PCAF acetylates Runx2 and promotes osteoblast differentiation (Q39184093)

9 September 2017

title

PCAF acetylates Runx2 and promotes osteoblast differentiation (English)

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9 September 2017

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Chao-Yang Wang

1

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9 September 2017

Shu-Feng Yang

2

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9 September 2017

Zhong Wang

3

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9 September 2017

Jun-Ming Tan

4

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9 September 2017

Shun-Min Xing

5

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9 September 2017

De-Chun Chen

6

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9 September 2017

Sheng-Ming Xu

7

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9 September 2017

Wen Yuan

8

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9 September 2017

publication date

7 March 2013

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Journal of Bone and Mineral Metabolism

9 September 2017

published in

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9 September 2017

volume

31

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9 September 2017

issue

4

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9 September 2017

page(s)

381-389

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Therapeutic approaches to bone diseases

9 September 2017

cites work

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GSK-3beta controls osteogenesis through regulating Runx2 activity

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Cyclin D1-cdk4 induce runx2 ubiquitination and degradation

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p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

21 January 2018

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PCAF acetylates {beta}-catenin and improves its stability

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Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation.

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PCAF interacts with XBP-1S and mediates XBP-1S-dependent transcription

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Biomechanical stimulation of osteoblast gene expression requires phosphorylation of the RUNX2 transcription factor

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Histone acetyltransferases

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Acerogenin A, a natural compound isolated from Acer nikoense Maxim, stimulates osteoblast differentiation through bone morphogenetic protein action

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Harmine promotes osteoblast differentiation through bone morphogenetic protein signaling

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A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2

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Xanthohumol from the hop plant stimulates osteoblast differentiation by RUNX2 activation

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BMP2-activated Erk/MAP kinase stabilizes Runx2 by increasing p300 levels and histone acetyltransferase activity

21 January 2018

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Bone morphogenetic protein-2 stimulates Runx2 acetylation

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Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23468178

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12 December 2020

based on heuristic

A Pro250Arg substitution in mouse Fgfr1 causes increased expression of Cbfa1 and premature fusion of calvarial sutures

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23468178

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23468178

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00774-013-0428-Y

1 reference

9 September 2017

1 reference