Multi-cistronic vector encoding optimized safety switch for adoptive therapy with T-cell receptor-modified T cells (Q39201936)

9 September 2017

title

Multi-cistronic vector encoding optimized safety switch for adoptive therapy with T-cell receptor-modified T cells (English)

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9 September 2017

M M van Loenen

1

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9 September 2017

R de Boer

2

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9 September 2017

R S Hagedoorn

3

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9 September 2017

V Jankipersadsing

4

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9 September 2017

A L Amir

5

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9 September 2017

J H F Falkenburg

6

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9 September 2017

M H M Heemskerk

7

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9 September 2017

publication date

31 January 2013

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9 September 2017

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9 September 2017

volume

20

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9 September 2017

issue

8

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9 September 2017

page(s)

861-867

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Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes

9 September 2017

cites work

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Transfer of specificity by murine alpha and beta T-cell receptor genes

21 January 2018

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Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer

21 January 2018

1 reference

Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells

21 January 2018

1 reference

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

21 January 2018

1 reference

Cancer regression in patients after transfer of genetically engineered lymphocytes

21 January 2018

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Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1

21 January 2018

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Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

21 January 2018

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T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.

21 January 2018

1 reference

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy

21 January 2018

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Mixed T cell receptor dimers harbor potentially harmful neoreactivity

21 January 2018

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Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor

21 January 2018

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Gene expression changes associated with progression and response in chronic myeloid leukemia

21 January 2018

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PRAME, a gene encoding an antigen recognized on a human melanoma by cytolytic T cells, is expressed in acute leukaemia cells

21 January 2018

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Preferentially expressed antigen of melanoma (PRAME) in the development of diagnostic and therapeutic methods for hematological malignancies

21 January 2018

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The testis in immune privilege

21 January 2018

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Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis.

21 January 2018

1 reference

HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

21 January 2018

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The suicide gene therapy challenge: how to improve a successful gene therapy approach

21 January 2018

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Analysis of transgene-specific immune responses that limit the in vivo persistence of adoptively transferred HSV-TK-modified donor T cells after allogeneic hematopoietic cell transplantation

21 January 2018

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The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies

21 January 2018

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Inducible apoptosis as a safety switch for adoptive cell therapy

21 January 2018

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Genetic modification of human T cells with CD20: a strategy to purify and lyse transduced cells with anti-CD20 antibodies

21 January 2018

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Characterization of CD20-transduced T lymphocytes as an alternative suicide gene therapy approach for the treatment of graft-versus-host disease.

21 January 2018

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Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application

21 January 2018

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Retroviral transfer of human CD20 as a suicide gene for adoptive T-cell therapy

21 January 2018

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Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

21 January 2018

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An improved bicistronic CD20/tCD34 vector for efficient purification and in vivo depletion of gene-modified T cells for adoptive immunotherapy

21 January 2018

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Peptide-MHC class I tetrameric complexes display exquisite ligand specificity.

21 January 2018

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Efficiency of T-cell receptor expression in dual-specific T cells is controlled by the intrinsic qualities of the TCR chains within the TCR-CD3 complex.

21 January 2018

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Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3.

21 January 2018

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Antitumor effects of HSV-TK engineered donor lymphocytes after allogeneic stem-cell transplantation

21 January 2018

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Redirection of antileukemic reactivity of peripheral T lymphocytes using gene transfer of minor histocompatibility antigen HA-2-specific T-cell receptor complexes expressing a conserved alpha joining region

21 January 2018

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7 January 2021

Immunotherapy through TCR gene transfer

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7 January 2021

Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience

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7 January 2021

PRAME-Specific Allo-HLA-Restricted T Cells with Potent Antitumor Reactivity Useful for Therapeutic T-Cell Receptor Gene Transfer

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7 January 2021

Identifiers

DOI

10.1038/GT.2013.4

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Dimensions Publication ID

9 September 2017

1003576803

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Fatcat ID

release_vonp25conbemddq3glfefp5llu

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