Liver macrophages in tissue homeostasis and disease (Q39187324)

9 September 2017

title

Liver macrophages in tissue homeostasis and disease (English)

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9 September 2017

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Oliver Krenkel

1

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9 September 2017

Frank Tacke

series ordinal

2

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9 September 2017

publication date

20 March 2017

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Nature Reviews Immunology

9 September 2017

published in

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9 September 2017

volume

17

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9 September 2017

issue

5

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9 September 2017

page(s)

306-321

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Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species

9 September 2017

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Characterization of Kupffer cells in livers of developing mice

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Tissue-resident macrophages

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Macrophage heterogeneity in liver injury and fibrosis

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Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

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Macrophages: central regulators of iron balance

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Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression

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Differentiation and function of Kupffer cells

21 January 2018

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Liver Kupffer cells rapidly remove red blood cell-derived vesicles from the circulation by scavenger receptors

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2017.11

Identification of the haemoglobin scavenger receptor.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2017.11

Plasma cholesteryl ester transfer protein is predominantly derived from Kupffer cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2017.11

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2017.11

C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages

21 January 2018

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21 January 2018

Fetal HSCs versus EMP2s.

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21 January 2018

Homegrown Macrophages.

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Specification of tissue-resident macrophages during organogenesis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2017.11

Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2017.11

Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Liver inflammation abrogates immunological tolerance induced by Kupffer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Mechanism of T cell tolerance induction by murine hepatic Kupffer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Chemokine (C-C motif) receptor 2-positive monocytes aggravate the early phase of acetaminophen-induced acute liver injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Hematopoietic stem cells: concepts, definitions, and the new reality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Rapid and accurate large-scale coestimation of sequence alignments and phylogenetic trees

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Origin of monocytes and macrophages in a committed progenitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Roles for chemokines in liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Macrophages: development and tissue specialization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Monocytes give rise to mucosal, but not splenic, conventional dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Comparison of gene expression profiles between human and mouse monocyte subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

A clonogenic progenitor with prominent plasmacytoid dendritic cell developmental potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Cell biology of antigen processing in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Combination of Mass Cytometry and Imaging Analysis Reveals Origin, Location, and Functional Repopulation of Liver Myeloid Cells in Mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Deciphering the transcriptional network of the dendritic cell lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The complex myeloid network of the liver with diverse functional capacity at steady state and in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Infiltrating monocyte-derived macrophages and resident kupffer cells display different ontogeny and functions in acute liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Immunology in the liver--from homeostasis to disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Kupffer Cells Undergo Fundamental Changes during the Development of Experimental NASH and Are Critical in Initiating Liver Damage and Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Bone marrow-derived and resident liver macrophages display unique transcriptomic signatures but similar biological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

A Reservoir of Mature Cavity Macrophages that Can Rapidly Invade Visceral Organs to Affect Tissue Repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Histidine-rich glycoprotein promotes macrophage activation and inflammation in chronic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

TLR-dependent cross talk between human Kupffer cells and NK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Tissue biology perspective on macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Characterization of the Inflammasome in Human Kupffer Cells in Response to Synthetic Agonists and Pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The inflammasome in liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Sterile inflammation in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Extracellular ATP induces P2X7 receptor activation in mouse Kupffer cells, leading to release of IL-1β, HMGB1, and PGE2, decreased MHC class I expression and necrotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Activation of NLRP3 and AIM2 inflammasomes in Kupffer cells in hepatic ischemia/reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The adaptor ASC exacerbates lethal Listeria monocytogenes infection by mediating IL-18 production in an inflammasome-dependent and -independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Bacterial recognition pathways that lead to inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Complementing the inflammasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Ablation of interaction between IL-33 and ST2+ regulatory T cells increases immune cell-mediated hepatitis and activated NK cell liver infiltration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine-driven inflammation and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Lactate reduces liver and pancreatic injury in Toll-like receptor- and inflammasome-mediated inflammation via GPR81-mediated suppression of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The role of the liver in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Identification and treatment of the Staphylococcus aureus reservoir in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-mediated tissue repair during bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Integrin αXβ₂ is a leukocyte receptor for Candida albicans and is essential for protection against fungal infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Bacterial infections in cirrhosis: a position statement based on the EASL Special Conference 2013.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Acute-on-chronic liver failure: A new syndrome that will re-classify cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Systemic inflammation in decompensated cirrhosis: Characterization and role in acute-on-chronic liver failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Characterization of Inflammatory Response in Acute-on-Chronic Liver Failure and Relationship with Prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Patients with acute-on-chronic liver failure have increased numbers of regulatory immune cells expressing the receptor tyrosine kinase MERTK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Role of hepatic resident and infiltrating macrophages in liver repair after acute injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Liver ischemia and reperfusion injury: new insights into mechanisms of innate-adaptive immune-mediated tissue inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Inflammatory monocytes recruited to the liver within 24 hours after virus-induced inflammation resemble Kupffer cells but are functionally distinct

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The fractalkine receptor CX₃CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Macrophages specifically regulate the concentration of their own growth factor in the circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

CCL2-CCR2 signaling promotes hepatic ischemia/reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

VEGFR1-positive macrophages facilitate liver repair and sinusoidal reconstruction after hepatic ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Liver Fibrosis: From Pathogenesis to Novel Therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The economic and clinical burden of nonalcoholic fatty liver disease in the United States and Europe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Interleukin-1 and inflammasomes in alcoholic liver disease/acute alcoholic hepatitis and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Lipid-Induced Signaling Causes Release of Inflammatory Extracellular Vesicles From Hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Macrophage autophagy protects against liver fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Chronic alcohol ingestion modulates hepatic macrophage populations and functions in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

CXC chemokine receptor 3 promotes steatohepatitis in mice through mediating inflammatory cytokines, macrophages and autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Pathophysiological mechanisms and therapeutic potentials of macrophages in non-alcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The macrophage activation marker sCD163 is associated with morphological disease stages in patients with non-alcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The macrophage activation marker sCD163 is associated with changes in NAFLD and metabolic profile during lifestyle intervention in obese children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Arginase 2 deficiency results in spontaneous steatohepatitis: a novel link between innate immune activation and hepatic de novo lipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Dietary fatty acid composition is sensed by the NLRP3 inflammasome: omega-3 fatty acid (DHA) prevents NLRP3 activation in human macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Fatty acid oxidation in macrophage polarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The global burden of viral hepatitis: better estimates to guide hepatitis elimination efforts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The role of Kupffer cells in hepatitis B and hepatitis C virus infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Hepatitis C virus induces interleukin-1β (IL-1β)/IL-18 in circulatory and resident liver macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Toll-like receptor-stimulated non-parenchymal liver cells can regulate hepatitis C virus replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

IL-34 and macrophage colony-stimulating factor are overexpressed in hepatitis C virus fibrosis and induce profibrotic macrophages that promote collagen synthesis by hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Hepatitis B virus particles preferably induce Kupffer cells to produce TGF-β1 over pro-inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Kupffer cell-derived IL-10 plays a key role in maintaining humoral immune tolerance in hepatitis B virus-persistent mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Kupffer Cells Support Hepatitis B Virus-Mediated CD8+ T Cell Exhaustion via Hepatitis B Core Antigen-TLR2 Interactions in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

NKp46(+) natural killer cells attenuate metabolism-induced hepatic fibrosis by regulating macrophage activation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

TLR4 enhances TGF-beta signaling and hepatic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Gut microbial translocation corrupts myeloid cell function to control bacterial infection during liver cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Liver fibrosis and repair: immune regulation of wound healing in a solid organ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Mechanisms of liver fibrosis resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

REpeated AutoLogous Infusions of STem cells In Cirrhosis (REALISTIC): a multicentre, phase II, open-label, randomised controlled trial of repeated autologous infusions of granulocyte colony-stimulating factor (GCSF) mobilised CD133+ bone marrow stem

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Therapy of experimental NASH and fibrosis with galectin inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR Phase 2b study design

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The inflammatory microenvironment in hepatocellular carcinoma: a pivotal role for tumor-associated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

21 January 2018

Cancer statistics, 2016

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Role of lymphocytes in liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Hepatic myeloid-derived suppressor cells in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Myeloid cells in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Targeting of tumour-infiltrating macrophages via CCL2/CCR2 signalling as a therapeutic strategy against hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The proinflammatory myeloid cell receptor TREM-1 controls Kupffer cell activation and development of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Tumor-Associated Neutrophils Recruit Macrophages and T-Regulatory Cells to Promote Progression of Hepatocellular Carcinoma and Resistance to Sorafenib

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

High tumor-infiltrating macrophage density predicts poor prognosis in patients with primary hepatocellular carcinoma after resection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Tumor-infiltrating monocytes/macrophages promote tumor invasion and migration by upregulating S100A8 and S100A9 expression in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Kupffer cell-monocyte communication is essential for initiating murine liver progenitor cell-mediated liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Tumor macrophages are pivotal constructors of tumor collagenous matrix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The yin and yang of evasion and immune activation in HCC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Opposite roles of cannabinoid receptors 1 and 2 in hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Macrophage activation and polarization: nomenclature and experimental guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Secretory leukocyte protease inhibitor: A pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Reduced monocyte HLA-DR expression: a novel biomarker of disease severity and outcome in acetaminophen-induced acute liver failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Long term intravital multiphoton microscopy imaging of immune cells in healthy and diseased liver using CXCR6.Gfp reporter mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

The soluble mannose receptor is released from the liver in cirrhotic patients, but is not associated with bacterial translocation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Decreased expression of the glucocorticoid receptor-GILZ pathway in Kupffer cells promotes liver inflammation in obese mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Pharmacological inhibition of the chemokine C-C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly-6C(+) macrophage infiltration in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.11

Therapeutic targeting of liver inflammation and fibrosis by nanomedicine

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28317925

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

In vivo analysis of dendritic cell development and homeostasis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28317925

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRI.2017.11

1 reference

9 September 2017

1 reference