Tumour maintenance is mediated by eNOS. (Q40001801)

16 September 2017

Tumour maintenance is mediated by eNOS. (English)

1 reference

16 September 2017

David F Kashatus

3

0 references

Kian-Huat Lim

object named as

Kian-Huat Lim

series ordinal

1

0 references

author name string

Brooke B Ancrile

series ordinal

2

1 reference

16 September 2017

Christopher M Counter

series ordinal

4

1 reference

16 September 2017

language of work or name

English

0 references

publication date

16 March 2008

1 reference

16 September 2017

1 reference

16 September 2017

452

1 reference

16 September 2017

7187

1 reference

16 September 2017

646-649

1 reference

https://scigraph.springernature.com/pub.10.1038/nature06778

16 September 2017

0 references

cites work

Oncogenic NRAS, KRAS, and HRAS exhibit different leukemogenic potentials in mice

1 reference

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Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis.

22 September 2017

1 reference

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Wild-type NRas and KRas perform distinct functions during transformation

22 September 2017

1 reference

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Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.

22 September 2017

1 reference

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The role of nitric oxide in tumour progression

22 September 2017

1 reference

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A genetically defined normal human somatic cell system to study ras oncogenesis in vivo and in vitro

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Loss of heterozygosity of Kras2 gene on 12p12-13 in Chinese colon carcinoma patients

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Activation of RalA is critical for Ras-induced tumorigenesis of human cells.

22 September 2017

1 reference

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Protein S-nitrosylation: purview and parameters

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Conditional animal models: a strategy to define when oncogenes will be effective targets to treat cancer.

22 September 2017

1 reference

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Targeting the PI3K-Akt pathway in human cancer: rationale and promise

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Targeting RAS signalling pathways in cancer therapy

22 September 2017

1 reference

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Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

22 September 2017

1 reference

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Cellular transformation by SV40 large T antigen: interaction with host proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Protein S-nitrosylation: a physiological signal for neuronal nitric oxide

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

The Akt kinase signals directly to endothelial nitric oxide synthase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Identification and characterization of an IkappaB kinase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Elevated blood pressures in mice lacking endothelial nitric oxide synthase.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Ha-ras and N-ras regulate MAPK activity by distinct mechanisms in vivo

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

LOH of chromosome 12p correlates with Kras2 mutation in non-small cell lung cancer

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Redox regulation of cell signalling

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Plasma membrane-targeted ras GTPase-activating protein is a potent suppressor of p21ras function

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688829

Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated K-ras genes

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18344980

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective inhibition of tumor microvascular permeability by cavtratin blocks tumor progression in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18344980

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE06778

1 reference

Dimensions Publication ID

16 September 2017

0 references

1 reference

16 September 2017

PubMed publication ID

18344980

1 reference