MiR-139 inhibits Mcl-1 expression and potentiates TMZ-induced apoptosis in glioma. (Q39172188)

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27 February 2020

title

MiR-139 inhibits Mcl-1 expression and potentiates TMZ-induced apoptosis in glioma (English)

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27 February 2020

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Rui-Yan Li

1

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27 February 2020

Ling-Chao Chen

2

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Hai-Yan Zhang

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Wen-Zhong Du

4

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Yan Feng

5

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Han-Bing Wang

6

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Jin-Qiong Wen

7

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Xin Liu

8

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Xian-Feng Li

9

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Ying Sun

10

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Dong-Bo Yang

11

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27 February 2020

Tao Jiang

12

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27 February 2020

Yong-Li Li

13

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Chuan-Lu Jiang

14

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publication date

2 April 2013

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CNS Neuroscience & Therapeutics

27 February 2020

published in

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volume

19

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27 February 2020

issue

7

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27 February 2020

page(s)

477-483

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A brief review on the mechanisms of miRNA regulation

27 February 2020

cites work

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MicroRNA signatures in human cancers

21 January 2018

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miR-137 is frequently down-regulated in glioblastoma and is a negative regulator of Cox-2.

21 January 2018

1 reference

Targeting miR-21 in glioma: a small RNA with big potential

21 January 2018

1 reference

Co-delivery of as-miR-21 and 5-FU by poly(amidoamine) dendrimer attenuates human glioma cell growth in vitro

21 January 2018

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High level of miR-221/222 confers increased cell invasion and poor prognosis in glioma

21 January 2018

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An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

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VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1α/VEGF and β-catenin/Tcf-4 signaling

21 January 2018

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Upregulation of miR-196b confers a poor prognosis in glioblastoma patients via inducing a proliferative phenotype

21 January 2018

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Human glioma growth is controlled by microRNA-10b

21 January 2018

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miR-182 as a prognostic marker for glioma progression and patient survival.

21 January 2018

1 reference

Mcl-1 overexpression in hepatocellular carcinoma: a potential target for antisense therapy

21 January 2018

1 reference

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis

21 January 2018

1 reference

Mcl-1 is a relevant therapeutic target in acute and chronic lymphoid malignancies: down-regulation enhances rituximab-mediated apoptosis and complement-dependent cytotoxicity

21 January 2018

1 reference

Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma

21 January 2018

1 reference

ELK4 neutralization sensitizes glioblastoma to apoptosis through downregulation of the anti-apoptotic protein Mcl-1

21 January 2018

1 reference

Regulation of RAP1B by miR-139 suppresses human colorectal carcinoma cell proliferation

21 January 2018

1 reference

MiR-139 inhibits invasion and metastasis of colorectal cancer by targeting the type I insulin-like growth factor receptor

21 January 2018

1 reference

miR-139 impacts FoxO1 action by decreasing FoxO1 protein in mouse hepatocytes.

21 January 2018

1 reference

Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma

21 January 2018

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Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death

21 January 2018

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MicroRNA delivery by cationic lipoplexes for lung cancer therapy

21 January 2018

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MicroRNA 133B targets pro-survival molecules MCL-1 and BCL2L2 in lung cancer

21 January 2018

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MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity

21 January 2018

1 reference

MBP-1 upregulates miR-29b that represses Mcl-1, collagens, and matrix-metalloproteinase-2 in prostate cancer cells

21 January 2018

1 reference

Hepatitis C Virus Proteins Modulate MicroRNA Expression and Chemosensitivity in Malignant Hepatocytes

21 January 2018

1 reference

Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells.

21 January 2018

1 reference

[The mechanism of apoptosis in human U87 glioma cells induced by miR-21 antisense oligonucleotide].

21 January 2018

1 reference

12 December 2020

Co-suppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo

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12 December 2020

miR-221/222 promote malignant progression of glioma through activation of the Akt pathway.

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12 December 2020

AKT2 expression is associated with glioma malignant progression and required for cell survival and invasion.

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12 December 2020

Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3.

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12 December 2020

Downregulation of miR-221/222 sensitizes glioma cells to temozolomide by regulating apoptosis independently of p53 status.

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12 December 2020

[Influence of knock-down of miR-21 expression on the radiosensitivity of glioma SHG-44 cells].

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12 December 2020

Derepression of c-Fos caused by microRNA-139 down-regulation contributes to the metastasis of human hepatocellular carcinoma.

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12 December 2020

Identifiers

DOI

10.1111/CNS.12089

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27 February 2020

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27 February 2020

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