Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma (Q39296277)

10 September 2017

Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma (English)

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10 September 2017

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Severine Navarro

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John W Upham

object named as

John W Upham

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Peter J. Hotez

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object named as

Peter J Hotez

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10 September 2017

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Thewarach Laha

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10 September 2017

Darren A Pickering

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10 September 2017

Ivana B Ferreira

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10 September 2017

Linda Jones

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10 September 2017

Stephanie Ryan

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Sally Troy

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Andrew Leech

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Bin Zhan

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Roger Prentice

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Tim Sparwasser

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John Croese

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10 September 2017

Christian R Engwerda

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Valerie Julia

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10 September 2017

Paul R Giacomin

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10 September 2017

Alex Loukas

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10 September 2017

language of work or name

English

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publication date

1 October 2016

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Science Translational Medicine

10 September 2017

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10 September 2017

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10 September 2017

362ra143

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10 September 2017

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Reduced risk of atopy among school-age children infected with geohelminth parasites in a rural area of the tropics

10 September 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Helminth therapy or elimination: epidemiological, immunological, and clinical considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Independent effects of intestinal parasite infection and domestic allergen exposure on risk of wheeze in Ethiopia: a nested case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Long-term treatment of intestinal helminths increases mite skin-test reactivity in Gabonese schoolchildren

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Effect of anthelmintic treatment on the allergic reactivity of children in a tropical slum

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Negative association of Enterobius infestation with asthma and rhinitis in primary school children in Taipei

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Atopy, intestinal helminth infection and total serum IgE in rural and urban adult Gambian communities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

IgE responses to Ascaris and mite tropomyosins are risk factors for asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

IL-22+ CD4+ T cells are associated with therapeutic trichuris trichiura infection in an ulcerative colitis patient.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

A proof of concept study establishing Necator americanus in Crohn's patients and reservoir donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Trichuris suis therapy for active ulcerative colitis: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Helminths and multiple sclerosis: will old friends give us new treatments for MS?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Experimental hookworm infection: a randomized placebo-controlled trial in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Helminth-host immunological interactions: prevention and control of immune-mediated diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Global asthma prevalence in adults: findings from the cross-sectional world health survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

An update on epidemiology of anaphylaxis in children and adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

EAACI position statement on asthma exacerbations and severe asthma

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

A review of prednisolone prescribing for children with acute asthma in the UK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Efficacy and safety of a novel nasal steroid, S0597, in patients with seasonal allergic rhinitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Patient-reported side effects, concerns and adherence to corticosteroid treatment for asthma, and comparison with physician estimates of side-effect prevalence: a UK-wide, cross-sectional study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Immunology of asthma and chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Asthma: mechanisms of disease persistence and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Suppression of type 2 immunity and allergic airway inflammation by secreted products of the helminth Heligmosomoides polygyrus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Therapeutic potential of larval excretory/secretory proteins of the pig whipworm Trichuris suis in allergic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Protection against allergic airway inflammation during the chronic and acute phases of Trichinella spiralis infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

A helminth immunomodulator reduces allergic and inflammatory responses by induction of IL-10-producing macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

AcCystatin, an immunoregulatory molecule from Angiostrongylus cantonensis, ameliorates the asthmatic response in an aluminium hydroxide/ovalbumin-induced rat model of asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Macrophage migration inhibitory factor homologs of anisakis simplex suppress Th2 response in allergic airway inflammation model via CD4+CD25+Foxp3+ T cell recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Hookworm excretory/secretory products induce interleukin-4 (IL-4)+ IL-10+ CD4+ T cell responses and suppress pathology in a mouse model of colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Hookworm products ameliorate dextran sodium sulfate-induced colitis in BALB/c mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

TIMPs of parasitic helminths - a large-scale analysis of high-throughput sequence datasets

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Diversity and dialogue in immunity to helminths.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

The hookworm tissue inhibitor of metalloproteases (Ac-TMP-1) modifies dendritic cell function and induces generation of CD4 and CD8 suppressor T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

It takes guts for tolerance: the phenomenon of oral tolerance and the regulation of autoimmune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Stromal cells confer lymph node-specific properties by shaping a unique microenvironment influencing local immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Bystander immunotherapy as a strategy to control allergen-driven airway inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Hay fever, hygiene, and household size

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Genome of the human hookworm Necator americanus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Suppression of allergic airway inflammation by helminth-induced regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Ancylostoma ceylanicum Excretory–Secretory Protein 2 Adopts a Netrin-Like Fold and Defines a Novel Family of Nematode Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

The intestinal micro-environment imprints stromal cells to promote efficient Treg induction in gut-draining lymph nodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Extrathymically generated regulatory T cells control mucosal TH2 inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Lung microbiota promotes tolerance to allergens in neonates via PD-L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

A helminth cathelicidin-like protein suppresses antigen processing and presentation in macrophages via inhibition of lysosomal vATPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Identification of the nuclear localization signals within the Epstein-Barr virus EBNA-6 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Isolation and subsequent analysis of murine lamina propria mononuclear cells from colonic tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

Old friends for breakfast

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8807

10.1126/SCITRANSLMED.AAF8807

21 January 2018

Identifiers

DOI

1 reference

release_hznvoq5ggfdydjnayl6s7ryub4

10 September 2017

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1 reference