TDP-43 associates with stalled ribosomes and contributes to cell survival during cellular stress (Q39196751)

9 September 2017

title

TDP-43 associates with stalled ribosomes and contributes to cell survival during cellular stress (English)

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9 September 2017

Tomohiro Kabuta

2

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author name string

Shinji Higashi

1

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9 September 2017

Yoshitaka Nagai

3

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9 September 2017

Yukihiro Tsuchiya

4

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9 September 2017

Haruhiko Akiyama

5

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9 September 2017

Keiji Wada

6

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9 September 2017

language of work or name

English

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publication date

1 March 2013

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Journal of Neurochemistry

9 September 2017

published in

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9 September 2017

volume

126

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9 September 2017

issue

2

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9 September 2017

page(s)

288-300

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RNA granules: post-transcriptional and epigenetic modulators of gene expression

9 September 2017

cites work

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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

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Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

21 January 2018

1 reference

Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS.

21 January 2018

1 reference

Unraveling the mechanisms involved in motor neuron degeneration in ALS

21 January 2018

1 reference

Eukaryotic stress granules: the ins and outs of translation

21 January 2018

1 reference

Phosphorylation influences the translation state of FMRP-associated polyribosomes

21 January 2018

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From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

21 January 2018

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Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking

21 January 2018

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TDP-43 is recruited to stress granules in conditions of oxidative insult.

21 January 2018

1 reference

TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor

21 January 2018

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FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association

21 January 2018

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Efficacy of RNase inhibitors during brain polysome isolation

21 January 2018

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Stress granule assembly is mediated by prion-like aggregation of TIA-1

21 January 2018

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The peculiar interaction between mammalian prion protein and RNA

21 January 2018

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GIGYF2 is present in endosomal compartments in the mammalian brains and enhances IGF-1-induced ERK1/2 activation

21 January 2018

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Translational control in stress and apoptosis

21 January 2018

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Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies

21 January 2018

1 reference

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

21 January 2018

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Global mRNA stabilization preferentially linked to translational repression during the endoplasmic reticulum stress response

21 January 2018

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Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules

21 January 2018

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Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules

21 January 2018

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Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

21 January 2018

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Sequestration of TRAF2 into stress granules interrupts tumor necrosis factor signaling under stress conditions

21 January 2018

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Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

21 January 2018

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Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue

21 January 2018

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Amyotrophic lateral sclerosis-linked mutant SOD1 sequesters Hu antigen R (HuR) and TIA-1-related protein (TIAR): implications for impaired post-transcriptional regulation of vascular endothelial growth factor

21 January 2018

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TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1.

21 January 2018

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C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress

21 January 2018

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The translation machinery and 70 kd heat shock protein cooperate in protein synthesis

21 January 2018

1 reference

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

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D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells

21 January 2018

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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

21 January 2018

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MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay

21 January 2018

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Implications of the prion-related Q/N domains in TDP-43 and FUS.

21 January 2018

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Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

21 January 2018

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Does a loss of TDP-43 function cause neurodegeneration?

21 January 2018

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Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JNC.12194

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9 September 2017

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