Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition (Q39210896)

10 September 2017

title

Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition (English)

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10 September 2017

L Guo

1

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10 September 2017

C Chen

2

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10 September 2017

M Shi

3

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10 September 2017

F Wang

4

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10 September 2017

X Chen

5

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10 September 2017

D Diao

6

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10 September 2017

M Hu

7

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10 September 2017

M Yu

8

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10 September 2017

L Qian

9

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10 September 2017

N Guo

10

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10 September 2017

language of work or name

English

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publication date

14 January 2013

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10 September 2017

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10 September 2017

volume

32

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10 September 2017

issue

45

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10 September 2017

page(s)

5272-5282

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https://api.crossref.org/works/10.1038%2FONC.2012.573

10 September 2017

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Cancer stem cells and EMT in carcinoma.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

TGFbeta and cancer metastasis: an inflammation link.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

TGF-beta and epithelial-to-mesenchymal transitions

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

p38 maintains E-cadherin expression by modulating TAK1-NF-kappa B during epithelial-to-mesenchymal transition.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

The oncostatin M signalling pathway: reversing the neoplastic phenotype?

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Oncostatin M induces the differentiation of breast cancer cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Oncostatin M induces cell detachment and enhances the metastatic capacity of T-47D human breast carcinoma cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Oncostatin M, a cytokine released by activated mononuclear cells, induces epithelial cell-myofibroblast transdifferentiation via Jak/Stat pathway activation

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Breast cancer cells stimulate neutrophils to produce oncostatin M: potential implications for tumor progression

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

The basics of epithelial-mesenchymal transition

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Tumor-associated macrophages: the double-edged sword in cancer progression.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling?

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

AP-1: a double-edged sword in tumorigenesis

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Oncostatin M: signal transduction and biological activity

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

The tumor suppressor microRNA let-7 represses the HMGA2 oncogene

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

miR-200 regulates PDGF-D-mediated epithelial-mesenchymal transition, adhesion, and invasion of prostate cancer cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Regulation of transcription factor Twist expression by the DNA architectural protein high mobility group A2 during epithelial-to-mesenchymal transition

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

EMT: when epithelial cells decide to become mesenchymal-like cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

A cytokine-mediated link between innate immunity, inflammation, and cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Overexpression of the oncostatin M receptor in cervical squamous cell carcinoma cells is associated with a pro-angiogenic phenotype and increased cell motility and invasiveness

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

Oncostatin M-induced effects on EMT in human proximal tubular cells: differential role of ERK signaling.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

Requirement for high mobility group protein HMGI-C interaction with STAT3 inhibitor PIAS3 in repression of alpha-subunit of epithelial Na+ channel (alpha-ENaC) transcription by Ras activation in salivary epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

The let-7 family of microRNAs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

Identification of let-7-regulated oncofetal genes

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.573

IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

let-7 regulates self renewal and tumorigenicity of breast cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

Induced pluripotent stem cell lines derived from human somatic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

The high mobility group protein HMGA2: a co-regulator of chromatin structure and pluripotency in stem cells?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

The β2-adrenergic receptor and Her2 comprise a positive feedback loop in human breast cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.573

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.573

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Dimensions Publication ID

10 September 2017

1030198930

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Fatcat ID

release_m7zsj34ltrhjbhtsxwi7cdchui

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1 reference