The Formyl Peptide Receptors: Diversity of Ligands and Mechanism for Recognition (Q39196591)

9 September 2017

2 references

31 July 2019

15 December 2019

The Formyl Peptide Receptors: Diversity of Ligands and Mechanism for Recognition (English)

1 reference

9 September 2017

cell surface receptor

1 reference

31 July 2019

1 reference

15 December 2019

Hui-Qiong He

1

1 reference

PubMed ID

28335409

9 September 2017

Richard D Ye

series ordinal

2

1 reference

PubMed ID

28335409

9 September 2017

language of work or name

English

0 references

publication date

13 March 2017

3 references

9 September 2017

31 July 2019

15 December 2019

3 references

9 September 2017

31 July 2019

15 December 2019

22

1 reference

9 September 2017

3

1 reference

Creative Commons Attribution

9 September 2017

2 references

31 July 2019

15 December 2019

0 references

Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

N-formylmethionyl peptides as chemoattractants for leucocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Basic characteristics of the neutrophil receptors that recognize formylated peptides, a danger-associated molecular pattern generated by bacteria and mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

New development in studies of formyl-peptide receptors: critical roles in host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Synthesis and use of a novel N-formyl peptide derivative to isolate a human N-formyl peptide receptor cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The human N-formylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Cloning of a cDNA encoding a receptor related to the formyl peptide receptor of human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Adaptive evolution of formyl peptide receptors in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Role of formyl peptide receptor-like 1 (FPRL1/FPR2) in mononuclear phagocyte responses in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Leukocyte chemoattractant receptor FPR2 may accelerate atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Formyl peptide receptors at the interface of inflammation, angiogenesis and tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Formylpeptide receptors are critical for rapid neutrophil mobilization in host defense against Listeria monocytogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Reduced fear memory and anxiety-like behavior in mice lacking formylpeptide receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification of formyl peptides from Listeria monocytogenes and Staphylococcus aureus as potent chemoattractants for mouse neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Functional characterization of three mouse formyl peptide receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Serum amyloid A is a chemotactic agonist at FPR2, a low-affinity N-formylpeptide receptor on mouse neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Amyloid-beta induces chemotaxis and oxidant stress by acting at formylpeptide receptor 2, a G protein-coupled receptor expressed in phagocytes and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

F2L, a peptide derived from heme-binding protein, chemoattracts mouse neutrophils by specifically activating Fpr2, the low-affinity N-formylpeptide receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification and characterization of an endogenous chemotactic ligand specific for FPRL2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Characterization of Fpr-rs8, an atypical member of the mouse formyl peptide receptor gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Formyl peptide receptor-like proteins are a novel family of vomeronasal chemosensors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Characterization of two new members of the formyl peptide receptor gene family from 129S6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Intravascular danger signals guide neutrophils to sites of sterile inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Circulating mitochondrial DAMPs cause inflammatory responses to injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Intravital Imaging of Neutrophil Recruitment Reveals the Efficacy of FPR1 Blockade in Hepatic Ischemia-Reperfusion Injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Further studies on the structural requirements for synthetic peptide chemoattractants

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Chemotactic peptides. Mechanisms, functions, and possible role in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Defective polymorphonuclear leukocyte formyl peptide receptor(s) in juvenile periodontitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Formyl-methionyl-leucyl-phenylalanine causes bronchoconstriction in rabbits.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Haematological effects of inhalation of N-formyl-methionyl-leucyl-phenylalanine in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Structural changes of the ligand and of the receptor alters the receptor preference for neutrophil activating peptides starting with a formylmethionyl group

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Human mitochondria-derived N-formylated peptides are novel agonists equally active on FPR and FPRL1, while Listeria monocytogenes-derived peptides preferentially activate FPR

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Mitocryptide-2, a neutrophil-activating cryptide, is a specific endogenous agonist for formyl-peptide receptor-like 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

A proinflammatory peptide from Helicobacter pylori activates monocytes to induce lymphocyte dysfunction and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Cross-talk between fMLP and vitronectin receptors triggered by urokinase receptor-derived SRSRY peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Urokinase induces basophil chemotaxis through a urokinase receptor epitope that is an endogenous ligand for formyl peptide receptor-like 1 and -like 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The neurotoxic prion peptide fragment PrP(106-126) is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

