Cross-talk between TLR4-MyD88-NF-κB and SCAP-SREBP2 pathways mediates macrophage foam cell formation (Q39207512)

10 September 2017

Cross-talk between TLR4-MyD88-NF-κB and SCAP-SREBP2 pathways mediates macrophage foam cell formation (English)

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10 September 2017

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Lung-Chih Li

1

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10 September 2017

Zac Varghese

2

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10 September 2017

John F Moorhead

3

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10 September 2017

Chien-Te Lee

4

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10 September 2017

Jin-Bor Chen

5

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10 September 2017

Xiong Z Ruan

6

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10 September 2017

18 January 2013

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American Journal of Physiology Heart and Circulatory Physiology

10 September 2017

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10 September 2017

304

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10 September 2017

H874-84

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10 September 2017

6

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Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

10 September 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Protein sensors for membrane sterols

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Inactivation of lysosomal proteases by oxidized low density lipoprotein is partially responsible for its poor degradation by mouse peritoneal macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Symptoms of chronic bronchitis, haemostatic factors, and coronary heart disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Macrophage foam cell formation with native low density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Immunopathogenesis of atherosclerosis: endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Inflammation in atherosclerosis

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Relation of Helicobacter pylori infection and coronary heart disease

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

MyD88 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation independent of signaling through Toll-like receptors 2 and 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Mechanisms of dysregulation of low-density lipoprotein receptor expression in vascular smooth muscle cells by inflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

21 January 2018

Quantitation of protein

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https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Lovastatin inhibits gene expression of type-I scavenger receptor in THP-1 human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Cholesterol or triglyceride loading of human monocyte-derived macrophages by incubation with modified lipoproteins does not induce tissue factor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Tumor necrosis factor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Inflammation as a cardiovascular risk factor

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Inflammatory stress exacerbates lipid-mediated renal injury in ApoE/CD36/SRA triple knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Inflammatory stress increases unmodified LDL uptake via LDL receptor: an alternative pathway for macrophage foam-cell formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Advanced glycation end products (AGEs) increase human mesangial foam cell formation by increasing Golgi SCAP glycosylation in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00096.2012

10.1152/AJPHEART.00096.2012

21 January 2018

Identifiers

DOI

1 reference

10 September 2017

1 reference