and protein kinase C-dependent-Ezrin activation. (Q39141633)

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2 March 2020

title

Desmoglein 3 promotes cancer cell migration and invasion by regulating activator protein 1 and protein kinase C-dependent-Ezrin activation (English)

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2 March 2020

10

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author name string

L Brown

1

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2 March 2020

A Waseem

2

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2 March 2020

I N Cruz

3

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2 March 2020

J Szary

4

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2 March 2020

E Gunic

5

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2 March 2020

T Mannan

6

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2 March 2020

M Unadkat

7

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2 March 2020

M Yang

8

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2 March 2020

F Valderrama

9

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2 March 2020

H Wan

11

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2 March 2020

language of work or name

English

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publication date

10 June 2013

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2 March 2020

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2 March 2020

volume

33

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issue

18

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page(s)

2363-2374

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Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

2 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Extracellular domain of pemphigus vulgaris antigen (desmoglein 3) mediates weak homophilic adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Desmoglein endocytosis and desmosome disassembly are coordinated responses to pemphigus autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

P120-catenin is a novel desmoglein 3 interacting partner: identification of the p120-catenin association site of desmoglein 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Non-junctional human desmoglein 3 acts as an upstream regulator of Src in E-cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Desmoglein 3 acting as an upstream regulator of Rho GTPases, Rac-1/Cdc42 in the regulation of actin organisation and dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Desmosomes: a role in cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Immunohistochemical study of desmosomes in oral squamous cell carcinoma: correlation with cytokeratin and E-cadherin staining, and with tumour behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

A molecular study of desmosomes identifies a desmoglein isoform switch in head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

The role of desmoglein-3 in the diagnosis of squamous cell carcinoma of the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

DSG3 as a biomarker for the ultrasensitive detection of occult lymph node metastasis in oral cancer using nanostructured immunoarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Molecular staging of cervical lymph nodes in squamous cell carcinoma of the head and neck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Pemphigus vulgaris antigen mRNA quantification for the staging of sentinel lymph nodes in head and neck cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Intraoperative qRT-PCR for detection of lymph node metastasis in head and neck cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Regulation of cortical structure by the ezrin-radixin-moesin protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Identification and functional analysis of the ezrin-binding site in the hyaluronan receptor, CD44.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

High turnover of ezrin T567 phosphorylation: conformation, activity, and cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Protein kinase C regulates ezrin-radixin-moesin phosphorylation in canine osteosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Actin microdomains on endothelial cells: association with CD44, ERM proteins, and signaling molecules during quiescence and wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

A novel PKC-regulated mechanism controls CD44 ezrin association and directional cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Atypical protein kinase C (iota) activates ezrin in the apical domain of intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Rho kinase phosphorylation promotes ezrin-mediated metastasis in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

A possible mechanism for ezrin to establish epithelial cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Ezrin, a key component in tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Ezrin promotes ovarian carcinoma cell invasion and its retained expression predicts poor prognosis in ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Expression of ezrin is associated with invasion and dedifferentiation of hepatitis B related hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Intense cytoplasmic ezrin immunoreactivity predicts poor survival in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Ezrin promotes invasion and metastasis of pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Expression of the membrane-cytoskeletal linker Ezrin in salivary gland adenoid cystic carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Knockdown of ezrin via RNA interference suppresses Helicobacter pylori-enhanced invasion of gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Roles of ezrin in the growth and invasiveness of esophageal squamous carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

RNAi-mediated silencing of ezrin gene reverses malignant behavior of human gastric cancer cell line SGC-7901.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Directed actin polymerization is the driving force for epithelial cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Development of a quantitative method to analyse tumour cell invasion in organotypic culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

The ARP2/3 complex: an actin nucleator comes of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

N,N'-dinitrosopiperazine-mediated ezrin protein phosphorylation via activation of Rho kinase and protein kinase C is involved in metastasis of nasopharyngeal carcinoma 6-10B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Organizing the cell cortex: the role of ERM proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Androgen induction of prostate cancer cell invasion is mediated by ezrin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Heterotypic and homotypic associations between ezrin and moesin, two putative membrane-cytoskeletal linking proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Protein kinase C alpha/beta inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Protein kinase C activation disrupts epithelial apical junctions via ROCK-II dependent stimulation of actomyosin contractility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Ezrin, radixin, and moesin are phosphorylated in response to 2-methoxyestradiol and modulate endothelial hyperpermeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

ROCK and Dia have opposing effects on adherens junctions downstream of Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Transcription factors control invasion: AP-1 the first among equals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Regulation of a multigenic invasion programme by the transcription factor, AP-1: re-expression of a down-regulated gene, TSC-36, inhibits invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Co-operative effect of c-Src and ezrin in deregulation of cell-cell contacts and scattering of mammary carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Initiation of malignancy by duodenal contents reflux and the role of ezrin in developing esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Outside-in signaling through integrins and cadherins: a central mechanism to control epidermal growth and differentiation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Desmosomes and disease: pemphigus and bullous impetigo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

A pathogenic autoantibody, pemphigus vulgaris-IgG, induces phosphorylation of desmoglein 3, and its dissociation from plakoglobin in cultured keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Actin reorganization contributes to loss of cell adhesion in pemphigus vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Amphetamine-induced ERM Proteins Phosphorylation Is through PKCβ Activation in PC12 Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Ezrin/radixin/moesin proteins are phosphorylated by TNF-alpha and modulate permeability increases in human pulmonary microvascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Ezrin regulates E-cadherin-dependent adherens junction assembly through Rac1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Psoriasin (S100A7) associates with integrin β6 subunit and is required for αvβ6-dependent carcinoma cell invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Pemphigus vulgaris antigen is a desmosomal desmoglein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Expression of Ezrin and phosphorylated Ezrin (pEzrin) in pancreatic ductal adenocarcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Desmosome signaling. Inhibition of p38MAPK prevents pemphigus vulgaris IgG-induced cytoskeleton reorganization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.186

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.186

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23752190%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference