An ERBB3/ERBB2 oncogenic unit plays a key role in NRG1 signaling and melanoma cell growth and survival (Q39182371)

9 September 2017

title

An ERBB3/ERBB2 oncogenic unit plays a key role in NRG1 signaling and melanoma cell growth and survival (English)

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9 September 2017

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Keman Zhang

1

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9 September 2017

Poki Wong

2

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9 September 2017

Jiaqi Duan

3

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9 September 2017

Barbara Jacobs

4

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9 September 2017

Ernest C Borden

5

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9 September 2017

Barbara Bedogni

6

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9 September 2017

publication date

2 April 2013

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Pigment Cell & Melanoma Research

9 September 2017

published in

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9 September 2017

volume

26

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9 September 2017

issue

3

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9 September 2017

page(s)

408-414

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The role of HER3, the unpretentious member of the HER family, in cancer biology and cancer therapeutics

9 September 2017

cites work

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Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway.

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HER3 comes of age: new insights into its functions and role in signaling, tumor biology, and cancer therapy

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ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines

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High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor

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Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt

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Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

21 January 2018

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The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

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Direct binding of the EGF-like domain of neuregulin-1 to integrins ({alpha}v{beta}3 and {alpha}6{beta}4) is involved in neuregulin-1/ErbB signaling

21 January 2018

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Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium

21 January 2018

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Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

21 January 2018

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Differential expression of NDF/neuregulin receptors ErbB-3 and ErbB-4 and involvement in inhibition of neuronal differentiation.

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Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

21 January 2018

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HER3 is a determinant for poor prognosis in melanoma

21 January 2018

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PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

21 January 2018

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Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry

21 January 2018

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All EGF(ErbB) receptors have preformed homo- and heterodimeric structures in living cells.

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Relation of cytogenetic abnormalities and clinical outcome in metastatic melanoma

21 January 2018

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Phosphoproteomic screen identifies potential therapeutic targets in melanoma

21 January 2018

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A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

21 January 2018

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Heregulin-induced activation of ErbB3 by EGFR tyrosine kinase activity promotes tumor growth and metastasis in melanoma cells

21 January 2018

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ErbB4 isoforms selectively regulate growth factor induced Madin-Darby canine kidney cell tubulogenesis

21 January 2018

1 reference

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Akt, FoxO and regulation of apoptosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12089

A Notch1-neuregulin1 autocrine signaling loop contributes to melanoma growth

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12089

Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

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https://api.crossref.org/works/10.1111%2FPCMR.12089

21 January 2018

Identifiers

DOI

10.1111/PCMR.12089

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9 September 2017

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