Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases (Q39154743)

9 September 2017

Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases (English)

1 reference

9 September 2017

13

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7 June 2020

author name string

Kamil Paruch

1

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7 June 2020

Michael P Dwyer

2

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7 June 2020

Carmen Alvarez

3

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7 June 2020

Courtney Brown

4

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7 June 2020

Tin-Yau Chan

5

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7 June 2020

Ronald J Doll

6

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7 June 2020

Kerry Keertikar

7

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7 June 2020

Chad Knutson

8

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7 June 2020

Brian McKittrick

9

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7 June 2020

Jocelyn Rivera

10

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7 June 2020

Randall Rossman

11

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7 June 2020

Greg Tucker

12

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7 June 2020

Alan Hruza

14

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7 June 2020

Vincent Madison

15

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7 June 2020

Amin A Nomeir

16

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7 June 2020

Yaolin Wang

17

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7 June 2020

Paul Kirschmeier

18

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7 June 2020

Emma Lees

19

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7 June 2020

David Parry

20

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7 June 2020

Nicole Sgambellone

21

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7 June 2020

Wolfgang Seghezzi

22

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7 June 2020

Lesley Schultz

23

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7 June 2020

Frances Shanahan

24

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7 June 2020

Derek Wiswell

25

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7 June 2020

Xiaoying Xu

26

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7 June 2020

Quiao Zhou

27

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7 June 2020

Ray A James

28

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7 June 2020

Vidyadhar M Paradkar

29

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Haengsoon Park

30

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Laura R Rokosz

31

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Tara M Stauffer

32

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Timothy J Guzi

33

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7 June 2020

language of work or name

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17 May 2010

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ACS Medicinal Chemistry Letters

9 September 2017

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7 June 2020

volume

1

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issue

5

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7 June 2020

page(s)

204-208

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Dinaciclib (SCH 727965), a novel and potent cyclin-dependent kinase inhibitor.

7 June 2020

cites work

1 reference

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Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms.

10 September 2017

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10 September 2017

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E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8

10 September 2017

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Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design

10 September 2017

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10 September 2017

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10 September 2017

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Cyclin-dependent kinase 5 (Cdk5): a potential therapeutic target for the treatment of neurodegenerative diseases and diabetes mellitus

10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

Recycling the Cell Cycle

1 reference

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Regulation of RNA polymerase II activity by CTD phosphorylation and cell cycle control

10 September 2017

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S and G2 phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells

10 September 2017

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10 September 2017

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Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

10 September 2017

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Distinct roles for cyclin-dependent kinases in cell cycle control

10 September 2017

1 reference

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Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

10 September 2017

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In vitro and in vivo activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials

10 September 2017

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Combined depletion of cell cycle and transcriptional cyclin-dependent kinase activities induces apoptosis in cancer cells

14 September 2017

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24900195

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ML100051D

1 reference

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7 June 2020

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7 June 2020

PubMed publication ID

24900195

1 reference