VIP differentially activates beta2 integrins, CR1, and matrix metalloproteinase-9 in human monocytes through cAMP/PKA, EPAC, and PI-3K signaling pathways via VIP receptor type 1 and FPRL1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Activation of human monocytes by a formyl peptide receptor 2-derived pepducin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

A novel nonpeptide ligand for formyl peptide receptor-like 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification of novel small-molecule agonists for human formyl peptide receptors and pharmacophore models of their recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Formyl peptide receptor 1 and 2 dual agonist inhibits human neutrophil chemotaxis by the induction of chemoattractant receptor cross-desensitization.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Synthesis, enantioresolution, and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

3-(1H-indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide enantiomers with human formyl-peptide receptor agonist activity: molecular modeling of chiral recognition by FPR2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as selective agonists of human formyl-peptide receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

N-terminal residues of the chemotaxis inhibitory protein of Staphylococcus aureus are essential for blocking formylated peptide receptor but not C5a receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Uteroglobin suppresses allergen-induced TH2 differentiation by down-regulating the expression of serum amyloid A and SOCS-3 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Cyclization of the urokinase receptor-derived ser-arg-ser-arg-tyr Peptide generates a potent inhibitor of trans-endothelial migration of monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification of peptides that antagonize formyl peptide receptor-like 1-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Structural characterization and inhibitory profile of formyl peptide receptor 2 selective peptides descending from a PIP2-binding domain of gelsolin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The proteolytically stable peptidomimetic Pam-(Lys-βNSpe)6-NH2 selectively inhibits human neutrophil activation via formyl peptide receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The peptidomimetic Lau-(Lys-βNSpe)6-NH2 antagonizes formyl peptide receptor 2 expressed in mouse neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Pharmacological characterization of a novel nonpeptide antagonist for formyl peptide receptor-like 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Community-associated MRSA: what makes them special?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Human formyl peptide receptor 2 senses highly pathogenic Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Formyl peptide receptor-mediated proinflammatory consequences of peptide deformylase inhibition in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Receptor-dependent and -independent immunomodulatory effects of phenol-soluble modulin peptides from Staphylococcus aureus on human neutrophils are abrogated through peptide inactivation by reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

N36, a synthetic N-terminal heptad repeat domain of the HIV-1 envelope protein gp41, is an activator of human phagocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Activation of the chemotactic peptide receptor FPRL1 in monocytes phosphorylates the chemokine receptor CCR5 and attenuates cell responses to selected chemokines

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The HIV-1 cell entry inhibitor T-20 potently chemoattracts neutrophils by specifically activating the N-formylpeptide receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Basophils infiltrate human gastric mucosa at sites of Helicobacter pylori infection, and exhibit chemotaxis in response to H. pylori-derived peptide Hp(2-20)

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Promotion of formyl peptide receptor 1-mediated neutrophil chemotactic migration by antimicrobial peptides isolated from the centipede Scolopendra subspinipes mutilans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Local expression of the serum amyloid A and formyl peptide receptor-like 1 genes in synovial tissue is associated with matrix metalloproteinase production in patients with inflammatory arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Differential production of leukotriene B4 or prostaglandin E2 by WKYMVm or serum amyloid A via formyl peptide receptor-like 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Serum amyloid A opposes lipoxin A₄ to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Endogenous Acute Phase Serum Amyloid A Lacks Pro-Inflammatory Activity, Contrasting the Two Recombinant Variants That Activate Human Neutrophils through Different Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Serum amyloid A1 isoforms display different efficacy at Toll-like receptor 2 and formyl peptide receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Pleiotropic roles of formyl peptide receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Beta amyloid peptide (Abeta42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

N-Formylated humanin activates both formyl peptide receptor-like 1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Neutrophil NADPH-oxidase activation by an annexin AI peptide is transduced by the formyl peptide receptor (FPR), whereas an inhibitory signal is generated independently of the FPR family receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

FPRL1-mediated induction of superoxide in LL-37-stimulated IMR90 human fibroblast

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

LL-37 inhibits serum amyloid A-induced IL-8 production in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

An angiogenic role for the human peptide antibiotic LL-37/hCAP-18.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Leucine leucine-37 uses formyl peptide receptor-like 1 to activate signal transduction pathways, stimulate oncogenic gene expression, and enhance the invasiveness of ovarian cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification of FAM3D as a new endogenous chemotaxis agonist for the formyl peptide receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Distinct signaling cascades elicited by different formyl peptide receptor 2 (FPR2) agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met inhibits human monocyte-derived dendritic cell maturation via formyl peptide receptor and formyl peptide receptor-like 2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

A novel peptide agonist of formyl-peptide receptor-like 1 (ALX) displays anti-inflammatory and cardioprotective effects

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Tethered ligand library for discovery of peptide agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Design, synthesis and characterization of fMLF-mimicking AApeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Characterization of Quin-C1 for its anti-inflammatory property in a mouse model of bleomycin-induced lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Stable formyl peptide receptor agonists that activate the neutrophil NADPH-oxidase identified through screening of a compound library

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Molecular docking of 2-(benzimidazol-2-ylthio)-N-phenylacetamide-derived small-molecule agonists of human formyl peptide receptor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

High-throughput screening for small-molecule activators of neutrophils: identification of novel N-formyl peptide receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Resolution of inflammation: state of the art, definitions and terms

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification, cloning, and functional characterization of a murine lipoxin A4 receptor homologue gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Lipoxin A(4) metabolites/analogues from two commercial sources have no effects on TNF-alpha-mediated priming or activation through the neutrophil formyl peptide receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

What formyl peptide receptors, if any, are triggered by compound 43 and lipoxin A4?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Heterologously expressed formyl peptide receptor 2 (FPR2/ALX) does not respond to lipoxin A₄.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Lipoxin A4: a new class of ligand for the Ah receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Lipoxin A4 is a novel estrogen receptor modulator.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Resolvin D1 prevents TNF-α-mediated disruption of salivary epithelial formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Aspirin-triggered resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Resolvin D1 and resolvin D2 govern local inflammatory tone in obese fat

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Oxidized low-density lipoprotein-induced foam cell formation is mediated by formyl peptide receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Insider access: pepducin symposium explores a new approach to GPCR modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Turning receptors on and off with intracellular pepducins: new insights into G-protein-coupled receptor drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

A pepducin derived from the third intracellular loop of FPR2 is a partial agonist for direct activation of this receptor in neutrophils but a full agonist for cross-talk triggered reactivation of FPR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

A pepducin designed to modulate P2Y2R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Data on human neutrophil activation induced by pepducins with amino acid sequences derived from β2AR and CXCR4

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Selective inhibition of N-formylpeptide-induced neutrophil activation by carbamate-modified peptide analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Antibiotics and peptides with agonist and antagonist chemotactic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Development of potent antagonists for formyl peptide receptor 1 based on Boc-Phe-D-Leu-Phe-D-Leu-Phe-OH.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Chemotaxis inhibitory protein of Staphylococcus aureus binds specifically to the C5a and formylated peptide receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Characterisation of receptor binding by the chemotaxis inhibitory protein of Staphylococcus aureus and the effects of the host immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

A new staphylococcal anti-inflammatory protein that antagonizes the formyl peptide receptor-like 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Peptides derived from HIV-1, HIV-2, Ebola virus, SARS coronavirus and coronavirus 229E exhibit high affinity binding to the formyl peptide receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Cyclosporins: structure-activity relationships for the inhibition of the human FPR1 formylpeptide receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The immunosuppressant cyclosporin A antagonizes human formyl peptide receptor through inhibition of cognate ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Genetic ablation of the fpr1 gene confers protection from smoking-induced lung emphysema in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Mycobacteria attenuate nociceptive responses by formyl peptide receptor triggered opioid peptide release from neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Inhibition of phagocyte chemotaxis by uteroglobin, an inhibitor of blastocyst rejection.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Uteroglobin, a possible ligand of the lipoxin receptor inhibits serum amyloid A-driven inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Bioactive secondary metabolites of a marine Bacillus sp. inhibit superoxide generation and elastase release in human neutrophils by blocking formyl peptide receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The endogenous opioid spinorphin blocks fMet-Leu-Phe-induced neutrophil chemotaxis by acting as a specific antagonist at the N-formylpeptide receptor subtype FPR.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Two trypanocidal dipeptides from the roots of Zapoteca portoricensis (Fabaceae).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Inhibitory effects of spinorphin, a novel endogenous regulator, on chemotaxis, O2- generation, and exocytosis by N-formylmethionyl-leucyl-phenylalanine (FMLP)-stimulated neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Design and synthesis of new N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides as anti-inflammatory agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Design and synthesis of tryptophan containing dipeptide derivatives as formyl peptide receptor 1 antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Trp-Arg-Trp-Trp-Trp-Trp antagonizes formyl peptide receptor like 2-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Receptor-directed inhibition of chemotactic factor-induced neutrophil hyperactivity by pyrazolon derivatives. Definition of a chemotactic peptide antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Inhibition of human platelet cyclo-oxygenase activity by sulfinpyrazone and three of its metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

High-throughput screening with HyperCyt flow cytometry to detect small molecule formylpeptide receptor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The hederagenin saponin SMG-1 is a natural FMLP receptor inhibitor that suppresses human neutrophil activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

(2R,3R)-2-(3',4'-dihydroxybenzyl)-3-(3'',4''-dimethoxybenzyl)butyrolactone suppresses fMLP-induced superoxide production by inhibiting fMLP-receptor binding in human neutrophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

High-content screening: flow cytometry analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Biomolecular screening of formylpeptide receptor ligands with a sensitive, quantitative, high-throughput flow cytometry platform

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

A novel fluorescent cross-reactive formylpeptide receptor/formylpeptide receptor-like 1 hexapeptide ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification of functional domains in the formyl peptide receptor-like 1 for agonist-induced cell chemotaxis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification of an N-formyl peptide receptor ligand binding domain by a gain-of-function approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Human formyl peptide receptor function role of conserved and nonconserved charged residues

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification of a ligand binding site in the human neutrophil formyl peptide receptor using a site-specific fluorescent photoaffinity label and mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Linking agonist binding to histamine H1 receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Insight into structure-function relationship in phenol-soluble modulins using an alanine screen of the phenol-soluble modulin (PSM) α3 peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Peptide length and folding state govern the capacity of staphylococcal β-type phenol-soluble modulins to activate human formyl-peptide receptors 1 or 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The annexin I sequence gln(9)-ala(10)-trp(11)-phe(12) is a core structure for interaction with the formyl peptide receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct domains and downstream associated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Crystal structure of rhodopsin: A G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Non-peptide ligand binding to the formyl peptide receptor FPR2--A comparison to peptide ligand binding modes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

C- and N-terminal residue effect on peptide derivatives' antagonism toward the formyl-peptide receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Identification of novel formyl peptide receptor-like 1 agonists that induce macrophage tumor necrosis factor alpha production.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

The role of water in activation mechanism of human N-formyl peptide receptor 1 (FPR1) based on molecular dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Stimulation of human formyl peptide receptors by calpain inhibitors: homology modeling of receptors and ligand docking simulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES22030455

Chemotactic peptide-induced acute colitis in rabbits

21 January 2018

1 reference

12 December 2020

Leukotriene B4/antimicrobial peptide LL-37 proinflammatory circuits are mediated by BLT1 and FPR2/ALX and are counterregulated by lipoxin A4 and resolvin E1

1 reference

12 December 2020

Species and subtype variants of the N-formyl peptide chemotactic receptor reveal multiple important functional domains

1 reference

12 December 2020

The isolation and partial characterization of neutrophil chemotactic factors from Escherichia coli

1 reference

12 December 2020

Endotoxin augments hemodynamic and metabolic effects of formyl-methionyl-leucyl-phenylalanine (FMLP) in rabbits

1 reference

12 December 2020

Increased neutrophil receptors for and response to the proinflammatory bacterial peptide formyl-methionyl-leucyl-phenylalanine in Crohn's disease.

1 reference

12 December 2020

Opposing regulation of interleukin-8 and NF-kappaB responses by lipoxin A4 and serum amyloid A via the common lipoxin A receptor

1 reference

12 December 2020

Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L- leucyl-L-phenylalanine and cyclosporins A, B, C, D, and E

1 reference

12 December 2020

The interaction of 3,5-pyrazolidinedione drugs with receptors for f-Met-Leu-Phe on human neutrophil leukocytes: a study of the structure–activity relationship

1 reference

12 December 2020

N-formylpeptides induce two distinct concentration optima for mouse neutrophil chemotaxis by differential interaction with two N-formylpeptide receptor (FPR) subtypes. Molecular characterization of FPR2, a second mouse neutrophil FPR

1 reference

12 December 2020

Localization of radiolabeled chemotactic peptide at focal sites of Escherichia coli infection in rabbits: evidence for a receptor-specific mechanism.

1 reference

12 December 2020

T21/DP107, A synthetic leucine zipper-like domain of the HIV-1 envelope gp41, attracts and activates human phagocytes by using G-protein-coupled formyl peptide receptors

1 reference

12 December 2020

A synthetic peptide derived from human immunodeficiency virus type 1 gp120 downregulates the expression and function of chemokine receptors CCR5 and CXCR4 in monocytes by activating the 7-transmembrane G-protein-coupled receptor FPRL1/LXA4R.

1 reference

12 December 2020

Purification and identification of formyl-methionyl-leucyl-phenylalanine as the major peptide neutrophil chemotactic factor produced by Escherichia coli

1 reference

12 December 2020

Acute colitis produced by chemotactic peptides in rats and mice

1 reference

12 December 2020

Constituents and bioactive principles of Polygonum chinensis

1 reference

12 December 2020

Potential role of the formyl peptide receptor-like 1 (FPRL1) in inflammatory aspects of Alzheimer's disease.

1 reference

12 December 2020

Utilization of two seven-transmembrane, G protein-coupled receptors, formyl peptide receptor-like 1 and formyl peptide receptor, by the synthetic hexapeptide WKYMVm for human phagocyte activation

1 reference

12 December 2020

Pharmacophore model for bile acids recognition by the FPR receptor

1 reference

12 December 2020

Characterization of the Binding Site on the Formyl Peptide Receptor Using Three Receptor Mutants and Analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu

1 reference

12 December 2020

Hemodynamic and metabolic effects of intravenous formyl-methionyl-leucyl-phenylalanine (FMLP) in rabbits.

1 reference

12 December 2020

Proinflammatory proteases liberate a discrete high-affinity functional FPRL1 (CCR12) ligand from CCL23

1 reference

12 December 2020

Multiple domains of the N-formyl peptide receptor are required for high-affinity ligand binding. Construction and analysis of chimeric N-formyl peptide receptors.

1 reference

12 December 2020

The expression of β-defensin-2, 3 and LL-37 induced by Candida albicans phospholipomannan in human keratinocytes

1 reference

12 December 2020

A peptide with unique receptor specificity: stimulation of phosphoinositide hydrolysis and induction of superoxide generation in human neutrophils

1 reference

12 December 2020

Lipoxins: update and impact of endogenous pro-resolution lipid mediators

1 reference

12 December 2020

A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family

1 reference

12 December 2020

T20/DP178, an ectodomain peptide of human immunodeficiency virus type 1 gp41, is an activator of human phagocyte N-formyl peptide receptor.

1 reference

12 December 2020

An immunosuppressive retrovirus-derived hexapeptide interferes with intracellular signaling in monocytes and granulocytes through N-formylpeptide receptors

1 reference

12 December 2020

A neutrophil inhibitory pepducin derived from FPR1 expected to target FPR1 signaling hijacks the closely related FPR2 instead

1 reference

12 December 2020

The ligand binding site of the formyl peptide receptor maps in the transmembrane region

1 reference

12 December 2020

Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1

1 reference

12 December 2020

Synthetic peptide MMK-1 is a highly specific chemotactic agonist for leukocyte FPRL1.

1 reference

12 December 2020

10.3390/MOLECULES22030455

Identifiers

DOI

1 reference

release_vtp3kjqvcvfjzjv4frt66xeyme

9 September 2017

0 references

0 references

1 reference

PubMed ID

28335409