Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry (Q40484925)

20 September 2017

Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry (English)

1 reference

20 September 2017

0 references

Incheol Shin

1

1 reference

20 September 2017

Jeremy Rotty

series ordinal

2

1 reference

20 September 2017

Frederick Y Wu

series ordinal

3

1 reference

20 September 2017

Carlos L Arteaga

series ordinal

4

1 reference

20 September 2017

language of work or name

English

0 references

publication date

3 December 2004

1 reference

Journal of Biological Chemistry

20 September 2017

1 reference

20 September 2017

280

1 reference

20 September 2017

6055-6063

1 reference

20 September 2017

7

1 reference

CDK inhibitors: positive and negative regulators of G1-phase progression

20 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21Cip1 and p27Kip1 in anchorage-independent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Transport into and out of the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

From nucleoporins to nuclear pore complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Distinct functions for the two importin subunits in nuclear protein import

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Nucleocytoplasmic transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Role of translocation in the activation and function of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Threonine 308 phosphorylated form of Akt translocates to the nucleus of PC12 cells under nerve growth factor stimulation and associates with the nuclear matrix protein nucleolin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Akt activation by growth factors is a multiple-step process: the role of the PH domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Phosphorylation on protein kinase C sites inhibits nuclear import of lamin B2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Selective nuclear transport of the Drosophila morphogen dorsal can be established by a signaling pathway involving the transmembrane protein Toll and protein kinase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

A protein kinase-A recognition sequence is structurally linked to transformation by p59v-rel and cytoplasmic retention of p68c-rel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

The cell cycle-dependent nuclear import of v-Jun is regulated by phosphorylation of a serine adjacent to the nuclear localization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Phosphorylation of p27Kip1 at Threonine 198 by p90 Ribosomal Protein S6 Kinases Promotes Its Binding to 14-3-3 and Cytoplasmic Localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Cyclin E-mediated elimination of p27 requires its interaction with the nuclear pore-associated protein mNPAP60.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Characterization and targeted disruption of murine Nup50, a p27(Kip1)-interacting component of the nuclear pore complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412367200

21 January 2018

Identifiers

DOI

10.1074/JBC.M412367200

1 reference

20 September 2017

1 reference