Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents (Q39256859)

10 September 2017

Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents (English)

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10 September 2017

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Maria Beatrice Morelli

Maria Beatrice Morelli

2

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Massimo Nabissi

Massimo Nabissi

1

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Giorgio Santoni

Giorgio Santoni

4

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Matteo Santoni

Matteo Santoni

3

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language of work or name

English

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publication date

18 October 2012

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10 September 2017

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10 September 2017

34

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10 September 2017

1

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10 September 2017

48-57

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Therapeutic options for recurrent high-grade glioma in adult patients: recent advances

10 September 2017

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Targeting malignant glioma survival signalling to improve clinical outcomes.

21 January 2018

1 reference

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Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma

21 January 2018

1 reference

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Capsaicin-induced apoptosis of glioma cells is mediated by TRPV1 vanilloid receptor and requires p38 MAPK activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

TRPV2 channel negatively controls glioma cell proliferation and resistance to Fas-induced apoptosis in ERK-dependent manner.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Permeation and selectivity of TRP channels

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Outer pore architecture of a Ca2+-selective TRP channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

TRPV channels in tumor growth and progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Capsaicin combined with local anesthetics preferentially prolongs sensory/nociceptive block in rat sciatic nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

TRP channels and cancer: new targets for diagnosis and chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Activity-dependent targeting of TRPV1 with a pore-permeating capsaicin analog

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

A capsaicin-receptor homologue with a high threshold for noxious heat

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

The transient receptor potential vanilloid-2 cation channel impairs glioblastoma stem-like cell proliferation and promotes differentiation

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

PI3-kinase promotes TRPV2 activity independently of channel translocation to the plasma membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Cannabinoids for cancer treatment: progress and promise

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Cannabinoids and gliomas.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Cannabidiol--recent advances

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

21 January 2018

1 reference

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Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival

21 January 2018

1 reference

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A combined preclinical therapy of cannabinoids and temozolomide against glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism.

21 January 2018

1 reference

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Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Diversity of DNA damage response of astrocytes and glioblastoma cell lines with various p53 status to treatment with etoposide and temozolomide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+ tumor-derived cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Temozolomide-mediated radiation enhancement in glioblastoma: a report on underlying mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

TRPV4 enhances the cellular uptake of aminoglycoside antibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Chemotherapy resistance of glioblastoma stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Doxorubicin induces the persistent activation of intracellular transglutaminase 2 that protects from cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

The pore of TRP channels: trivial or neglected?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

A pharmacodynamic analysis method to determine the relative importance of drug concentration and treatment time on effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

Identification of human brain tumour initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS328

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGS328

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10 September 2017

1 reference

PubMed ID

23079154