DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer (Q39166828)

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scientific article published on 15 April 2013

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English	DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer	scientific article published on 15 April 2013

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scholarly article

1 reference

Europe PubMed Central

9 September 2017

DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer (English)

1 reference

Europe PubMed Central

9 September 2017

1 reference

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author name string

D-W Wu

1

1 reference

Europe PubMed Central

9 September 2017

M-C Lee

2

1 reference

Europe PubMed Central

9 September 2017

J Wang

3

1 reference

Europe PubMed Central

9 September 2017

C-Y Chen

4

1 reference

Europe PubMed Central

9 September 2017

Y-W Cheng

5

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Europe PubMed Central

9 September 2017

H Lee

6

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Europe PubMed Central

9 September 2017

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publication date

15 April 2013

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Europe PubMed Central

9 September 2017

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Europe PubMed Central

9 September 2017

33

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Europe PubMed Central

9 September 2017

12

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Europe PubMed Central

9 September 2017

1515-1526

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Europe PubMed Central

9 September 2017

https://scigraph.springernature.com/pub.10.1038/onc.2013.107

0 references

Assessing TP53 status in human tumours to evaluate clinical outcome

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest

1 reference

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21 January 2018

The IARC TP53 database: new online mutation analysis and recommendations to users

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Mdm2 promotes the rapid degradation of p53

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https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

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Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

The role of the E6-p53 interaction in the molecular pathogenesis of HPV.

1 reference

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21 January 2018

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Stage-specific sensitivity to p53 restoration during lung cancer progression.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Selective activation of p53-mediated tumour suppression in high-grade tumours

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

The EMT regulator slug and lung carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Epithelial-mesenchymal transitions in tumour progression

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

The snail superfamily of zinc-finger transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

p53 and its mutants in tumor cell migration and invasion

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

DDX3, a DEAD box RNA helicase, is deregulated in hepatitis virus-associated hepatocellular carcinoma and is involved in cell growth control

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

DDX3, a DEAD box RNA helicase with tumor growth-suppressive property and transcriptional regulation activity of the p21waf1/cip1 promoter, is a candidate tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Phosphorylation of threonine 204 of DEAD-box RNA helicase DDX3 by cyclin B/cdc2 in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Oncogenic role of DDX3 in breast cancer biogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Reduced p21(WAF1/CIP1) via alteration of p53-DDX3 pathway is associated with poor relapse-free survival in early-stage human papillomavirus-associated lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

High-risk HPV/ErbB-2 interaction on E-cadherin/catenin regulation in human carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Epigenetic repression of E-cadherin by human papillomavirus 16 E7 protein

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Effects of HPV-16 E5, E6 and E7 proteins on survival, adhesion, migration and invasion of trophoblastic cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Depletion of Langerhans cells in human papillomavirus type 16-infected skin is associated with E6-mediated down regulation of E-cadherin

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Human papillomavirus type 16/18 up-regulates the expression of interleukin-6 and antiapoptotic Mcl-1 in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Human telomerase reverse transcriptase activated by E6 oncoprotein is required for human papillomavirus-16/18-infected lung tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

The E-cadherin cell-cell adhesion complex and lung cancer invasion, metastasis, and prognosis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Targets for transcriptional activation by wild-type p53: endogenous retroviral LTR, immunoglobulin-like promoter, and an internal promoter of the mdm2 gene

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Associations of MDM2 SNP309, transcriptional activity, mRNA expression, and survival in stage I non-small-cell lung cancer patients with wild-type p53 tumors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Twist and p53 reciprocally regulate target genes via direct interaction

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Lack of association between human papillomavirus type 16 and 18 infections and female lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Incidence of human papilloma virus in lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Gender difference in DNA adduct levels among nonsmoking lung cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Assessment of human papillomavirus in lung tumor tissue

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Papillomaviruses and cancer: from basic studies to clinical application

1 reference

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21 January 2018

Paxillin predicts survival and relapse in non-small cell lung cancer by microRNA-218 targeting

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

p53 dysfunction by xeroderma pigmentosum group C defects enhance lung adenocarcinoma metastasis via increased MMP1 expression

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

MDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Notch1 binds and induces degradation of Snail in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

In vitro and in vivo growth suppression of human papillomavirus 16-positive cervical cancer cells by e6 siRNA

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Slug enhances invasion ability of pancreatic cancer cells through upregulation of matrix metalloproteinase-9 and actin cytoskeleton remodeling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

21 January 2018

Expression of CD44v6 but not E-cadherin or beta-catenin influences prognosis in primary pulmonary adenocarcinoma

1 reference

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21 January 2018

The expression of beta-catenin in non-small-cell lung cancer: a clinicopathological study

1 reference

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Human papillomavirus 16/18 E6 oncoprotein is expressed in lung cancer and related with p53 inactivation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.107

31 March 2020

Expression status of E-cadherin and alpha-, beta-, and gamma-catenins in thymoma

1 reference

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31 March 2020

Prevalence of human papillomaviruses in lung carcinomas: a study of 218 cases.

1 reference

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Reciprocal down-regulation of p53 and SOD2 gene expression-implication in p53 mediated apoptosis

1 reference

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31 March 2020

Reduced E-cadherin expression is associated with increased lymph node metastasis and unfavorable prognosis in non-small cell lung cancer

1 reference

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31 March 2020

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10.1038/ONC.2013.107

1 reference

Europe PubMed Central

9 September 2017

1 reference

Europe PubMed Central

9 September 2017

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