mRNA Cancer Vaccines-Messages that Prevail (Q39236800)

10 September 2017

mRNA Cancer Vaccines-Messages that Prevail (English)

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10 September 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28401358%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1

Christian Grunwitz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28401358%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

publication date

31 March 2017

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Current Topics in Microbiology and Immunology

10 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28401358%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

405

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28401358%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

145-164

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28401358%20AND%20SRC:MED&resulttype=core&format=json

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

5 June 2020

cites work

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https://api.crossref.org/works/10.1007%2F82_2017_509

Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

AU-rich elements and associated factors: are there unifying principles?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class I and class II molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Targeting antigen in mature dendritic cells for simultaneous stimulation of CD4+ and CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Aerosol and intravenous transfection of human alpha 1-antitrypsin gene to lungs of rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Inclusion of cholesterol in DOTAP transfection complexes increases the delivery of DNA to cells in vitro in the presence of serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

mTOR inhibition improves antitumor effects of vaccination with antigen-encoding RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

The impact of miRNA target sites in coding sequences and in 3'UTRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

5'-Triphosphate RNA is the ligand for RIG-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

TLR ignores methylated RNA?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

mRNA is an endogenous ligand for Toll-like receptor 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Modification of CEA with both CRT and TAT PTD induces potent anti-tumor immune responses in RNA-pulsed DC vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Self-adjuvanted mRNA vaccines induce local innate immune responses that lead to a potent and boostable adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: a first-in-man phase I/IIa study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Induction of virus-specific cytotoxic T lymphocytes in vivo by liposome-entrapped mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

A critical analysis of codon optimization in human therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Intestinal M cells: the fallible sentinels?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Towards Targeted Delivery Systems: Ligand Conjugation Strategies for mRNA Nanoparticle Tumor Vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Messenger RNA (mRNA) nanoparticle tumour vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Activation of MDA5 requires higher-order RNA structures generated during virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Intranasal M cell uptake of nanoparticles is independently influenced by targeting ligands and buffer ionic strength.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Long-term survival correlates with immunological responses in renal cell carcinoma patients treated with mRNA-based immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

mRNA-based therapeutics--developing a new class of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

+1 Frameshifting as a novel mechanism to generate a cryptic cytotoxic T lymphocyte epitope derived from human interleukin 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Toll-like receptor-dependent activation of several human blood cell types by protamine-condensed mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Constitutive display of cryptic translation products by MHC class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Uptake of synthetic naked RNA by skin-resident dendritic cells via macropinocytosis allows antigen expression and induction of T-cell responses in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

In vitro and in vivo mRNA delivery using lipid-enveloped pH-responsive polymer nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Genetic immunization is a simple method for eliciting an immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Intratumoral administration of mRNA encoding a fusokine consisting of IFN-β and the ectodomain of the TGF-β receptor II potentiates antitumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Intratumoral delivery of mRNA: Overcoming obstacles for effective immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Intratumoral Delivery of TriMix mRNA Results in T-cell Activation by Cross-Presenting Dendritic Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Results of the first phase I/II clinical vaccination trial with direct injection of mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Direct injection of protamine-protected mRNA: results of a phase 1/2 vaccination trial in metastatic melanoma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Function of RIG-I-like receptors in antiviral innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Mechanism of oligonucleotide release from cationic liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Simultaneous ex vivo quantification of antigen-specific CD4+ and CD8+ T cell responses using in vitro transcribed RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

Increased Antigen Presentation Efficiency by Coupling Antigens to MHC Class I Trafficking Signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F82_2017_509

21 January 2018

Identifiers

DOI

10.1007/82_2017_509

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28401358%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference