Radixin (Q3928887)

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mammalian protein found in Homo sapiens

ESP10
RDX
radixin

Language	Label	Description	Also known as
English	Radixin	mammalian protein found in Homo sapiens	ESP10 RDX radixin

Statements

1 reference

13 November 2019

UniProt protein ID

FERM/acyl-CoA-binding protein superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

Moesin tail domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

PH-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

FERM superfamily, second domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

Ezrin/radixin/moesin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

Ubiquitin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

Band 4.1 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM central domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM, C-terminal PH-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein domain specific binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

1 reference

8 April 2019

Ezrin and radixin both regulate the apical membrane localization of ABCC2 (MRP2) in human intestinal epithelial Caco-2 cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

protein kinase A binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

cytoskeletal protein binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

protein binding

determination method

6 references

8 April 2019

The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

Cytoskeletal protein radixin activates integrin alpha(M)beta(2) by binding to its cytoplasmic tail

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

Ezrin and radixin both regulate the apical membrane localization of ABCC2 (MRP2) in human intestinal epithelial Caco-2 cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

1 reference

26 September 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35241&geneProductId=UniProtKB:P35241

determination method

cadherin binding

determination method

1 reference

26 September 2017

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35241&geneProductId=UniProtKB:P35241

determination method

determination method

1 reference

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

cadherin binding

determination method

1 reference

8 April 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35241&geneProductId=UniProtKB:P35241

determination method

plasma membrane

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

apical part of cell

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

apical plasma membrane

determination method

1 reference

8 April 2019

Ezrin and radixin both regulate the apical membrane localization of ABCC2 (MRP2) in human intestinal epithelial Caco-2 cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

extracellular exosome

determination method

4 references

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35241&geneProductId=UniProtKB:P35241

determination method

26 September 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35241&geneProductId=UniProtKB:P35241

determination method

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35241&geneProductId=UniProtKB:P35241

determination method

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35241&geneProductId=UniProtKB:P35241

determination method

determination method

2 references

determination method

1 reference

8 April 2019

Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

extracellular space

determination method

1 reference

26 September 2017

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35241&geneProductId=UniProtKB:P35241

determination method

extracellular space

determination method

1 reference

8 April 2019

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

cell projection

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

extracellular exosome

determination method

4 references

8 April 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

biological process

regulation of cell size

determination method

1 reference

8 April 2019

Radixin regulates cell migration and cell-cell adhesion through Rac1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

establishment of endothelial barrier

determination method

1 reference

8 April 2019

MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

microvillus assembly

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

regulation of organelle assembly

determination method

1 reference

8 April 2019

The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

positive regulation of cell migration

determination method

1 reference

8 April 2019

Radixin regulates cell migration and cell-cell adhesion through Rac1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

regulation of GTPase activity

determination method

1 reference

8 April 2019

Radixin regulates cell migration and cell-cell adhesion through Rac1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

negative regulation of homotypic cell-cell adhesion

determination method

1 reference

8 April 2019

Radixin regulates cell migration and cell-cell adhesion through Rac1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

regulation of actin filament bundle assembly

determination method

1 reference

8 April 2019

Radixin regulates cell migration and cell-cell adhesion through Rac1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

positive regulation of gene expression

determination method

1 reference

8 April 2019

MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

negative regulation of GTPase activity

determination method

1 reference

8 April 2019

Radixin regulates cell migration and cell-cell adhesion through Rac1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

negative regulation of adherens junction organization

determination method

1 reference

8 April 2019

Radixin regulates cell migration and cell-cell adhesion through Rac1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

apical protein localization

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

actin filament capping

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

regulation of cell shape

determination method

1 reference

8 April 2019

Radixin regulates cell migration and cell-cell adhesion through Rac1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

protein kinase A signaling

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

regulation of ruffle assembly

determination method

1 reference

8 April 2019

Radixin regulates cell migration and cell-cell adhesion through Rac1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

positive regulation of protein localization to early endosome

determination method

1 reference

8 April 2019

The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

positive regulation of early endosome to late endosome transport

determination method

1 reference

8 April 2019

The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

negative regulation of cell size

determination method

1 reference

8 April 2019

Radixin regulates cell migration and cell-cell adhesion through Rac1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

regulation of Rap protein signal transduction

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

cellular response to platelet-derived growth factor stimulus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

barbed-end actin filament capping

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

protein localization to plasma membrane

determination method

1 reference

8 April 2019

Ezrin and radixin both regulate the apical membrane localization of ABCC2 (MRP2) in human intestinal epithelial Caco-2 cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35241

determination method

physically interacts with

determination method

Affinity Capture-MS

1 reference

https://thebiogrid.org/news/227

19 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

Gene Atlas image

PBB GE RDX 204969 s at fs.png
732 × 530; 12 KB

0 references

FERM, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

FERM, C-terminal PH-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

Band 4.1 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

FERM central domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

FERM conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35241

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000432112

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000432112

ENSP00000433580

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433580

ENSP00000436277

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000436277

ENSP00000437301

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000437301

ENSP00000445826

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000445826

ENSP00000431560

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000431560

ENSP00000432572

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000432572

ENSP00000432829

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000432829

ENSP00000434881

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000434881

ENSP00000435930

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435930

ENSP00000437140

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000437140

ENSP00000496121

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000496121

ENSP00000494060

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000494060

ENSP00000494706

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000494706

ENSP00000496503

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000496503

ENSP00000496414

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000496414

ENSP00000494693

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000494693

PDB structure ID

1 reference

10 November 2015

http://www.uniprot.org/uniprot/P26043.txt?version=139

1 reference

10 November 2015

http://www.uniprot.org/uniprot/P26043.txt?version=139

1 reference

10 November 2015

http://www.uniprot.org/uniprot/P26043.txt?version=139

1 reference

10 November 2015

http://www.uniprot.org/uniprot/P26043.txt?version=139

1 reference

10 November 2015

http://www.uniprot.org/uniprot/P26043.txt?version=139

1 reference

10 November 2015

http://www.uniprot.org/uniprot/P26043.txt?version=139

1 reference

10 November 2015

http://www.uniprot.org/uniprot/P26043.txt?version=139

1 reference

10 November 2015

http://www.uniprot.org/uniprot/P26043.txt?version=139

1 reference

10 November 2015

http://www.uniprot.org/uniprot/P26043.txt?version=139

1 reference

10 November 2015

http://www.uniprot.org/uniprot/P26043.txt?version=139

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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