PCAF acetylates Runx2 and promotes osteoblast differentiation (Q39184093)

9 September 2017

PCAF acetylates Runx2 and promotes osteoblast differentiation (English)

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9 September 2017

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Chao-Yang Wang

1

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9 September 2017

Shu-Feng Yang

2

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9 September 2017

Zhong Wang

3

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9 September 2017

Jun-Ming Tan

4

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9 September 2017

Shun-Min Xing

5

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9 September 2017

De-Chun Chen

6

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9 September 2017

Sheng-Ming Xu

7

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9 September 2017

Wen Yuan

8

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9 September 2017

7 March 2013

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Journal of Bone and Mineral Metabolism

9 September 2017

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9 September 2017

31

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4

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9 September 2017

381-389

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https://scigraph.springernature.com/pub.10.1007/s00774-013-0428-y

9 September 2017

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Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

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Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

21 January 2018

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Serine phosphorylation of RUNX2 with novel potential functions as negative regulatory mechanisms

21 January 2018

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GSK-3beta controls osteogenesis through regulating Runx2 activity

21 January 2018

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c-Jun N-terminal kinase 1 negatively regulates osteoblastic differentiation induced by BMP2 via phosphorylation of Runx2 at Ser104.

21 January 2018

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Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2.

21 January 2018

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Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation

21 January 2018

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Cyclin D1-cdk4 induce runx2 ubiquitination and degradation

21 January 2018

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p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

21 January 2018

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PCAF acetylates {beta}-catenin and improves its stability

21 January 2018

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Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation.

21 January 2018

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PCAF interacts with XBP-1S and mediates XBP-1S-dependent transcription

21 January 2018

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Biomechanical stimulation of osteoblast gene expression requires phosphorylation of the RUNX2 transcription factor

21 January 2018

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Histone acetyltransferases

21 January 2018

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Acerogenin A, a natural compound isolated from Acer nikoense Maxim, stimulates osteoblast differentiation through bone morphogenetic protein action

21 January 2018

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Harmine promotes osteoblast differentiation through bone morphogenetic protein signaling

21 January 2018

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A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2

21 January 2018

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Xanthohumol from the hop plant stimulates osteoblast differentiation by RUNX2 activation

21 January 2018

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Post-translational Regulation of Runx2 in Bone and Cartilage

21 January 2018

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Transcription-dependent degradation controls the stability of the SREBP family of transcription factors.

21 January 2018

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The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

21 January 2018

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FGF2-activated ERK mitogen-activated protein kinase enhances Runx2 acetylation and stabilization

21 January 2018

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BMP2-activated Erk/MAP kinase stabilizes Runx2 by increasing p300 levels and histone acetyltransferase activity

21 January 2018

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Bone morphogenetic protein-2 stimulates Runx2 acetylation

21 January 2018

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Histone deacetylase inhibitors promote osteoblast maturation

21 January 2018

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Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation

21 January 2018

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The journey of resveratrol from yeast to human

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21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23468178

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A Pro250Arg substitution in mouse Fgfr1 causes increased expression of Cbfa1 and premature fusion of calvarial sutures

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23468178

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

OP-1 (BMP-7) stimulates osteoprogenitor cell differentiation in the presence of polymethylmethacrylate particles

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23468178

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00774-013-0428-Y

1 reference

9 September 2017

1 reference