A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation (Q39180736)

9 September 2017

title

A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation (English)

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9 September 2017

10

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Zora Modrusan

8

object named as

Zora Modrusan

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9 September 2017

12

David Stokoe

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9 September 2017

Carolyn Bentley

1

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9 September 2017

Stefanie S Jurinka

2

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9 September 2017

Noelyn M Kljavin

3

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9 September 2017

Steffan Vartanian

4

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9 September 2017

Sree R Ramani

5

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9 September 2017

Lino C Gonzalez

6

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9 September 2017

Kebing Yu

7

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9 September 2017

Pan Du

9

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9 September 2017

Richard M Neve

11

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9 September 2017

language of work or name

English

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publication date

1 June 2013

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9 September 2017

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9 September 2017

volume

452

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9 September 2017

issue

2

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9 September 2017

page(s)

313-320

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Ras oncogenes: split personalities

9 September 2017

cites work

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https://api.crossref.org/works/10.1042%2FBJ20121578

Isoform-specific ras functions in development and cancer

21 January 2018

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Live-cell imaging of endogenous Ras-GTP illustrates predominant Ras activation at the plasma membrane

21 January 2018

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Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses

21 January 2018

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Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20121578

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20121578

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20121578

Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20121578

Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121578

Loss of the normal N-ras allele in a mouse thymic lymphoma induced by a chemical carcinogen

21 January 2018

1 reference

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Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20121578

Wildtype Kras2 can inhibit lung carcinogenesis in mice

21 January 2018

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Selective activation of p53-mediated tumour suppression in high-grade tumours

21 January 2018

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Inhibition of Ras oncogenic activity by Ras protooncogenes

21 January 2018

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Tumour maintenance is mediated by eNOS.

21 January 2018

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Genome Engineering With Zinc-Finger Nucleases

21 January 2018

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Zinc finger nucleases as tools to understand and treat human diseases

21 January 2018

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B-Raf is dispensable for K-Ras-mediated oncogenesis in human cancer cells

21 January 2018

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Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20121578

Comparative analysis of Erk phosphorylation suggests a mixed strategy for measuring phospho-form distributions

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20121578

Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines

21 January 2018

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The emerging mechanisms of isoform-specific PI3K signalling

21 January 2018

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

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Epidermal growth factor receptor: mechanisms of activation and signalling.

21 January 2018

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Interaction of a novel GDP exchange inhibitor with the Ras protein

21 January 2018

1 reference

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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121578

Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation

21 January 2018

1 reference

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The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121578

Oncogenic and wild-type Ras play divergent roles in the regulation of mitogen-activated protein kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121578

Sos-mediated cross-activation of wild-type Ras by oncogenic Ras is essential for tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121578

An unbiased genome-wide analysis of zinc-finger nuclease specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121578

A TALE nuclease architecture for efficient genome editing

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20121578

21 January 2018

Identifiers

DOI

10.1042/BJ20121578

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9 September 2017

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