Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR. (Q39252731)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17617058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR (English)

1 reference

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1 January 2020

0 references

7

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1 January 2020

Grahame Hardie

9

1 reference

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1 January 2020

Carol MacKintosh

10

1 reference

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1 January 2020

author name string

Kathryn M Geraghty

1

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1 January 2020

Shuai Chen

2

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1 January 2020

Jean E Harthill

3

1 reference

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1 January 2020

Adel F Ibrahim

4

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1 January 2020

Rachel Toth

5

1 reference

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1 January 2020

Nick A Morrice

6

1 reference

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1 January 2020

Greg B Moorhead

8

1 reference

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1 January 2020

language of work or name

English

0 references

publication date

1 October 2007

1 reference

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1 January 2020

1 reference

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1 January 2020

volume

407

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1 January 2020

issue

2

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1 January 2020

page(s)

231-241

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Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane

1 January 2020

cites work

1 reference

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Resistance exercise and insulin regulate AS160 and interaction with 14-3-3 in human skeletal muscle.

10 September 2017

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Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1

10 September 2017

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TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition

10 September 2017

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10 September 2017

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Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

10 September 2017

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Bridging the GAP between insulin signaling and GLUT4 translocation

10 September 2017

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The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

10 September 2017

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Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking

10 September 2017

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AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain

10 September 2017

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Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects

10 September 2017

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Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer

10 September 2017

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Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization

10 September 2017

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The LKB1 tumor suppressor negatively regulates mTOR signaling

10 September 2017

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Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes.

10 September 2017

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Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins

10 September 2017

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14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)

10 September 2017

1 reference

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TSC2 mediates cellular energy response to control cell growth and survival

10 September 2017

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14-3-3s regulate fructose-2,6-bisphosphate levels by binding to PKB-phosphorylated cardiac fructose-2,6-bisphosphate kinase/phosphatase

10 September 2017

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Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation

10 September 2017

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The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif

10 September 2017

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Regulation of TSC2 by 14-3-3 binding

10 September 2017

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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

10 September 2017

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Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes

10 September 2017

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A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain

10 September 2017

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Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site

10 September 2017

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Role of AMP-activated protein kinase in mechanism of metformin action

10 September 2017

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A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta

10 September 2017

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Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth

10 September 2017

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Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

10 September 2017

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Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

10 September 2017

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Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells

10 September 2017

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BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

14 September 2017

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Interaction of the Akt substrate, AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase

14 September 2017

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Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome

14 September 2017

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Identification of a conserved motif required for mTOR signaling

25 September 2017

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Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes

25 September 2017

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A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160.

25 September 2017

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14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking

17 June 2018

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Regulation of the 14-3-3-binding protein p39 by growth factors and nutrients in rat PC12 pheochromocytoma cells

17 June 2018

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The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP-activated protein kinase signals regulating GLUT4 traffic.

17 June 2018

1 reference

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α2 isoform-specific activation of 5'adenosine monophosphate-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-β-D-ribonucleoside at a physiological level activates glucose transport and increases glucose transporter 4 in mouse skeletal mu

21 August 2018

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Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study

21 August 2018

1 reference

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Increased phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle in response to insulin or contractile activity

21 August 2018

1 reference

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AMPK-Mediated AS160 Phosphorylation in Skeletal Muscle Is Dependent on AMPK Catalytic and Regulatory Subunits

21 August 2018

1 reference

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Automated identification and quantification of protein phosphorylation sites by LC/MS on a hybrid triple quadrupole linear ion trap mass spectrometer

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17617058

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cellular mechanism of insulin resistance: potential links with inflammation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17617058

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17617058

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20070649

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17617058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17617058%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference