Targeting miR-21 in glioma: a small RNA with big potential (Q37799840)

23 August 2017

Targeting miR-21 in glioma: a small RNA with big potential (English)

1 reference

23 August 2017

Lynette M Moore

1

1 reference

PubMed ID

20942748

23 August 2017

Wei Zhang

series ordinal

2

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PubMed ID

20942748

23 August 2017

language of work or name

English

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publication date

1 November 2010

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Expert Opinion on Therapeutic Targets

23 August 2017

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23 August 2017

14

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23 August 2017

11

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23 August 2017

1247-1257

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The 2007 WHO classification of tumours of the central nervous system

23 August 2017

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https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Mechanisms of disease: genetic predictors of response to treatment in brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Imatinib mesylate in the treatment of gastrointestinal stromal tumour

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Genetic pathways to primary and secondary glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Malignant glioma: genetics and biology of a grave matter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Phase II trial of gefitinib in recurrent glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Bevacizumab and irinotecan in the treatment of recurrent malignant gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Mechanisms of gene silencing by double-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA expression profiles classify human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Extensive modulation of a set of microRNAs in primary glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

miR-21 and 221 upregulation and miR-181b downregulation in human grade II-IV astrocytic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Identification and functional characterization of microRNAs involved in the malignant progression of gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.527334

RNA polymerase III transcribes human microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Many roads to maturity: microRNA biogenesis pathways and their regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

SMAD proteins control DROSHA-mediated microRNA maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Foxo3a regulates apoptosis by negatively targeting miR-21

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Involvement of programmed cell death 4 in transforming growth factor-beta1-induced apoptosis in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Overexpression of miR-21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

BMPRII is a direct target of miR-21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Co-delivery of as-miR-21 and 5-FU by poly(amidoamine) dendrimer attenuates human glioma cell growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Downregulation of miR-21 enhances chemotherapeutic effect of taxol in breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

A direct comparison of anti-microRNA oligonucleotide potency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Improved targeting of miRNA with antisense oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

LNA-mediated microRNA silencing in non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Specificity, duplex degradation and subcellular localization of antagomirs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.527334

10.1517/14728222.2010.527334

21 January 2018

Identifiers

DOI

1 reference

23 August 2017

1 reference

PubMed ID

20942748